Atherectomy catheters with longitudinally displaceable drive shafts

• US 10,349,974 B2
• Filed: 05/23/2016
• Issued: 07/16/2019
• Est. Priority Date: 07/01/2010
• Status: Active Grant

• Current Assignee: Avinger Inc.
• Original Assignee: Avinger Inc.
• Inventors: Patel, Himanshu N., Simpson, John B., McNall, Charles W., Spencer, Maegan K., Zung, Michael, Gupta, Priyanshu
• Primary Examiner(s): Holwerda, Kathleen S
• Assistant Examiner(s): Simpson, Sarah A
• Application Number:
  US15/162,330
• Publication Number:
  US 20160262791A1
• Time in Patent Office: 1,149 Days
• CPC Class Codes: A61B 1/00165 with light-conductive means, e.g. fibre optics A61B1/07 takes precedence
• CPC Class Codes: A61B 1/00179 for off-axis viewing
• CPC Class Codes: A61B 1/00183 for variable viewing angles
• CPC Class Codes: A61B 1/3137 for examination of the interior of blood vessels
• CPC Class Codes: A61B 17/320725 with radially expandable cutting or abrading elements A61B17/32075 takes precedence
• CPC Class Codes: A61B 17/320758 with a rotating cutting instrument, e.g. motor driven A61B17/320725, A61B17/32075 and A61B17/320783 take precedence; for removing intra-ocular material A61F9/00763; endoscopic rotatable cutting instruments A61B17/32002
• CPC Class Codes: A61B 17/320783 through side-hole, e.g. sliding or rotating cutter inside catheter
• CPC Class Codes: A61B 2017/00292 mounted on or guided by flexible, e.g. catheter-like, means
• CPC Class Codes: A61B 2017/320791 with cutter extending outside the cutting window
• CPC Class Codes: A61B 2090/3614 using optical fibre
• CPC Class Codes: A61B 2090/3735 Optical coherence tomography [OCT]
• CPC Class Codes: A61B 5/0066 Optical coherence imaging
• CPC Class Codes: A61B 90/37 Surgical systems with images on a monitor during operation

Abstract

Described herein are atherectomy catheters, systems and methods that include longitudinally displaceable drive shafts that drive actuation of one or more cutters at the distal end of the catheter. The catheters described herein may include one or more imaging sensors for imaging before, during or after cutting tissue. In some variations the imaging sensor may be rotated around the perimeter of the catheter independently of the rotation of the cutter. Also describe herein are imaging catheters that may be used without cutters.

Claims

1. An atherectomy catheter device configured to visualize and to cut tissue, the device comprising:

an elongate catheter body;

a cutter having a distal cutting edge, the cutter configured to rotate relative to the elongate catheter body;

a cutter drive shaft within the elongate catheter body and configured to rotate the cutter;

a distal tip attached to the elongate catheter body at a hinge point, the distal tip configured to collect tissue cut by the cutter; and

an optical fiber extending a length of the elongate catheter body within the cutter drive shaft, a distal end of the optical fiber attached to the cutter and configured to rotate therewith;

wherein the cutter drive shaft is further configured to be longitudinally displaced to deflect the distal tip at the hinge point to expose the distal cutting edge of the cutter.

2. The atherectomy catheter device of claim 1, further comprising a tissue packing mechanism configured to secure tissue within the distal tip.

3. The atherectomy catheter of claim 2, wherein the tissue packing mechanism is a plunger mechanism.

4. The atherectomy catheter of claim 1, wherein in the optical fiber is part of an optical coherence tomography (OCT) imaging system.

5. The atherectomy catheter of claim 1, wherein the cutter comprises a ring cutter.

6. The atherectomy catheter of claim 1, wherein the distal cutting edge is serrated.

7. The atherectomy catheter of claim 1, wherein a least a portion of the distal tip is configured to be removable from the elongate catheter body.

8. The atherectomy catheter of claim 7, further comprising a locking mechanism configured to releaseably secure the portion of the distal tip to the elongate catheter body.

9. The atherectomy catheter of claim 1, wherein deflecting the distal tip at the hinge point causes the distal tip to move off-axis relative to the elongate catheter body.

10. The atherectomy catheter of claim 1, further comprising a mirror to deflect light from the distal end of the optical fiber into the tissue.

11. The atherectomy catheter of claim 1, further comprising one or more viewports aligned with the distal end of the optical fiber for imaging therethrough.

12. The atherectomy catheter of claim 11, wherein the viewports are separated into discrete regions, and wherein separators between the viewports are configured to act as fiduciary markers during imaging.

13. The atherectomy catheter of claim 1, wherein the cutter drive shaft is configured to rotate the cutter at between about 200 and 5,000 RPM.

14. The atherectomy catheter of claim 1, wherein the distal tip is tapered.

15. The atherectomy catheter of claim 1, wherein the distal tip is at least partially transparent.