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Nonracemic mixtures and uses thereof

  • US 10,369,134 B2
  • Filed: 12/04/2018
  • Issued: 08/06/2019
  • Est. Priority Date: 12/05/2017
  • Status: Active Grant
First Claim
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1. A method of alleviating bipolar disorder comprising administering to a subject in need thereof an effective amount of a composition comprising:

  • an amount about 85 mg to about 600 mg of (R)-(+)-amisulpride, or a pharmaceutically acceptable salt thereof, by weight of free base; and

    an amount about 15 mg to about 100 mg (S)-(−

    )-amisulpride, or a pharmaceutically acceptable salt thereof, by weight of free base;

    wherein the enantiomeric ratio of (R)-(+)-amisulpride to (S)-(−

    )-amisulpride in the composition is about 65;

    35 to about 88;

    12 by weight of free base.

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