Methods and systems for treating cardiac malfunction
First Claim
1. A system for treating cardiac malfunction, comprising:
- a stimulation circuit configured to deliver a stimulation pulse to at least one cardiac chamber of a heart of a patient; and
at least one controller configured to execute delivery of a stimulation pattern of stimulation pulses to the at least one cardiac chamber over a time period of at least three months,wherein at least one of the stimulation pulses has a first stimulation setting configured to reduce end diastolic volume (EDV) in the heart of the patient and at least one of the stimulation pulses has a second stimulation setting different from the first stimulation setting, andwherein the stimulation pattern is configured to;
reduce, during the time period of at least three months, the end diastolic volume (EDV) by at least 5%,maintain, during the time period of at least three months, the end diastolic volume (EDV) in the heart of the patient on average at such reduced volume, andmaintain, during the time period of at least three months, blood pressure of the patient within an average pressure of ±
10% as compared to a pretreatment blood pressure value.
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Accused Products
Abstract
Methods and systems for treating cardiac malfunction are disclosed, which according to an embodiment, may involve delivering a stimulation pattern of stimulation pulses to at least one cardiac chamber of a heart, with at least one of the stimulation pulses having a first stimulation setting configured to reduce at least one of end systolic volume (ESV) and end diastolic volume (EDV) in the heart and at least one of the stimulation pulses having a second stimulation setting different from the first stimulation setting, and with the stimulation pattern being configured to reduce the at least one of end systolic volume (ESV) and end diastolic volume (EDV) by at least 5% and maintain the at least one of end systolic volume (ESV) and end diastolic volume (EDV) on average at such reduced volume for a time period of at least one hour.
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Citations
30 Claims
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1. A system for treating cardiac malfunction, comprising:
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a stimulation circuit configured to deliver a stimulation pulse to at least one cardiac chamber of a heart of a patient; and at least one controller configured to execute delivery of a stimulation pattern of stimulation pulses to the at least one cardiac chamber over a time period of at least three months, wherein at least one of the stimulation pulses has a first stimulation setting configured to reduce end diastolic volume (EDV) in the heart of the patient and at least one of the stimulation pulses has a second stimulation setting different from the first stimulation setting, and wherein the stimulation pattern is configured to; reduce, during the time period of at least three months, the end diastolic volume (EDV) by at least 5%, maintain, during the time period of at least three months, the end diastolic volume (EDV) in the heart of the patient on average at such reduced volume, and maintain, during the time period of at least three months, blood pressure of the patient within an average pressure of ±
10% as compared to a pretreatment blood pressure value. - View Dependent Claims (2, 3, 4)
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5. A method for treating cardiac malfunction, comprising:
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delivering over a time period of at least three months a stimulation pattern of stimulation pulses to at least one cardiac chamber of a heart of a patient, wherein at least one of the stimulation pulses has a first stimulation setting configured to reduce end diastolic volume (EDV) in the heart of the patient and at least one of the stimulation pulses has a second stimulation setting different from the first stimulation setting; reducing, by delivery of the stimulation pattern over the time period of at least three months, the end diastolic volume (EDV) by at least 5%, maintaining, by delivery of the stimulation pattern over the time period of at least three months, the end diastolic volume (EDV) in the heart of the patient on average at such reduced volume for the time period of at least three months, and maintaining, by delivery of the stimulation pattern over the time period of at least three months, blood pressure of the patient within an average pressure of ±
10% as compared to a pretreatment blood pressure value for the time period of at least three months. - View Dependent Claims (6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29)
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30. A method for treating cardiac malfunction, comprising:
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delivering over a time period of at least twenty-four months a stimulation pattern of stimulation pulses to at least one cardiac chamber of a heart of a patient, wherein at least one of the stimulation pulses has a first stimulation setting that stimulates a ventricle of the heart 40-90 milliseconds after atrial activation and reduces end diastolic volume (EDV) in the heart of the patient, wherein at least one of the stimulation pulses has a second stimulation setting that stimulates the ventricle 100-180 milliseconds after atrial activation, and wherein the stimulation pattern includes at least 4 consecutive heartbeats having the first stimulation setting for every 1 consecutive heartbeat having the second stimulation setting, such that the stimulation pattern; reduces, during the time period, the end diastolic volume (EDV) by an average of at least 5%, maintains, during the time period, the end diastolic volume (EDV) in the heart of the patient on average at such reduced volume, and maintains, during the time period, blood pressure of the patient within an average pressure of ±
10% as compared to a pretreatment blood pressure value.
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Specification