Implantable optical stimulation lead and methods of making and using

• US 10,335,607 B2
• Filed: 01/31/2017
• Issued: 07/02/2019
• Est. Priority Date: 02/05/2016
• Status: Active Grant

• Current Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Inventors: Orinski, William George
• Primary Examiner(s): Farah, Ahmed M
• Application Number:
  US15/421,001
• Publication Number:
  US 20170225007A1
• Time in Patent Office: 882 Days
• Field of Search: 607 88- 90, 607 92
• CPC Class Codes: A61N 1/05 for implantation or insertion into the body, e.g. heart electrode A61N1/06 takes precedence
• CPC Class Codes: A61N 1/36025 for treating a mental or cerebral condition
• CPC Class Codes: A61N 1/3754 Feedthroughs
• CPC Class Codes: A61N 2005/0612 using probes penetrating tissue; interstitial probes
• CPC Class Codes: A61N 2005/0651 Diodes
• CPC Class Codes: A61N 2005/0653 Organic light emitting diodes
• CPC Class Codes: A61N 5/0601 Apparatus for use inside the body
• CPC Class Codes: A61N 5/0622 Optical stimulation for exciting neural tissue
• CPC Class Codes: A61N 5/067 using laser light

Abstract

An optical stimulation lead includes a lead body including a distal end, a distal portion, and a proximal portion; and an optical assembly attached to the distal end of the lead body. The optical assembly includes a light emitter; a feedthrough assembly including at least one ceramic block, at least one feedthrough pin extending through the at least one ceramic block and electrically coupled to the light emitter, and a metal housing attached to the at least one ceramic block; a metal tube attached to the feedthrough assembly and disposed around the light emitter; and an emitter cover disposed over the light emitter and coupled to the metal tube.

Claims

1. An optical stimulation lead, comprising:

a lead body comprising a distal end, a distal portion, and a proximal portion; and

an optical assembly attached to the distal end of the lead body and comprising

a light emitter,

a feedthrough assembly comprising at least one ceramic block, at least one feedthrough pin extending through the at least one ceramic block and electrically coupled to the light emitter, and a metal housing attached to the at least one ceramic block,

a metal tube attached to the feedthrough assembly and disposed around the light emitter, and

an emitter cover disposed over the light emitter and coupled to the metal tube.

2. The optical stimulation lead of claim 1, wherein the optical assembly forms a hermetically sealed housing for the light emitter.

3. The optical stimulation lead of claim 1, wherein the optical assembly further comprises an anchor extending proximally from the feedthrough assembly, wherein the anchor is configured and arranged to be inserted into the distal end of the lead body to anchor the optical assembly to the lead body.

4. The optical stimulation lead of claim 3, wherein the anchor comprises a proximally tapered flange to facilitate attachment of the anchor to the lead body.

5. The optical stimulation lead of claim 4, wherein the lead body defines a lumen that is configured and arranged to receive at least a portion of the anchor to facilitate attachment of the anchor to the lead body.

6. The optical stimulation lead of claim 4, wherein the at least one ceramic block is attached to the anchor to form a hermetic seal.

7. The optical stimulation lead of claim 1, wherein the at least one ceramic block is attached to the metal housing to form a hermetic seal.

8. The optical stimulation lead of claim 1, wherein the at least one ceramic block is attached to the at least one feedthrough pin to form a hermetic seal.

9. The optical stimulation lead of claim 1, further comprising at least one conductive cable disposed within the optical assembly to electrically couple the at least one feedthrough pin to the light emitter.

10. The optical stimulation lead of claim 1, further comprising a plurality of terminals disposed along the proximal portion of the lead body.

11. The optical stimulation lead of claim 10, further comprising at least one electrode disposed along the distal portion of the lead body.

12. The optical stimulation lead of claim 11, wherein each of the at least one electrode is electrically coupled to at least one of the terminals.

13. The optical stimulation lead of claim 10, wherein the lead body defines a plurality of lumens extending along the lead body.

14. The optical stimulation lead of claim 1, wherein the emitter cover comprises an optical diffuser.

15. The optical stimulation lead of claim 1, wherein the emitter cover comprises a lens.

16. An optical stimulation system, comprising:

the optical stimulation lead of claim 1; and

a control module coupleable to the optical stimulation lead, the control module comprising

a housing, and

an electronic subassembly disposed in the housing and configured and arranged to provide electrical signals to the light emitter of the optical stimulation lead.

17. The optical stimulation system of claim 16, wherein the lead further comprises a plurality of terminals disposed along the proximal portion of the lead body, the optical stimulation system further comprising a connector for receiving the proximal portion of the lead body, the connector having a proximal end, a distal end, and a longitudinal length, the connector comprising

a connector housing defining a port at the distal end of the connector, the port configured and arranged for receiving the proximal portion of the lead body of the optical stimulation lead, and

a plurality of connector contacts disposed in the connector housing, the plurality of connector contacts configured and arranged to couple to the plurality of terminals disposed along the proximal portion of the lead body of the optical stimulation lead.

18. The optical stimulation system of claim 17, wherein the connector is part of the control module.

19. The optical stimulation system of claim 17, further comprising a lead extension coupleable to both the optical stimulation lead and the control module, wherein the connector is part of the lead extension.

20. A method of stimulating patient tissue, the method comprising:

implanting the optical stimulation lead of claim 1 into the patient tissue; and

emitting light from the light emitter of the optical stimulation lead to stimulate the patient tissue.