Methods of using interleukin-10 for treating solid tumors
First Claim
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1. A method of treating a solid tumor in a human subject, comprising:
- administering to the human subject a therapeutically effective amount of a PEG-IL-10 agent;
wherein the PEG-IL-10 agent is mature human PEG-IL-10, is recombinantly made in bacteria, and is a mixture of mono-pegylated and di-pegylated IL-10,wherein the amount of the PEG-IL-10 agent administered is 5-20 μ
g/kg,and wherein the PEG-IL-10 agent is dosed daily.
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Abstract
Methods of treating subjects having a disease or disorder responsive to IL-10, including methods of administration and dosing regimens associated therewith, are provided.
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12 Claims
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1. A method of treating a solid tumor in a human subject, comprising:
- administering to the human subject a therapeutically effective amount of a PEG-IL-10 agent;
wherein the PEG-IL-10 agent is mature human PEG-IL-10, is recombinantly made in bacteria, and is a mixture of mono-pegylated and di-pegylated IL-10, wherein the amount of the PEG-IL-10 agent administered is 5-20 μ
g/kg,and wherein the PEG-IL-10 agent is dosed daily. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
- administering to the human subject a therapeutically effective amount of a PEG-IL-10 agent;
Specification