Injection device with an end of dose feedback mechanism

• US 10,357,616 B2
• Filed: 11/17/2017
• Issued: 07/23/2019
• Est. Priority Date: 01/25/2005
• Status: Active Grant

• Current Assignee: Novo Nordisk A/S
• Original Assignee: Novo Nordisk A/S
• Inventors: Moller, Claus Schmidt, Radmer, Bo, Nielsen, Lars Ulrik, Enggaard, Christian Peter
• Primary Examiner(s): Farrar, Lauren P
• Application Number:
  US15/815,976
• Publication Number:
  US 20180071459A1
• Time in Patent Office: 613 Days
• CPC Class Codes: A61M 2205/581 by audible feedback
• CPC Class Codes: A61M 2205/582 by tactile feedback
• CPC Class Codes: A61M 5/20 Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically A61M5/142 , A61M5/46 take precedence; hypodermic projectiles F42B12/54
• CPC Class Codes: A61M 5/24 Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic ampoules or carpules A61J1/06
• CPC Class Codes: A61M 5/31535 Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
• CPC Class Codes: A61M 5/3155 by rotational movement of dose setting member, e.g. during setting or filling of a syringe
• CPC Class Codes: A61M 5/31551 including axial movement of dose setting member
• CPC Class Codes: A61M 5/31561 using freely adjustable volume steps
• CPC Class Codes: A61M 5/3157 Means providing feedback signals when administration is completed A61M5/20 takes precedence
• CPC Class Codes: A61M 5/31585 performed by axially moving actuator, e.g. an injection button

Abstract

An injection device with a dose delivering mechanism being adapted to provide a non-visual, e.g. audible and/or tactile, feedback signal when a set dose has been at least substantially injected. A first and a second part of the injection device are adapted to perform a relative rotational movement with respect to each other. The relative rotational movement causes at least two parts of the injection device to abut or engage, and this abutment or engagement causes the non-visual feedback signal to be generated. A very distinct and precise feedback is provided as compared to prior art axial solutions because the generation of the feedback signal is initiated by the relative rotational movement.

Feedback signal may be generated by a change in a rotational velocity of at least one part, e.g. by changing the pitch of a threaded portion or by engaging a non-rotating part and a rotating part, thereby causing the non-rotating part to start rotating. May alternatively be generated by building up and releasing a tension.

The injection device is suitable for injecting insulin.

Claims

1. An injection device comprising:

a housing having a longitudinal axis,

a dose setting member being operable by a user to set a desired dose of a varying amount to be injected, the desired dose thereby being a set dose,

a piston rod being adapted to cooperate with a piston so as to cause a set dose to be injected from an ampoule, and

a dose delivering mechanism being adapted to operate the piston rod in such a way that the set dose is injected by a mechanically biased mechanism comprising at least one spring and wherein the injection is subsequently performed by releasing the stored energy previously built up in the mechanically biased mechanism and which stored energy will cause the set dose to be injected, the dose delivering mechanism further being adapted to provide an audible feedback signal to a user only at the end of injection of the set dose,

wherein first and second parts of the injection device are adapted to perform a relative rotational movement around a longitudinal axis with respect to each other during injection of the set dose, and wherein said relative rotational movement causes at least the first part and the second part of the injection device to abut or engage, said abutment or engagement causing the audible feedback signal to be generated,

wherein the audible feedback signal is generated as the first part and the second part of the dose delivering mechanism performing said relative rotational movement are moved against each other, and

the audible feedback signal is generated by releasing a tension which has previously been introduced in a part of the injection device comprising at least one resilient portion of at least one of the first part and the second part performing said relative rotational movement.

2. The injection device according to claim 1, wherein the abutment or engagement is caused by a change in a rotational velocity of at least one part of the dose delivering mechanism.

3. The injection device according to claim 2, further comprising a ratchet operating the piston rod and having a threaded portion being adapted to engage with a part of the dose delivering mechanism, and wherein the change in a rotational velocity is generated by a change in the pitch of the threaded portion of the ratchet, said change in the pitch in return causing a change in a translational velocity of said part of the dose delivering mechanism, said change in translational velocity causing at least two parts of the injection device to abut, thereby causing the audible feedback signal to be generated.

4. The injection device according to claim 2, wherein the dose delivering mechanism comprises a first dose part and a second dose part, the first dose part being adapted to rotate relatively to the housing during injection of a dose and the first dose part comprising structure for engaging the second dose part at the end of injection of a set dose, thereby causing the second dose part to rotate along with the first dose part, and wherein the audible feedback signal is generated by the resulting rotational movement of the second dose part.

5. The injection device according to claim 4, wherein the second dose part is positioned between the first dose part and the housing.

6. The injection device according to claim 1, wherein the at least one resilient portion is a spring arm.

7. The injection device according to claim 6, wherein the tension is introduced during dose setting.

8. The injection device according to claim 1, wherein the tension is introduced during dose setting.

9. The injection device according to claim 1, wherein the tension is introduced during injection of a dose.