Electrochemical sensor having symmetrically distributed analyte sensitive areas
First Claim
1. An electrochemical sensor for in vivo use, comprising:
- a substrate;
a working electrode formed on or in the substrate and having multiple working electrode areas exposed for contact with a body fluid;
a second electrode formed on or in the substrate and having at least one second electrode area exposed for contact with a body fluid; and
the multiple working electrode areas and the at least one second electrode area comprising a symmetrical arrangement.
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Abstract
The present invention provides an electrochemical sensor that employs multiple electrode areas that are exposed for contact with a body fluid, e.g., when the sensor is inserted subcutaneously into a patient'"'"'s skin. The exposed electrode areas are arranged symmetrically, such that a symmetrical potential distribution is produced when an AC signal is applied to the sensor. The sensors in accordance with these teachings can advantageously be used with AC signals to determine characteristics of the sensor and thus improve sensor performance. These teachings also provide a biocompatible sensor with multiple reference electrode areas that are exposed for contact with body fluid.
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Citations
18 Claims
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1. An electrochemical sensor for in vivo use, comprising:
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a substrate; a working electrode formed on or in the substrate and having multiple working electrode areas exposed for contact with a body fluid; a second electrode formed on or in the substrate and having at least one second electrode area exposed for contact with a body fluid; and the multiple working electrode areas and the at least one second electrode area comprising a symmetrical arrangement. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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13. A method of applying AC signals to an in vivo electrochemical sensor, the sensor having a substrate, a working electrode formed on or in the substrate and a second electrode formed on or in the substrate, the method comprising:
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contacting the in vivo sensor with a body fluid, wherein multiple exposed areas of the working electrode contact the body fluid and wherein at least one exposed area of the second electrode contacts the body fluid; applying an AC signal to the sensor; and using the AC signal to correct for changes in membrane permeability, sensor sensitivity drift, sensor offset drift, or to provide fail safes for sensor performance. - View Dependent Claims (14, 15, 16, 17, 18)
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Specification