Fluid transfer apparatus with filtered air input

• US 10,327,991 B2
• Filed: 03/28/2017
• Issued: 06/25/2019
• Est. Priority Date: 04/12/2006
• Status: Active Grant

• Current Assignee: ICU Medical Incorporated
• Original Assignee: ICU Medical Incorporated
• Inventors: Seifert, John M., Fangrow, Thomas F., Warren, Dee E., Lopez, Dan
• Primary Examiner(s): Deak, Leslie R
• Application Number:
  US15/471,988
• Publication Number:
  US 20170196772A1
• Time in Patent Office: 819 Days
• CPC Class Codes: A61J 1/1406 Septums, pierceable membranes
• CPC Class Codes: A61J 1/1412 Containers with closing means, e.g. caps
• CPC Class Codes: A61J 1/201 having one piercing end
• CPC Class Codes: A61J 1/2048 Connecting means
• CPC Class Codes: A61J 1/2055 having gripping means
• CPC Class Codes: A61J 1/2065 having aligning and guiding means
• CPC Class Codes: A61J 1/2072 for internal venting
• CPC Class Codes: A61J 1/2075 for external venting
• CPC Class Codes: A61J 1/2079 Filtering means
• CPC Class Codes: A61J 1/2082 for gas filtration
• CPC Class Codes: A61J 1/2086 for fluid filtration
• CPC Class Codes: A61J 1/2089 Containers or vials which are to be joined to each other in order to mix their contents combinations of vial and syringe for mixing their contents A61J1/2096
• CPC Class Codes: A61J 1/2096 Combination of a vial and a syringe for transferring or mixing their contents
• CPC Class Codes: A61J 1/22 with means for metering the amount of fluid
• CPC Class Codes: A61J 2200/10 Coring prevention means, e.g. for plug or septum piecing members
• CPC Class Codes: A61J 2200/76 for fluid level
• CPC Class Codes: Y10T 137/0402 Cleaning, repairing, or assembling
• CPC Class Codes: Y10T 29/49826 Assembling or joining
• CPC Class Codes: Y10T 29/49885 with coating before or during assembling

Abstract

In certain embodiments, a vial adaptor for removing liquid contents from a vial comprises a piercing member and a bag. The bag can be contained within the piercing member such that the bag is introduced to the vial when the vial adaptor is coupled with the vial. In some embodiments, the bag expands within the vial as liquid is removed from the vial via the adaptor, thereby regulating pressure within the vial. In other embodiments, a vial comprises a bag for regulating pressure within the vial as liquid is removed therefrom. In some embodiments, a vial adaptor is coupled with the vial in order to remove the liquid. In some embodiments, as the liquid is removed from the vial via the adaptor, the bag expands within the vial, and in other embodiments, the bag contracts within the vial.

Claims

1. A device for transferring medicinal fluid between a syringe and a vial, the device comprising:

a medical connector interface configured to couple the device with the syringe to place an interior of the syringe in fluid communication with an interior of the vial;

a piercing member;

a first filter configured to be in fluid communication with the interior of the vial, wherein the first filter is configured to filter ambient air entering a regulator channel, thereby preventing dust, bacteria, microbes, spores, or other contaminants from entering the vial;

a second filter configured to prohibit passage of liquid or vapors from the regulator channel to ambient;

an insertion member movable independent of the piercing member, the insertion member comprising a regulator aperture connected to the regulator channel, the regulator channel configured to permit ambient air to flow into the regulator channel as the medicinal fluid is withdrawn from the vial, thereby equalizing pressure within the vial; and

an extractor channel configured to permit medicinal fluid to pass therethrough.

2. The device of claim 1, wherein the device is configured to allow substantially all of the medicinal fluid to be withdrawn from the vial.

3. The device of claim 1, wherein at least a portion of the extractor channel extends through the piercing member.

4. The device of claim 1, wherein the device further comprises a cap connector configured to couple the device with the vial.

5. The device of claim 1, wherein the first filter is spatially separated from the second filter.

6. The device of claim 1, wherein the first and second filters are generally parallel to one another.

7. The device of claim 1, wherein the first and second filters are hydrophobic filters.

8. The device of claim 1, wherein the second filter is configured to filter air passing between the regulator channel and ambient.

9. The device of claim 1, further comprising an input port housing the first filter.

10. The device of claim 1, further comprising a regulator port housing the second filter.

11. The device of claim 10, wherein the regulator port comprises a flexible bag in a substantially airtight engagement with the regulator port.

12. The device of claim 1, further comprising a sheath configured to define a chamber and a slot, wherein the insertion member is housed in the chamber.

13. The device of claim 12, further comprising a tab attached to the insertion member and extending through the slot in the sheath such that as the tab moves along the slot, the insertion member moves longitudinally within the chamber of the sheath.

14. The device of claim 13, wherein the slot comprises a locking mechanism configured to secure the insertion member to the device, wherein the locking mechanism comprises one or more clips connected to the sheath, the locking mechanism having a closed position and an open position, wherein in the closed position the one or more clips are adapted to secure the insertion member to the sheath, and wherein, in the open position the one or more clips are adapted not to secure the insertion member at least partially to the sheath.

15. The device of claim 14, wherein the tab is configured to force the one or more clips of the locking mechanism toward the open position when the tab is moved down the slot.

16. A method of manufacturing a device for transferring medicinal fluid between a syringe and a vial, the method comprising:

disposing a first filter and a second filter on the device, the device comprising;

a medical connector interface configured to couple with the syringe to place an interior of the syringe in fluid communication with an interior of the vial when the device is coupled with the vial;

a piercing member;

an insertion member movable independent of the piercing member, the insertion member comprising a regulator aperture connected to a regulator channel, the regulator channel configured to permit ambient air to flow into the vial to equalize pressure within the vial; and

an extractor channel configured to permit medicinal fluid to pass therethrough;

wherein the first filter is configured to be in fluid communication with the interior of the vial;

wherein the first filter is configured to filter ambient air entering the regulator channel, thereby preventing dust, bacteria, microbes, spores, or other contaminants from entering the vial; and

wherein the second filter is configured to prohibit passage of liquid or vapors from the regulator channel to ambient.

17. The method of claim 16, wherein the method further comprises coupling the device with the vial via a cap connector.

18. The method of claim 16, wherein the method further comprises positioning the first and second filters such that they are spatially separated from one another.

19. The method of claim 16, wherein the method further comprises orienting the first and second filters to be generally parallel.

20. The method of claim 16, wherein the method further comprises disposing the first filter in an input port configured to permit ambient air to enter the device and disposing the second filter in a regulator port configured to regulate pressure within the vial.