Triaxial antenna for microwave tissue ablation

• US 10,342,614 B2
• Filed: 07/31/2012
• Issued: 07/09/2019
• Est. Priority Date: 04/29/2004
• Status: Active Grant

• Current Assignee: Wisconsin Alumni Research Foundation (University of Wisconsin System)
• Original Assignee: Wisconsin Alumni Research Foundation (University of Wisconsin System)
• Inventors: van der Weide, Daniel W.
• Primary Examiner(s): Peffley, Michael F
• Assistant Examiner(s): Good, Samantha M
• Application Number:
  US13/563,050
• Publication Number:
  US 20120316551A1
• Time in Patent Office: 2,534 Days
• Field of Search: 606 32- 33
• CPC Class Codes: A61B 18/18 by applying electromagnetic radiation, e.g. microwaves radiation therapy A61N5/00
• CPC Class Codes: A61B 18/1815 using microwaves
• CPC Class Codes: A61B 2018/00023 closed, i.e. without wound contact by the fluid

Abstract

An improved antenna for microwave ablation uses a triaxial design which reduces reflected energy allowing higher power ablation and/or a smaller diameter feeder line to the antenna.

Claims

1. A system for microwave ablation for receiving a microwave frequency from a source of microwave electrical power and comprising:

a probe adapted for insertion into a human tissue, the probe comprising;

a first conductor;

a second conductor coaxially surrounding an extent of the first conductor but insulated therefrom, wherein the first and second conductors are adapted to receive electrical conductors communicating with the source of microwave electrical power; and

a third conductor coaxially surrounding an extent of the second conductor that is coaxially surrounding the extent of the first conductor;

wherein the first conductor extends beyond the second conductor by a distance of L2;

wherein the second conductor extends beyond the third conductor by a distance of L1;

and wherein L1 and L2 are each in length an odd multiple of a quarter wavelength of the microwave frequency conducted through the probe as affected by the human tissue when substantially an entire length of the probe over distance L1 and L2 is in contact with and surrounded by the human tissue and when the microwave frequency conducted through the probe is provided at a frequency of approximately 2.45 Ghz.

2. The system of claim 1, comprising a sharpened tip.

3. The system of claim 1, wherein a portion of the first conductor extending beyond the second conductor is electrically insulated.

4. The system of claim 1, wherein the third conductor has an opening smaller than fourteen gauge.

5. The system of claim 1 including a first connector for transmitting the microwave electrical power from a portion of the electrical conductors communicating with the source of microwave electrical power to a portion of the first conductor outside the human tissue and a second connector for transmitting the microwave electrical power from a portion of the electrical conductors communicating with the source of microwave electrical power to a portion of the second conductor outside the human tissue.

6. The system of claim 5, wherein the electrical conductors communicating with the source of microwave electrical power define a coaxial cable, said probe is removably attachable to the coaxial cable and is disposable.

7. The system of claim 1, wherein the source of microwave electrical power comprises a power supply connected to said first and second connector via a coaxial cable.

8. The system of claim 1, wherein only an insulating air gap is between said second conductor and said third conductor.

9. The system of claim 1, wherein said first conductor terminates at an end of the probe and wherein the distance L1 and distance L2 are selected to provide a peak electrical field at said end.

10. The system of claim 1, wherein the distance L1 and the distance L2 are selected to reduce reflected energy back to the source of microwave power.

11. The system of claim 10, wherein the distance L1 and the distance L2 are of a length to provide a reduction in reflected energy from the first conductor to the second conductor of at least ten decibels relative to a reflected energy from a coaxial monopole, and wherein the electrical conductors communicating with the source of microwave electrical power define a coaxial cable.

12. The system of claim 11, wherein the distance L1 and the distance L2 are selected to permit a region of necrosis at an ablation site of greater than two centimeters in diameter.

13. The system of claim 1, wherein the second and third conductors are adapted for percutaneous insertion into the human tissue.

14. The system of claim 1, wherein a proximal end of the third conductor comprises a sharpened tip.

15. The system of claim 14, wherein the third conductor is formed of a rigid metal.

16. A method of microwave ablation comprising the steps of:

(a) inserting a probe into a human tissue, the probe having a first conductor;

a second conductor coaxially surrounding an extent of the first conductor, but insulated therefrom; and

a third conductor coaxially surrounding an extent of the second conductor that is coaxially surrounding the extent of the first conductor, wherein the first conductor extends a length L2 from the second conductor and the second conductor extends a length L1 from the third conductor;

(b) supplying the first and second conductors with microwave electrical power from a microwave generator;

(c) tuning the probe by adjusting L1 with respect to L2 to reduce reflected power, wherein L1 and L2 are each in length an odd multiple of a quarter wavelength of a microwave frequency conducted through the probe as affected by the human tissue when substantially an entire length of the probe over distance L1 and L2 is in contact with and surrounded by the human tissue and when the microwave frequency conducted through the probe is provided at a frequency of approximately 2.45 Ghz; and

(d) providing current flow between exposed portions of the first and second conductors ablating the human tissue in a region of the exposed portions of the first and second conductors.

17. A probe for microwave ablation comprising:

a first conductor;

a tubular second conductor coaxially around the first conductor but insulated therefrom; and

a tubular third conductor coaxially around the first and second conductor;

wherein the first conductor extends beyond the second conductor into tissue, when a proximal end of the probe is inserted into a body for microwave ablation, for microwave frequency current flow between the first and second conductors through the tissue;

wherein the second conductor is surrounded by an outer insulating dielectric or an insulating air gap is provided between the second conductor and the third conductor; and

wherein

the second conductor extends beyond the third conductor into tissue when an end of the probe is inserted into the body for microwave ablation to provide improved tuning of the probe limiting power dissipated in the probe outside of exposed portions of the first and second conductors; and

the first conductor extends beyond the second conductor by a distance of L2 and the second conductor extends beyond the third conductor by a distance of L1 wherein L1 and L2 are odd multiples of a quarter wavelength of a microwave frequency that the probe is configured to receive.

18. The probe of claim 17 wherein the tubular third conductor is a needle for insertion into the body.

19. The probe of claim 18 wherein the needle has a sharpened tip.

20. The probe of claim 18 including an introducer removably received by the tubular third conductor to assist in penetration of the body by the needle.

21. The probe of claim 17 wherein the third conductor is stainless steel.

22. The probe of claim 17 wherein the first and second conductors fit slidably within the third conductor.

23. The probe of claim 22 further including a lock attached to the third conductor to adjustably lock a sliding location of the first and second conductors with respect to the third conductor.

24. The probe of claim 22 further including a first stop attached to the first and second conductors to about a second stop attached to the third conductor to set an amount the second conductor extends beyond the tubular third conductor into tissue.

25. The probe of claim 24 wherein the first stop is adjustable.

26. The probe of claim 17 wherein the first conductor extends beyond the second conductor by L2 and the second conductor extends beyond the third conductor by L1 wherein L1 equals L2.

27. The probe of claim 17 wherein a portion of the first conductor extending beyond the second conductor is electrically insulated.

28. The probe of claim 17 wherein the third conductor has an opening smaller than 2.108 millimeters (fourteen gauge).

29. The probe of claim 17 including a connector for applying a source of microwave energy to a portion of the probe outside the body.

30. The probe of claim 17, wherein the second conductor extends beyond the third conductor by L1, wherein L1 is selected so as to enforce a zero electrical field boundary condition at a proximal end of the second conductor.