System and method for using impedance to determine proximity and orientation of segmented electrodes

• US 10,357,652 B2
• Filed: 05/31/2018
• Issued: 07/23/2019
• Est. Priority Date: 06/28/2011
• Status: Active Grant

• Current Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Inventors: Bradley, Kerry
• Primary Examiner(s): Koharski, Christopher
• Assistant Examiner(s): Dinga, Roland
• Application Number:
  US15/993,897
• Publication Number:
  US 20180272127A1
• Time in Patent Office: 418 Days
• CPC Class Codes: A61B 5/0538 invasively, e.g. using a catheter
• CPC Class Codes: A61B 5/06 Devices, other than using radiation, for detecting or locating foreign bodies for removing same A61B17/50 ; determining position of probes within or on the body of the patient
• CPC Class Codes: A61B 5/068 using impedance sensors
• CPC Class Codes: A61N 1/0551 Spinal or peripheral nerve electrodes
• CPC Class Codes: A61N 1/36125 Details of circuitry or electric components
• CPC Class Codes: A61N 1/36182 Direction of the electrical field, e.g. with sleeve around stimulating electrode
• CPC Class Codes: A61N 1/37217 characterised by the communication link, e.g. acoustic or tactile
• CPC Class Codes: A61N 1/37241 providing test stimulations
• CPC Class Codes: A61N 1/3787 from an external energy source

Abstract

A method for implanting a neurostimulation lead within a patient includes measuring impedances of electrodes on the lead in order to correctly position the lead relative to a target tissue region. The electrodes are circumferentially segmented electrodes that are spaced from each other about the longitudinal axis of the lead. When the difference between the impedances of the electrodes exceeds a threshold value, the lead is in the correct position. In accordance with another embodiment, impedance measurements are used to select which one of the electrodes is closest to the target tissue region. By determining which electrode has the highest impedance and which electrode has the lowest impedance, the type of tissue adjacent to each electrode can be determined based on the conductivity properties of the tissue. The target tissue region may be a spinal cord, a posterior longitudinal ligament, white matter, or gray matter.

Claims

1. A method performed using a neurostimulation lead positioned within the patient proximate to a tissue volume having conductive properties, wherein the tissue volume includes a target tissue region having distinguishable conductive properties from a remainder of the tissue volume, and the neurostimulation lead has a longitudinal axis and an electrode ring segmented into at least two electrodes circumferentially spaced from each other about the longitudinal axis, the method comprising:

determining at least one value for each of the at least two electrodes based on the conductive properties of the tissue volume; and

based on the at least one determined value, identifying information related to electrode position with respect to the target tissue region for use in providing a therapy to the patient.

2. The method of claim 1, wherein the identifying information related to electrode position with respect to the target volume includes identifying at least one of the at least two electrodes positioned closest to the target tissue region.

3. The method of claim 1, wherein the identifying information related to electrode position with respect to the target volume includes identifying information for rotating the neurostimulation lead to position at least one of the at least two electrodes closer to the target tissue region.

4. The method of claim 1, wherein the determining at least one value for each of the at least two electrodes based on the conductive properties of the tissue volume includes measuring an impedance.

5. The method of claim 1, wherein the determining at least one value for each of the at least two electrodes based on the conductive properties of the tissue volume includes measuring a field potential.

6. The method of claim 1, wherein the target tissue region comprises at least one of a spinal cord, a posterior longitudinal ligament, a white matter, or a gray matter.

7. The method of claim 1, wherein the neural stimulation lead is positioned proximate to a spinal cord, and the target tissue region comprises the spinal cord.

8. The method of claim 1, wherein the neural stimulation lead is positioned in a brain, and the target tissue region comprises gray matter or white matter.

9. A non-transitory machine-readable medium including instructions, which when executed by a machine, cause the machine to perform a process using a neurostimulation lead positioned within the patient proximate to a tissue volume having conductive properties, wherein the tissue volume includes a target tissue region having distinguishable conductive properties from a remainder of the tissue volume, and the neurostimulation lead has a longitudinal axis and an electrode ring segmented into at least two electrodes circumferentially spaced from each other about the longitudinal axis, and wherein the instructions, which when executed by the machine, cause the machine to:

determine at least one value for each of the at east two electrodes based on the conductive properties of the tissue volume; and

based on the at least one determined value, identify information related to electrode position with respect to the target tissue region for use in providing a therapy to the patient.

10. The non-transitory machine-readable medium of claim 9, wherein the information related to electrode position with respect to the target volume includes information regarding at least one of the at least two electrodes positioned closest to the target tissue region.

11. The non-transitory machine-readable medium of claim 9, wherein the information related to electrode position with respect to the target volume includes information for rotating the neurostimulation lead to position at least one of the at least two electrodes closer to the target tissue region.

12. The non-transitory machine-readable medium of claim 9, wherein the at least one value includes at least one impedance value.

13. The non-transitory machine-readable medium of claim 9, wherein the at least one value includes at least one field potential value.

14. The non-transitory machine-readable medium of claim 9, wherein the target tissue region comprises at least one of a spinal cord, a posterior longitudinal ligament, a white matter, or a gray matter.

15. A system for use with a neurostimulation lead positioned within a patient proximate to a tissue volume that includes a target tissue region having conductive, wherein the tissue volume includes a target tissue region having distinguishable conductive properties from a remainder of the tissue volume, and the neurostimulation lead has a longitudinal axis and an electrode ring segmented into at least two electrodes circumferentially spaced from each other about the longitudinal axis, the system comprising:

circuitry configured to determine at least one value for each of the at least two electrodes based on the conductive properties of the tissue volume; and

a processor configured to, based on the at least one determined value, identify information related to electrode position with respect to the target tissue region for use in providing a therapy to the patient.

16. The system of claim 15, wherein the information related to electrode position with respect to the target volume includes information regarding at least one of the at least two electrodes positioned closest to the target tissue region.

17. The system of claim 15, wherein the information related to electrode position with respect to the target volume includes information for rotating the neurostimulation lead to position at least one of the at least two electrodes closer to the target tissue region.

18. The system of claim 15, wherein the at least one value includes at least one impedance value.

19. The system of claim 15, wherein the at least one value includes at least one field potential value.

20. The system of claim 15, wherein the target tissue region comprises at least one of a spinal cord, a posterior longitudinal ligament, a white matter, or a gray matter.