Micro-charge stimulation

• US 10,342,975 B2
• Filed: 05/18/2016
• Issued: 07/09/2019
• Est. Priority Date: 09/14/2015
• Status: Active Grant

• Current Assignee: Cochlear Limited
• Original Assignee: Cochlear Limited
• Inventors: Ridler, Oliver John, Carter, Paul Michael
• Primary Examiner(s): Wu, Eugene T
• Application Number:
  US15/158,120
• Publication Number:
  US 20170072196A1
• Time in Patent Office: 1,147 Days
• CPC Class Codes: A61N 1/36038 Cochlear stimulation

Abstract

Presented herein are stimulation techniques for implantable tissue-stimulating systems. The stimulation techniques generate and deliver sets of micro-charge pulses to a recipient. The micro-charge pulses within a set collectively cause the firing of a recipient'"'"'s nerve cell(s).

Claims

1. A method, comprising:

receiving one or more sound signals via at least one sound input element of a stimulating auditory system implanted in a recipient; and

at a sound processor of the stimulating auditory system, generating processed sound signals representative of the one or more sound signals;

at a stimulator unit of the stimulating auditory system, generating, based on the processed sound signals, a first set of positive polarity micro-charge pulses;

delivering the first set of positive polarity micro-charge pulses in sequence to a group of nerve cells of the recipient via a single stimulation channel, wherein the first set of positive polarity micro-charge pulses collectively evoke perception of at least a portion of the processed sound signals, wherein each micro-charge pulse is generated by the discharge of a single capacitor having a sufficiently small size such that each micro-charge pulse in the first set of micro-charge pulses is delivered at a peak current that delivers insufficient charge alone to activate the group of nerve cells;

at the stimulator unit, generating a second set of micro-charge pulses each having a negative polarity; and

following delivery of the first set of micro-charge pulses, delivering the second set of negative polarity micro-charge pulses in sequence to the group of nerve cells of the recipient to withdraw a charge associated with the first set of micro-charge pulses from the group of nerve cells.

2. The method of claim 1, wherein generating the first set of micro-charge pulses comprises:

generating the micro-pulses with time durations and at a frequency to cause the recipient to perceive an average over time of a total integral current of the set of micro-charge pulses.

3. The method of claim 1, further comprising:

generating each micro-charge pulse in the first set of micro-charge pulses with a switched capacitor circuit formed by a plurality of switches configured to be selectively activated to connect first and second sides of the capacitor to at least one of a supply voltage and a ground.

4. The method of claim 3, wherein the stimulating auditory system comprises a plurality of stimulation channels terminating in one or more stimulating contacts, and wherein the method further comprises:

delivering each micro-charge pulse in the set of micro-charge pulses to the group of nerve cells via at least one switching circuit connected between the capacitor and at least one stimulating contact.

5. The method of claim 4, further comprising:

monitoring a voltage at an output of the switching circuit; and

determining, based on the voltage at the output of the switching circuit, when a predetermined amount of charge has been delivered by a micro-charge pulse; and

opening the switching circuit when the predetermined amount of charge has been delivered by the micro-charge pulse.

6. The method of claim 1, wherein the stimulating auditory system comprises a plurality of stimulation channels each terminating in one or more stimulating contacts.

7. The method of claim 6, wherein the first set of micro-charge pulses represent a first portion of the one or more sound signals, and wherein the method further comprises:

delivering the first set of micro-charge pulses to the recipient via a first stimulation channel to evoke perception of the first portion of the one or more sound signals;

generating a third set of micro-charge pulses representative of a second portion of the one or more sound signals; and

delivering the third set of micro-charge pulses to the recipient via a second stimulation channel to evoke perception of the second portion of the one or more sound signals.

8. The method of claim 7, further comprising:

varying between the first and third sets of micro-charge pulses one or more of the number of micro-charge pulses in a set, the time length of each micro-charge pulse in a set, and an initial charge voltage of each micro-charge pulse in a set.

9. A method, comprising:

generating, at a sound processor of a stimulating auditory system, processed sound signals;

generating, at a micro-charge pulse injection circuit implanted in a recipient, a first plurality of micro-charge pulses based on the processed sound signals;

delivering, via a switching circuit implanted in the recipient, the first plurality of micro-charge pulses to a group of nerve cells of the recipient in sequence via a stimulation channel so as to evoke perception of at least a portion of the processed sound signals, wherein each of the first plurality of micro-charge pulses has a first polarity and is generated by the discharge of a single capacitor having a sufficiently small size such that each micro-charge pulse delivers insufficient charge alone to activate the group of nerve cells;

generating, at the micro-charge pulse injection circuit implanted in a recipient, a second plurality of micro-charge pulses; and

following delivery of the first plurality of micro-charge pulses, delivering, via the switching circuit implanted in the recipient, the second plurality of micro-charge pulses to the group of nerve cells of the recipient in sequence to withdraw a charge associated with the first plurality of micro-charge pulses from the group of nerve cells.

