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Genetically encoded biosensors

  • US 10,345,297 B2
  • Filed: 08/24/2018
  • Issued: 07/09/2019
  • Est. Priority Date: 10/07/2011
  • Status: Active Grant
First Claim
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1. A recombinant peptide biosensor comprising an analyte-binding framework portion and a signaling portion, wherein the signaling portion is present within the framework portion at a site or amino acid position that undergoes a conformational change upon interaction of the framework portion with a defined, specific, or selected analyte, wherein the recombinant peptide biosensor comprises an amino acid sequence having at least 85% identity to a sequence selected from the group consisting of SEQ ID NO:

  • 77 and 78.

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