Energy delivery systems and uses thereof

• US 10,357,312 B2
• Filed: 12/27/2017
• Issued: 07/23/2019
• Est. Priority Date: 07/28/2009
• Status: Active Grant

• Current Assignee: Neuwave Medical, Inc. (Johnson & Johnson)
• Original Assignee: Neuwave Medical, Inc. (Johnson & Johnson)
• Inventors: van der Weide, Daniel Warren, Laeseke, Paul F., Lee, Jr., Fred T., Brace, Christopher Lee
• Primary Examiner(s): Hulbert, Amanda K
• Assistant Examiner(s): Edwards, Philip C
• Application Number:
  US15/855,163
• Publication Number:
  US 20180132934A1
• Time in Patent Office: 573 Days
• CPC Class Codes: A61B 18/1815 using microwaves
• CPC Class Codes: A61B 2017/00084 Temperature
• CPC Class Codes: A61B 2017/00199 with a console, e.g. a control panel with a display
• CPC Class Codes: A61B 2018/00017 with gas
• CPC Class Codes: A61B 2018/00023 closed, i.e. without wound contact by the fluid
• CPC Class Codes: A61B 2018/00029 open
• CPC Class Codes: A61B 2018/00077 high, i.e. electrically conducting
• CPC Class Codes: A61B 2018/00172 Connectors and adapters therefor
• CPC Class Codes: A61B 2018/00178 Electrical connectors
• CPC Class Codes: A61B 2018/00279 deployable
• CPC Class Codes: A61B 2018/00351 Heart
• CPC Class Codes: A61B 2018/00488 Esophagus
• CPC Class Codes: A61B 2018/00577 Ablation
• CPC Class Codes: A61B 2018/00595 Cauterization
• CPC Class Codes: A61B 2018/00601 Cutting
• CPC Class Codes: A61B 2018/00642 with feedback, i.e. closed loop control
• CPC Class Codes: A61B 2018/00702 Power or energy
• CPC Class Codes: A61B 2018/00714 Temperature
• CPC Class Codes: A61B 2018/00791 Temperature
• CPC Class Codes: A61B 2018/00904 Automatic detection of target tissue
• CPC Class Codes: A61B 2018/00982 : combined with or comprising means for visual or photographic inspections inside the body, e.g. endoscopes
• CPC Class Codes: A61B 2018/1823 : Generators therefor
• CPC Class Codes: A61B 2018/1838 : Dipole antennas
• CPC Class Codes: A61B 2018/1869 : with an instrument interstitially inserted into the body, e.g. needles
• CPC Class Codes: A61B 2090/0807 : Indication means
• CPC Class Codes: A61B 2090/3762 : using computed tomography systems [CT]
• CPC Class Codes: A61B 2090/378 : using ultrasound
• CPC Class Codes: A61B 34/71 : Manipulators operated by drive cable mechanisms
• CPC Class Codes: A61B 90/92 : coded with colour
• CPC Class Codes: A61B 90/98 : using electromagnetic means, e.g. transponders

Abstract

The present invention relates to comprehensive systems, devices and methods for delivering energy to tissue for a wide variety of applications, including medical procedures (e.g., tissue ablation, resection, cautery, vascular thrombosis, treatment of cardiac arrhythmias and dysrhythmias, electrosurgery, tissue harvest, etc.). In certain embodiments, systems, devices, and methods are provided for treating a tissue region (e.g., a tumor) through application of energy.

Claims

1. A system, comprising

a microwave ablation device comprising

a proximal region, a central region and a distal region, the distal region comprising an antenna configured to deliver microwave ablation energy,

at least one stick region positioned within said central region and/or the proximal region and configured to attain and maintain a temperature causing freezing of tissue to facilitate adhering of the tissue to the stick region in order to stabilize the microwave ablation device in a desired position with respect to a tissue region during microwave ablation;

and

a processor comprising processor software configured for operating the microwave ablation device.

2. The system of claim 1, wherein the ablation device further comprises one or more coolant tubes or channels configured to deliver coolant to the stick region and/or the antenna.

3. The system of claim 1, wherein the antenna comprises a coaxial transmission line.

4. The system of claim 1, wherein the antenna comprises a tri-axial antenna transmission line.

5. The system of claim 1, wherein the distal region and central region are separated by a plug region.

6. The system of claim 5, wherein the plug region is configured to prevent cooling of the distal region resulting from cooling of the central region.

7. The system of claim 1, further comprising a seal positioned between the stick region and the distal region thereby preventing exposure of the stick region to the distal region.

8. The system of claim 7, further comprising software configured to interact with the processor, wherein the software is configured to provide a drawn desired ablation zone based upon inputted information associated with a tissue region.

9. The system of claim 8, wherein the inputted information is one or more of the following types of information:

type of the tissue region, location of the tissue region, location of vascular vessels associated with the tissue region, location of vulnerable structures associated with the tissue region, blood flow information associated with the tissue region.

10. The system of claim 8, wherein the software is configured to adjust the drawn desired ablation zone in real time during a procedure based upon additional inputted information, wherein the additional inputted information is one or more of changes in temperature of the microwave ablation device, changes in temperature of the tissue region, changes in size of the tissue region, and changes in vascularity associated with the tissue region.

11. The system of claim 8, wherein the processor is configured to operate the microwave ablation device such that the microwave ablation device ablates a tissue region consistent with the drawn desired ablation zone.

12. The system of claim 1, wherein the processor is configured to regulate the amount of microwave energy provided to a tissue region through the microwave ablation device.

13. The system of claim 12, wherein the regulation of the amount of microwave energy provided to a tissue region is accomplished through monitoring one or more of the following:

changes in temperature of the microwave ablation device, changes in temperature of the tissue region, changes in size of the tissue region, changes in shape of the tissue region, and changes in vascularity associated with the tissue region.

14. The system of claim 13, wherein the monitoring is in real time.

15. The system of claim 1, wherein the processor is configured to deliver coolant to the stick region for purposes of freezing the tissue to facilitate adhering of the tissue to the stick region.

16. The system of claim 2, wherein the processor is configured to circulate coolant through the one or more coolant tubes or channels.

17. The system of claim 1, wherein the processor is configured to circulate coolant to the central and/or distal region of the microwave ablation device upon user activation of the microwave ablation device.