In situ adjustable optical mask

• US 10,350,058 B2
• Filed: 02/17/2017
• Issued: 07/16/2019
• Est. Priority Date: 03/13/2013
• Status: Active Grant

• Current Assignee: Acufocus, Inc. (Bausch Health Cos., Inc.)
• Original Assignee: Acufocus, Inc. (Bausch Health Cos., Inc.)
• Inventors: Silvestrini, Thomas A.
• Primary Examiner(s): Willse, David H
• Assistant Examiner(s): Shipmon, Tiffany P
• Application Number:
  US15/436,150
• Publication Number:
  US 20170156850A1
• Time in Patent Office: 879 Days
• CPC Class Codes: A61F 2/14 Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
• CPC Class Codes: A61F 2/15 Implant having one or more holes, e.g. for nutrient transport, for facilitating handling
• CPC Class Codes: A61F 2/1659 having variable absorption coefficient for electromagnetic radiation, e.g. photochromic lenses
• CPC Class Codes: A61F 2002/1696 Having structure for blocking or reducing amount of light transmitted, e.g. glare reduction
• CPC Class Codes: G02C 7/046 Contact lenses having an iris pattern
• CPC Class Codes: G02F 1/009 Thermal properties
• CPC Class Codes: G02F 1/0126 Opto-optical modulation, i.e. control of one light beam by another light beam, not otherwise provided for in this subclass
• CPC Class Codes: G02F 1/0147 based on thermo-optic effects G02F1/132 takes precedence
• CPC Class Codes: G02F 2202/022 polymeric
• CPC Class Codes: G02F 2202/08 glass transition temperature
• CPC Class Codes: G02F 2202/14 photochromic
• CPC Class Codes: G02F 2203/48 Variable attenuator
• CPC Class Codes: G03C 1/73 containing organic compounds
• CPC Class Codes: G03C 1/733 with macromolecular compounds as photosensitive substances, e.g. photochromic photodegradable or photocrosslinkable compositions G03F7/004

Abstract

Implantable corneal and intraocular implants such as a mask are provided. The mask can improve the vision of a patient, such as by being configured to increase the depth of focus of an eye of a patient. The mask can include an aperture configured to transmit along an optical axis substantially all visible incident light. The mask can further include a transition portion that surrounds at least a portion of the aperture. This portion can be configured to switch from one level of opacity to another level of opacity through the use of a controllably variable absorbance feature such as a switchable photochromic chromophore within a polymer matrix.

Claims

1. An ophthalmic device, comprising:

an intraocular mask comprising an aperture configured to transmit substantially all visible light along the optical axis of the eye, the aperture configured to switch between a first size and a second size in response to application of an external stimulus; and

wherein the aperture is configured to remain locked into the second size after removal of the external stimulus until another application of the external stimulus, the aperture then returning to the first size.

2. The ophthalmic device of claim 1, further comprising an intraocular lens coupled to the intraocular mask.

3. The ophthalmic device of claim 1, wherein the intraocular mask comprises a plurality of photochromic chromophores within a polymer matrix.

4. The ophthalmic device of claim 3, wherein the plurality of photochromic chromophores are distributed homogenously.

5. The ophthalmic device of claim 3, wherein the plurality of photochromic chromophores are distributed heterogeneously.

6. The ophthalmic device of claim 3, wherein the concentration of photochromic chromophores varies within the polymer matrix to result in a range of opacities within the intraocular mask.

7. The ophthalmic device of claim 3, wherein the plurality of photochromic chromophores comprise spiropyran.

8. The ophthalmic device of claim 1, wherein the external stimulus is chosen from the group consisting of light, heat, and electrical current.

9. The ophthalmic device of claim 1, wherein the external stimulus comprises heat provided by a laser.

10. The ophthalmic device of claim 1, wherein the external stimulus comprises radiant energy focused through an axicon lens.

11. The ophthalmic device of claim 1, wherein the external stimulus is provided by light primarily in a wavelength chosen from the group of ultraviolet light, infrared light, and visible light.

12. The ophthalmic device of claim 1, wherein the mask is configured to switch between the first size, the second size, and a third size in response to an external stimulus.

13. The ophthalmic device of claim 1, wherein the aperture is surrounded by a first annular zone.

14. The ophthalmic device of claim 13, wherein the first annular zone is configured to switch between a first level of opacity and a second level of opacity in response to application of the external stimulus.

15. The ophthalmic device of claim 14, further comprising a second annular zone.

16. The ophthalmic device of claim 15, wherein the second annular zone is configured to block transmission of substantially all visible light.

17. The ophthalmic device of claim 15, wherein the second annular zone is configured to switch between a third level of opacity and a fourth level of opacity in response to application of the external stimulus.

18. The ophthalmic device of claim 17, wherein the first and second annular zones comprise a plurality of photochromic chromophores within a polymer matrix.

19. The ophthalmic device of claim 18, wherein the photochromic chromophores are distributed homogenously.

20. The ophthalmic device of claim 18, wherein the photochromic chromophores are distributed heterogeneously.

21. The ophthalmic device of claim 18, wherein the first annular zone comprises a first concentration of photochromic chromophores and the second annular zone comprises a second concentration of photochromic chromophores.

22. An intraocular mask, comprising:

an aperture configured to transmit substantially all visible light along the optical axis of the eye;

a first annular zone surrounding the aperture, the first annular zone configured to switch between a first level of opacity and a second level of opacity in response to application of an external stimulus;

wherein the first annular zone is configured to remain locked into the second level of opacity after removal of the external stimulus until another application of the external stimulus, the first annular zone then returning to the first level of opacity; and

a second annular zone surrounding the aperture, the second annular zone configured to block transmission of substantially all visible light.