Devices and methods for modulating medium delivery

• US 10,335,539 B2
• Filed: 03/25/2016
• Issued: 07/02/2019
• Est. Priority Date: 08/28/2012
• Status: Active Grant

• Current Assignee: Osprey Medical, Inc.
• Original Assignee: Osprey Medical, Inc.
• Inventors: Burns, Matthew M., Doan, Tuan M., Houfburg, Rodney L., Kaye, David M., Mans, Daniel R., Mortier, Todd J.
• Primary Examiner(s): Osinski, Bradley J
• Assistant Examiner(s): Shah, Nilay J
• Application Number:
  US15/081,041
• Publication Number:
  US 20160310660A1
• Time in Patent Office: 1,194 Days
• CPC Class Codes: A61M 2025/0076 Unidirectional valves
• CPC Class Codes: A61M 2039/2413 designed to reduce and or shut-off the flow when a certain maximum flow limit is exceeded
• CPC Class Codes: A61M 2205/3331 Pressure; Flow
• CPC Class Codes: A61M 2205/3334 Measuring or controlling the flow rate
• CPC Class Codes: A61M 2205/3337 Controlling, regulating pressure or flow by means of a valve by-passing a pump
• CPC Class Codes: A61M 2205/3341 stabilising pressure or flow to avoid excessive variation
• CPC Class Codes: A61M 2205/3344 Measuring or controlling pressure at the body treatment site
• CPC Class Codes: A61M 2205/3355 Controlling downstream pump pressure
• CPC Class Codes: A61M 2206/22 eliminating pulsatile flows, e.g. by the provision of a dampening chamber
• CPC Class Codes: A61M 2210/125 Heart
• CPC Class Codes: A61M 2210/127 Aorta
• CPC Class Codes: A61M 25/0075 Valve means
• CPC Class Codes: A61M 39/24 Check- or non-return valves
• CPC Class Codes: A61M 5/007 for contrast media
• CPC Class Codes: A61M 5/1413 Modular systems comprising interconnecting elements
• CPC Class Codes: A61M 5/14212 Pumping with an aspiration and an expulsion action
• CPC Class Codes: A61M 5/14216 Reciprocating piston type
• CPC Class Codes: A61M 5/145 using pressurised reservoirs, e.g. pressurised by means of pistons
• CPC Class Codes: A61M 5/16881 Regulating valves on-off valves, e.g. clamps A61M39/28
• CPC Class Codes: A61M 5/48 having means for varying, regulating, indicating or limiting injection pressure A61M5/142 takes precedence ; monitoring pressure in infusion systems A61M5/16854
• CPC Class Codes: A61M 5/482 : Varying injection pressure, e.g. by varying speed of injection
• CPC Class Codes: A61M 5/484 : Regulating injection pressure
• CPC Class Codes: A61M 5/488 : Limiting injection pressure
• CPC Class Codes: F04B 11/0033 : with a mechanical spring
• CPC Class Codes: G16H 20/10 : relating to drugs or medications, e.g. for ensuring correct administration to patients
• CPC Class Codes: G16H 20/17 : delivered via infusion or injection

Abstract

Devices, systems and methods for controlling, regulating, altering, transforming or otherwise modulating the delivery of a substance to a delivery site. The devices, systems and methods optimize the delivery of the substance to an intended site, such as a vessel, vascular bed, organ and/or other corporeal structures, while reducing inadvertent introduction or reflux substance to other vessels, vascular beds, organs, and/or other structures, including systemic introduction.

Claims

1. A method for mechanically modulating a fluid medium delivered to a vascular site within a body of a patient, the method comprising:

employing a system including;

a sterile medium container that contains the fluid medium;

an injector;

a delivery catheter configured to deliver the fluid medium from outside the body of the patient to the vascular site within the body of the patient;

a chamber disposed between the injector and the delivery catheter;

a first connector, said first connector being fluidly coupled to each of the injector, the chamber, and a second connector, wherein the first connector is fluidly coupled to the chamber via a first valve;

the second connector being fluidly coupled to the sterile medium container via a second valve, and the second connector being fluidly coupled to the delivery catheter, wherein the second connector resides between the first connector and the delivery catheter;

injecting the fluid medium from the injector to the first connector, wherein the first valve is open;

simultaneously accepting a portion of the injected fluid medium into the chamber, wherein said chamber comprises at least one surface that imparts a force on the fluid medium within the chamber;

delivering the fluid medium to the vascular site within the body of the patient through the delivery catheter at a flow rate that remains substantially unchanged during the injecting of the fluid medium; and

drawing the fluid medium from the sterile medium container and filling the injector with the drawn fluid medium, wherein the first valve is closed and the second valve is open.

2. The method of claim 1, wherein said force within the chamber is produced at a constant, predetermined value.

3. The method of claim 1, wherein said injector is a syringe.

4. The method of claim 1, wherein said flow rate of the fluid medium through the delivery catheter is a function of a second force applied by the injector and the force applied by the chamber.

5. The method of claim 1, wherein the flow rate of the fluid medium delivered by the delivery catheter corresponds to a pressure range of the fluid medium within the chamber.

6. The method of claim 1, further comprising directing flow of the fluid medium from the chamber to a location other than the delivery catheter.

7. The method of claim 1, wherein the fluid medium is a contrast agent, and the flow rate of the delivered fluid medium is sufficient to opacify a blood vessel at the vascular site.