Respiratory assistance device and method of controlling said device

• US 10,342,942 B2
• Filed: 03/14/2014
• Issued: 07/09/2019
• Est. Priority Date: 03/15/2013
• Status: Active Grant

• Current Assignee: Fisher & Paykel Healthcare Limited
• Original Assignee: Fisher & Paykel Healthcare Limited
• Inventors: Tatkov, Stanislav, O'Donnell, Kevin Peter
• Primary Examiner(s): Douglas, Steven O
• Application Number:
  US14/776,994
• Publication Number:
  US 20160030690A1
• Time in Patent Office: 1,943 Days
• CPC Class Codes: A61M 15/009 using medicine packages with incorporated spraying means, e.g. aerosol cans pocket atomiser of the injector type A61M11/08
• CPC Class Codes: A61M 16/0003 Accessories therefor, e.g. sensors, vibrators, negative pressure
• CPC Class Codes: A61M 16/0069 the speed thereof being controlled by respiratory parameters, e.g. by inhalation
• CPC Class Codes: A61M 16/024 including calculation means, e.g. using a processor
• CPC Class Codes: A61M 16/0666 Nasal cannulas or tubing devices for improving normal breathing through the nose A61F5/08; nose filters A62B23/06; outside holding devices A61M25/02
• CPC Class Codes: A61M 16/0875 Connecting tubes
• CPC Class Codes: A61M 16/1015 using a gas flush valve, e.g. oxygen flush valve
• CPC Class Codes: A61M 16/104 specially adapted for anaesthetics A61M16/18 takes precedence
• CPC Class Codes: A61M 16/12 by mixing different gases
• CPC Class Codes: A61M 16/122 with dilution
• CPC Class Codes: A61M 16/16 Devices to humidify the respiration air A61M16/1045 takes precedence
• CPC Class Codes: A61M 2016/0027 pressure meter
• CPC Class Codes: A61M 2016/003 with a flowmeter
• CPC Class Codes: A61M 2016/0039 in the inspiratory circuit
• CPC Class Codes: A61M 2202/0208 Oxygen
• CPC Class Codes: A61M 2202/0225 Carbon oxides, e.g. Carbon dioxide
• CPC Class Codes: A61M 2202/0241 Anaesthetics; Analgesics
• CPC Class Codes: A61M 2205/3334 Measuring or controlling the flow rate

Abstract

A method of controlling a flow rate of gases supplied to a patient by a respiratory assistance device includes controlling the supply gases flow rate so as to deliver gases to the patient according to a predetermined gases pressure/flow rate profile for at least a portion of the breathing cycle. A profile may be achieved that provides the patient with a particular benefit or therapy.

Claims

1. A method of controlling a flow rate of respiratory gases supplied to a patient by a respiratory assistance device configured to be in fluid communication with an inspiratory conduit and a patient interface to deliver gases to the patient, and configured to be in fluid communication with a respiratory gases source, the method comprising:

controlling the flow rate of respiratory gases supplied to the patient according to a first predetermined gases pressure/flow rate profile in a first mode defined for at least a portion of a breathing cycle of the patient;

controlling the flow rate of respiratory gases supplied to the patient according to a second predetermined gases pressure/flow rate profile in a second mode for at least a portion of the breathing cycle of the patient, wherein the second predetermined gases pressure/flow rate profile is different to the first predetermined gases pressure/flow rate profile; and

controlling the flow rate of respiratory gases supplied to the patient according to at least one further predetermined gases pressure/flow rate profile in at least one further mode for at least a portion of the breathing cycle of the patient, wherein the at least one further predetermined gases pressure/flow rate profile is configured to alter the flow rate at an end of expiration and/or a beginning of inspiration to increase clearance of anatomical dead space in the patient and wherein the at least one further predetermined gases pressure/flow rate profile is configured to alter the flow rate such that the flow rate decreases to a flow rate higher than the second predetermined gases pressure/flow rate profile at an end of the at least one further predetermined gases pressure/flow rate profile.

2. The method of claim 1 wherein the further predetermined gases pressure/flow rate profile occurs between inspiration and expiration.

3. The method of claim 1 wherein at least one of the first, second and further predetermined gases pressure/flow rate profile is configured to achieve at least one of a plurality of predetermined physiological effects or benefits to the patient, which plurality of predetermined physiological effects or benefits to the patient include at least one of:

an increase in inspiratory pressure to reduce inspiratory resistance;

an increase or decrease in expiratory resistance;

an increase in the flow rate of respiratory gases supplied to the patient at the end of expiration and/or beginning of inspiration to increase clearance of anatomical dead space independently of inspiratory and/or expiratory pressure;

or

an increase in the flow rate of respiratory gases supplied to the patient to meet peak inspiratory demand independently of generated pressure during inspiration and/or expiration to accurately deliver oxygen or other respiratory or anaesthetic gases, aerosols, or humidity.

