Post-hospital-discharge COPD-patient monitoring using a dynamic baseline of symptoms/measurement
First Claim
1. A system configured to detect exacerbations based on dynamically-updated threshold values, the system comprising:
- one or more hardware processors configured by machine readable instructions to;
obtain a sequence of values for a metric that quantifies a lung-related characteristic of a subject, each value of the sequence corresponding to a time during a defined period different from a time to which at least another value of the sequence corresponds;
determine, based on a set of values of the sequence, a dynamic threshold for the subject;
adjust the dynamic threshold for the subject multiple times during the defined period based on other sets of values of the sequence, wherein each of the other sets of values includes at least one particular value that is not included in another set of values of the sequence, wherein a quantity of values in an individual set is inversely proportional to a duration of time that corresponds to the individual set;
compare one or more values of the metric to the multiple-adjusted dynamic threshold;
responsive to the comparison indicating exacerbation of a medical state of the subject, temporarily hold a current level of the multiple-adjusted dynamic threshold constant for a period of time; and
provide a notification to a caregiver based on a comparison of one or more additional values of the metric with the temporarily held current level of the multiple-adjusted dynamic threshold, wherein the notification indicates an ongoing exacerbation of the medical state of the subject.
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Accused Products
Abstract
Systems and methods for monitoring subjects after discharge from a hospital use a dynamic baseline to determine whether a caregiver needs to be notified regarding exacerbation of a medical state of a subject. The subjects are chronic obstructive pulmonary disease (COPD) patients. The dynamic baseline is determined by aggregating (for example averaging) multiple values of a sequence of values for a metric that quantifies one or both of a patient symptom (e.g. the number of overnight apnea occurrences) and/or lung function of a subject (e.g. forced expiratory volume in 1 second). Multiple metrics may be combined to generate the value that is monitored for a subject.
15 Citations
20 Claims
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1. A system configured to detect exacerbations based on dynamically-updated threshold values, the system comprising:
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one or more hardware processors configured by machine readable instructions to; obtain a sequence of values for a metric that quantifies a lung-related characteristic of a subject, each value of the sequence corresponding to a time during a defined period different from a time to which at least another value of the sequence corresponds; determine, based on a set of values of the sequence, a dynamic threshold for the subject; adjust the dynamic threshold for the subject multiple times during the defined period based on other sets of values of the sequence, wherein each of the other sets of values includes at least one particular value that is not included in another set of values of the sequence, wherein a quantity of values in an individual set is inversely proportional to a duration of time that corresponds to the individual set; compare one or more values of the metric to the multiple-adjusted dynamic threshold; responsive to the comparison indicating exacerbation of a medical state of the subject, temporarily hold a current level of the multiple-adjusted dynamic threshold constant for a period of time; and provide a notification to a caregiver based on a comparison of one or more additional values of the metric with the temporarily held current level of the multiple-adjusted dynamic threshold, wherein the notification indicates an ongoing exacerbation of the medical state of the subject. - View Dependent Claims (2, 3, 4, 5, 6, 7)
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8. A method for detecting exacerbations based on dynamically-updated threshold values with an exacerbation detection system, the system comprising one or more hardware processors configured by machine readable instructions, the method comprising:
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obtaining, with the one or more hardware processors, a sequence of values for a metric that quantifies a lung-related characteristic of a subject, each value of the sequence corresponding to a time during a defined period different from a time to which at least another value of the sequence corresponds; determining, with the one or more hardware processors, based on a set of values of the sequence, a dynamic threshold for the subject; adjusting, with the one or more hardware processors, the dynamic threshold for the subject multiple times during the defined period based on other sets of values of the sequence, wherein each of the other sets of values includes at least one particular value that is not included in another set of values of the sequence, wherein a quantity of values in an individual set is inversely proportional to a duration of time that corresponds to the individual set; comparing, with the one or more hardware processors, one or more values of the metric to the multiple-adjusted dynamic threshold; responsive to the comparison indicating exacerbation of a medical state of the subject, temporarily holding, with the one or more hardware processors, a current level of the multiple-adjusted dynamic threshold constant for a period of time; and providing, with the one or more hardware processors, a notification to a caregiver based on a comparison of one or more additional values of the metric with the temporarily held current level of the multiple-adjusted dynamic threshold, wherein the notification indicates an ongoing exacerbation of the medical state of the subject. - View Dependent Claims (9, 10, 11, 12, 13, 14)
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15. A system configured to detect exacerbations based on dynamically-updated threshold values, the system comprising:
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means for obtaining a sequence of values for a metric that quantifies a lung-related characteristic of a subject, each value of the sequence corresponding to a time during a defined period different from a time to which at least another value of the sequence corresponds; means for determining, based on a set of values of the sequence, a dynamic threshold for the subject; means for adjusting the dynamic threshold for the subject multiple times during the defined period based on other sets of values of the sequence, wherein each of the other sets of values includes at least one particular value that is not included in another set of values of the sequence, wherein a quantity of values in an individual set is inversely proportional to a duration of time that corresponds to the individual set; means for comparing one or more values of the metric to the multiple-adjusted dynamic threshold; responsive to the comparison indicating exacerbation of a medical state of the subject, means for temporarily holding a current level of the multiple-adjusted dynamic threshold constant for a period of time; and means for providing a notification to a caregiver based on a comparison of one or more additional values of the metric with the temporarily held current level of the multiple-adjusted dynamic threshold, wherein the notification indicates an ongoing exacerbation of the medical state of the subject. - View Dependent Claims (16, 17, 18, 19, 20)
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Specification