Intraocular shunt implantation

• US 10,369,048 B2
• Filed: 09/13/2017
• Issued: 08/06/2019
• Est. Priority Date: 06/28/2013
• Status: Active Grant

• Current Assignee: AqueSys, Inc. (Abbvie Incorporated)
• Original Assignee: AqueSys, Inc. (Abbvie Incorporated)
• Inventors: Horvath, Christopher, Romoda, Laszlo O., Lewis, Richard A.
• Primary Examiner(s): Klein, Benjamin J
• Application Number:
  US15/703,802
• Publication Number:
  US 20180008464A1
• Time in Patent Office: 692 Days
• CPC Class Codes: A61F 9/00781 Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment drainage implants in general A61M27/002

Abstract

Implanting an intraocular shunt into an eye can involve creating an opening in the cornea and positioning a shunt in the anterior chamber of the eye such that the shunt terminates between layers of Tenon'"'"'s capsule, thereby facilitating fluid flow out of the anterior chamber into a space between the layers of Tenon'"'"'s capsule.

Claims

1. A method of treating glaucoma comprising inserting an intraocular shunt into eye tissue such that an inflow end of the shunt is positioned in the anterior chamber of the eye and an outflow end of the shunt is positioned between layers of Tenon'"'"'s capsule.

2. The method of claim 1, wherein the inserting further comprises introducing the shunt into the eye through the cornea.

3. The method of claim 1, wherein a device for deploying the intraocular shunt comprises a shaft configured to hold the shunt, and wherein the inserting comprises advancing the shaft into sclera until reaching and no further than a first position at which a bevel of the shaft is positioned between the layers of Tenon'"'"'s capsule.

4. The method of claim 3, wherein after reaching the first position, the inserting comprises advancing a pusher component of the device such that the shunt is pushed distally out of the shaft.

5. The method of claim 4, wherein the advancing the pusher component comprises pushing less than an entire length of the shunt distally out of the shaft.

6. The method of claim 4, wherein the device comprises a sleeve having a distal end and a lumen, the shaft being disposed within the lumen, wherein the inserting further comprises advancing the pusher component to a distal most position at which a distal end of the pusher component is positioned longitudinally proximal to the sleeve distal end.

7. The method of claim 4, wherein the device comprises a sleeve having a distal end and a lumen, the shaft being disposed within the lumen, and wherein at the first position, the sleeve distal end is spaced apart from the eye tissue.

8. The method of claim 7, wherein the inserting further comprises advancing the pusher component until a distal end of the pusher component is positioned longitudinally adjacent to the sleeve distal end.

9. The method of claim 7, wherein the sleeve distal end is spaced apart from anterior chamber angle tissue in the first position.

10. The method of claim 7, wherein the inserting further comprises, while maintaining the shaft substantially fixed relative to the sclera, advancing the sleeve distally over the shaft until the sleeve distal end contacts eye tissue.

11. The method of claim 10, wherein after the sleeve distal end contacts the eye tissue, the inserting further comprises proximally withdrawing the shaft from the sclera until the bevel is received within a lumen of the sleeve.

12. A method of treating glaucoma comprising inserting an intraocular shunt into eye tissue such that the shunt conducts fluid from the anterior chamber of the eye to a region between layers of Tenon'"'"'s capsule.

13. The method of claim 12, further comprising inserting a hollow shaft into the eye, the shaft configured to hold the shunt.

14. The method of claim 13, wherein the inserting comprises entering the eye through the cornea.

15. The method of claim 12, wherein an intra-Tenon'"'"'s adhesion space defined between the layers of Tenon'"'"'s capsule comprises a deep layer and a superficial layer, and the inserting comprises positioning an outflow end of the shunt between the deep and superficial layers.

16. The method of claim 15, further comprising advancing a bevel of a shaft to a position between the deep and superficial layers, and the advancing comprises distally advancing the shunt from the shaft into the intra-Tenon'"'"'s adhesion space while maintaining the bevel stationary relative to the eye tissue.

17. The method of claim 12, wherein a device for deploying the intraocular shunt comprises a shaft configured to hold the shunt, and wherein the inserting comprises advancing the shaft into sclera until reaching and no further than a first position at which a bevel of the shaft is positioned between the layers of Tenon'"'"'s capsule.

18. The method of claim 17, wherein after reaching the first position, the inserting comprises advancing a pusher component of the device such that the shunt is pushed distally out of the shaft.

19. The method of claim 18, wherein the advancing the pusher component comprises pushing less than an entire length of the shunt distally out of the shaft.

20. The method of claim 18, wherein the device comprises a sleeve having a distal end and a lumen, the shaft being disposed within the lumen, wherein the inserting further comprises advancing the pusher component to a distal most position at which a distal end of the pusher component is positioned longitudinally proximal to the sleeve distal end.