4. The method of claim 1 wherein, during one or more of the first, second and further modes, the flow rate of respiratory gases supplied to the patient is controlled such that the respiratory gases are supplied at either (1) a substantially constant pressure for at least a predetermined portion of the breathing cycle or (2) varying pressures for at least a predetermined portion of the breathing cycle.

5. The method of claim 1 wherein one or more of the first, second and further predetermined gases pressure/flow rate profile meets one or more of the following criteria:

(1) is configured to provide a supply of gas tailored to the patient'"'"'s respiratory needs at one or more points in the breathing cycle;

(2) is determined in dependence upon providing a desired pressure characteristic to the patient;

(3) is determined on the basis of the pressure in the airway of the patient;

(4) is configured such that the pressure of the respiratory gases supplied to the patient always equals or exceeds the pressure required by the patient; and

(5) is determined in dependence upon providing a desired therapeutic effect to the patient.

6. The method of claim 1 wherein the first predetermined gases pressure/flow rate profile corresponds to an inspiration mode or the second predetermined gases pressure/flow rate profile corresponds to an expiration mode.

7. The method of claim 1 wherein the flow rate of respiratory gases supplied to the patient is between about 1 and 80 L/min.

8. The method of claim 1 wherein the controlling comprises dynamically controlling the flow rate of respiratory gases supplied to the patient over time.

9. The method of claim 1 wherein the controlling comprises varying at least one of:

an impedance of a gases flow path between the respiratory gases source and a patient interface through use of a valve or flow restrictor; and

a flow rate of respiratory gases in the gases flow path.

10. The method of claim 1 wherein varying the flow rate of respiratory gases is achieved by controlling a speed of a motor of a gases flow generator that is configured to be in fluid communication with the respiratory gases source.

11. The method of claim 1 wherein pressure is determined by calculation from at least one of:

a pressure measured by a pressure sensor;

a flow rate measured by a flow sensor;

a motor speed; and

a known pressure drop.

13. The method of claim 1 further comprising supplying the flow of respiratory gases to the patient through a nasal high flow or jet delivery system.

14. The method of claim 1 wherein the at least one further predetermined gases pressure/flow rate profile is configured to increase the flow rate at the end of expiration and/or the beginning of inspiration to flush anatomical dead space.

21. The method of claim 1 wherein the first predetermined gases pressure/flow rate profile corresponds to an inspiration mode and the second predetermined gases pressure/flow rate profile corresponds to an expiration mode.

12. A respiratory assistance device configured to be in fluid communication with an inspiratory conduit and a patient interface to deliver gases to a patient, and configured to be in fluid communication with a respiratory gases source, the respiratory assistance device comprising:

a controller operative to control a flow rate of respiratory gases supplied to the patient according to a first predetermined gases pressure/flow rate profile in a first mode defined for at least a portion of a breathing cycle of the patient;

the controller operative to control a flow rate of respiratory gases supplied to the patient according to a second predetermined gases pressure/flow rate profile in a second mode for at least a portion of the breathing cycle of the patient, wherein the second predetermined gases pressure/flow rate profile is different to the first predetermined gases pressure/flow rate profile; and

the controller operative to control a flow rate of respiratory gases supplied to the patient according to at least one further predetermined gases pressure/flow rate profile in at least one further mode for at least a portion of the breathing cycle of the patient, wherein the at least one further predetermined gases pressure/flow rate profile is configured to alter the flow rate at an end of expiration and/or a beginning of inspiration to increase clearance of anatomical dead space in the patient and wherein the at least one further predetermined gases pressure/flow rate profile is configured to alter the flow rate such that the flow rate decreases to a flow rate higher than the second predetermined gases pressure/flow rate profile at an end of the at least one further predetermined gases pressure/flow rate profile.

17. The respiratory assistance device of claim 12 further comprising supplying the flow of respiratory gases to the patient through a nasal high flow or jet delivery system.

18. The respiratory assistance device of claim 12 wherein the at least one further predetermined gases pressure/flow rate profile is configured to increase the flow rate at the end of expiration and/or the beginning of inspiration to flush anatomical dead space.

19. The respiratory assistance device of claim 18, wherein the at least one further predetermined gases pressure/flow rate profile is further configured to, following increasing the flow at the end of expiration and/or the beginning of inspiration, immediately reduce the flow rate to a level no less than 10 L/min.

20. The respiratory assistance device of claim 18, wherein the at least one further predetermined gases pressure/flow rate profile is further configured to, following increasing the flow rate at the end of expiration and/or the beginning of inspiration, immediately reduce the flow rate to a level that meets, or is in excess of, peak inspiratory demand.

15. The method of 14, wherein the at least one further predetermined gases pressure/flow rate profile is further configured to, following increasing the flow at the end of expiration and/or the beginning of inspiration, immediately reduce the flow rate to a level no less than 10 L/min.

16. The method of 14, wherein the at least one predetermined gases pressure/flow rate profile is further configured to, following increasing the flow at the end of expiration and/or beginning of inspiration, immediately reduce flow to a level that meets, or is in excess of, peak inspiratory demand.