10. The method of claim 9, wherein generating the first plurality of micro-charge pulses comprises:

generating the first plurality of micro-pulses with time durations and at a frequency to cause the recipient to perceive an average over time of a total integral current of the set of micro-charge pulses.

11. The method of claim 9, wherein the micro-charge pulse injection circuit comprises a switched capacitor circuit formed by a plurality of switches configured to be selectively activated to connect first and second sides of the capacitor to at least one of a supply voltage and a ground.

12. The method of claim 9, further comprising:

monitoring a voltage at an output of the switching circuit; and

determining, based on the voltage at the output of the switching circuit, when a predetermined amount of charge has been delivered by at least one micro-charge pulse in the first plurality of micro-charge pulses; and

opening the switching circuit when the predetermined amount of charge has been delivered by the at least one micro-charge pulse.

13. The method of claim 9, wherein the stimulating auditory system comprises a plurality of stimulation channels each terminating in one or more stimulating contacts.

14. The method of claim 13, wherein the first plurality of micro-charge pulses are representative of a first portion of the processed sound signals, and wherein the method further comprises:

generating a third plurality of micro-charge pulses representative of a second of the processed sound signals;

delivering the first plurality of micro-charge pulses to the recipient via a first stimulation channel to evoke perception of the first portion of the one or more sound signals; and

delivering the third plurality of micro-charge pulses to the recipient via a second stimulation channel to evoke perception of the second portion of the one or more sound signals.

15. The method of claim 14, further comprising:

varying between the first and third plurality of micro-charge pulses one or more of the number of micro-charge pulses, the time length of each micro-charge pulse, and an initial charge voltage of each micro-charge pulse.

16. The method of claim 13, delivering both the first and second plurality of micro-charge pulses to the group of nerve cells via a single stimulation channel.

17. A stimulating auditory system, comprising:

at least one sound input element configured to receive one or more sound signals;

a sound processor configured to generate processed sound signals representative of the one or more sound signals; and

an implantable stimulator unit configured to;

generate, based on the processed sound signals, a first set of micro-charge pulses each having a positive polarity;

deliver the first set of micro-charge pulses to a group nerve cells of a recipient via a single stimulation channel, wherein the first set of micro-charge pulses collectively activate the group of nerve cells to evoke perception of a portion of the processed sound signals, and wherein each micro-charge pulse is generated by the discharge of a single capacitor having a sufficiently small size such that each micro-charge pulse in the first set of micro-charge pulses delivers insufficient charge alone to activate the group of nerve cells;

generate a second set of micro-charge pulses each having a negative polarity; and

following delivery of the first set of micro-charge pulses, deliver the second set of micro-charge pulses to the recipient to collectively withdraw a charge associated with the first set of micro-charge pulses from the group of nerve cells.

18. The stimulating auditory system of claim 17, wherein the stimulator unit comprises:

at least one micro-charge pulse injection circuit that includes a plurality of switches configured to be selectively activated to connect first and second sides of the capacitor to at least one of a supply voltage and a ground;

a controller configured to actuate the plurality of switches to selectively connect the first and second sides of the capacitor to at least one of the supply voltage and the ground to generate each of the micro-charge pulses in the first and second sets of micro-charge pulses; and

an output switching circuit configured to connect the at least one micro-charge pulse injection circuit to one or more stimulating contacts.

19. The stimulating auditory system of claim 18, wherein the at least one micro-charge pulse injection circuit comprises:

at least one comparator having a first input connected to an output of the output switching circuit such that the first input of the comparator has an input value that is the same as the voltage at the output of the output switching circuit; and

at least one digital-to-analog converter (DAC) configured to apply a predetermined voltage to a second input of the comparator,

wherein the comparator is configured to open the switching circuit when the voltage at the output of the output switching circuit is equal to the predetermined voltage.

20. The stimulating auditory system of claim 18, wherein the at least one micro-charge pulse injection circuit comprises a plurality of micro-charge pulse injection circuits that each includes a respective plurality of switches configured to be selectively activated to connect first and second sides of one or more capacitors to at least one of the supply voltage and the ground.

21. The stimulating auditory system of claim 17, further comprising a plurality of stimulating contacts configured to be positioned adjacent to nerve cells.