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Pharmaceutical compositions having improved storage stability

  • US 10,342,877 B2
  • Filed: 09/14/2017
  • Issued: 07/09/2019
  • Est. Priority Date: 09/19/2012
  • Status: Active Grant
First Claim
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1. A method for the preparation of an aqueous pharmaceutical composition comprising a hydrolytically labile antipsychotic agent, wherein the method comprises adding to a composition comprising the antipsychotic agent and an aqueous vehicle (a) a stabilizing amount of a non-ionic water insoluble and/or immiscible ester co-surfactant and (b) a water miscible and/or soluble non-ionic surfactant.

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