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Foamable vehicles and pharmaceutical compositions comprising aprotic polar solvents and uses thereof

  • US 10,363,216 B2
  • Filed: 12/31/2018
  • Issued: 07/30/2019
  • Est. Priority Date: 04/28/2009
  • Status: Active Grant
First Claim
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1. A method of treating a skin, mucosal, or body cavity disorder comprising administering to skin, mucosal, or body cavity a composition comprising:

  • a) about 1% to about 5% of a minocycline;

    b) one or more short chain alcohols comprising ethanol;

    c) about 2% to about 50% by weight of the composition of one or more protic polar solvents comprising propylene glycol;

    d) one or more polymeric agents comprising a cellulose ether;

    e) one or more modulating agents comprising an antioxidizing agent;

    f) a metal; and

    g) an essential oil;

    wherein the composition is essentially free of fatty alcohol;

    wherein the composition is surfactant free; and

    wherein the composition is waterless.

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