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Methods and systems for delivering substances into luminal walls

  • US 10,342,960 B2
  • Filed: 02/13/2017
  • Issued: 07/09/2019
  • Est. Priority Date: 05/11/2005
  • Status: Active Grant
First Claim
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1. A method for delivering an active substance to a luminal site, the method comprising:

  • providing a device comprising;

    a catheter body having a proximal end and a distal end;

    an expandable shell;

    a scoring structure having a proximal end and a distal end, comprising at least one scoring element disposed near the distal end of the catheter body and over the expandable shell, wherein one of the proximal end and the distal end of the scoring structure is fixed to the catheter body and the other of the proximal end and the distal end of the scoring structure is axially slidable with respect to the expandable shell;

    an active substance carried by the at least one scoring element;

    positioning the at least one scoring element within a body lumen; and

    expanding the expandable shell to cause movement of the at least one scoring element, the at least one scoring element thereby penetrating an occlusion at the luminal site within the body lumen, the active substance being released from the at least one scoring element into the occlusion at the luminal site as a result of the penetration.

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