Neural prosthetic with touch-like sensing

• US 10,369,362 B2
• Filed: 01/24/2013
• Issued: 08/06/2019
• Est. Priority Date: 06/28/2004
• Status: Active Grant

• Current Assignee: Alfred E. Mann Foundation For Scientific Research
• Original Assignee: Alfred E. Mann Foundation For Scientific Research
• Inventors: Karr, Lawrence J., Schulman, Joseph H.
• Primary Examiner(s): Hindenburg, Max F
• Application Number:
  US13/749,468
• Publication Number:
  US 20140207252A1
• Time in Patent Office: 2,385 Days
• Field of Search: 607 49, 128897
• CPC Class Codes: A61B 5/053 Measuring electrical impedance or conductance of a portion of the body
• CPC Class Codes: A61N 1/3605 Implantable neurostimulators for stimulating central or peripheral nerve system

Abstract

An apparatus and method is related to providing sensing functions that are similar to “human touch” when located in a prosthetic device such as a BION microstimulator that is implanted in a patient. The apparatus includes a power circuit, a communication circuit and a sensor circuit. The power circuit provides power to the communication circuit and the sensor circuit. The sensor cooperates with the communication circuit, which communicates to the brain. The sensor uses various techniques to detect changes in the environment for the surrounding tissue using criteria such as reflectivity, impedance, conductivity, return signal spectrum, return signal rate and return signal phase to name a few. For example, the impedance observed by the sensor changes when: the skin tissue is deformed around the sensor, or when the skin is surrounded by water. The sensory information is interpreted by the brain as an analog of touch or feel.

Claims

1. An implantable neural prosthetic sensor device that is configured to be implanted in tissue, comprising:

a tuned circuit that has a resonant frequency that varies as influenced by an environmental condition associated with the tissue, wherein the tuned circuit comprises a radio frequency (RF) sensor, the RF sensor being configured to perceive the tissue as a complex impedance, the resonant frequency of the tuned circuit being responsive to the complex impedance perceived by the RF sensor, and wherein the complex impedance perceived by the RF sensor is responsive to the environmental condition associated with the tissue; and

a signal processor that is configured to evaluate the complex impedance perceived by the RF sensor to provide thereby sensory information for a neural prosthetic based on the tuned circuit resonant frequency.

2. The implantable neural prosthetic sensor device of claim 1, wherein the environmental condition comprises at least one of:

ambient temperature of the tissue, surface temperature of a surface of the tissue, pressure exerted on the surface by a foreign object, heat exerted on the surface by the foreign object, cold exerted on the surface by the foreign object, and deformation of a region of tissue about the prosthetic sensor device.

3. The implantable neural prosthetic sensor device of claim 1, further comprising:

a fixed frequency oscillator that is arranged to generate a first signal having a first frequency;

a voltage controlled oscillator comprising a voltage controlled circuit and the tuned circuit, said voltage controlled circuit coupled to the tuned circuit, said voltage controlled oscillator being responsive to a control signal, wherein the voltage controlled oscillator is arranged to generate a second signal having a second frequency in response to the control signal, wherein the second frequency of the voltage controlled oscillator varies in response to environmental conditions associated with the tissue; and

a signal comparator arranged to compare the first frequency to the second frequency to provide thereby the control signal such that the second frequency is substantially matched to the first frequency.

9. The implantable neural prosthetic sensor device of claim 1 wherein the tuned circuit comprises an inductor, a capacitor, and the RF sensor.

10. The implantable neural prosthetic sensor device of claim 1 wherein:

the RF sensor is an antenna;

the antenna perceives the tissue as the complex impedance;

the resonant frequency of the tuned circuit is responsive to the complex impedance perceived by the antenna; and

the complex impedance perceived by the antenna is responsive to the environmental conditions associated with the tissue.

4. An implantable neural prosthetic sensor device that is configured to be implanted in tissue, comprising:

a fixed frequency oscillator that is arranged to generate a first signal having a first frequency;

a variable frequency oscillator that includes a tuned circuit, said variable frequency oscillator being responsive to a closed loop control signal, wherein the variable frequency oscillator is arranged to generate a second signal having a second frequency, wherein the resonant frequency of the tuned circuit is responsive to environmental conditions associated with the tissue, the tuned circuit comprises a radio frequency (RF) sensor, the RF sensor being configured to perceive the tissue as a complex impedance, the resonant frequency of the tuned circuit being responsive to the complex impedance perceived by the RF sensor, and wherein the complex impedance perceived by the RF sensor is responsive to the environmental conditions associated with the tissue;

a signal comparator that is arranged to compare the first frequency to the second frequency to provide thereby the closed loop control signal; and

a signal processor configured to evaluate the complex impedance perceived by the RF sensor to provide thereby sensory information for a neural prosthetic associated with the environmental conditions associated with the tissue based on the closed loop control signal.

5. The implantable neural prosthetic sensor device of claim 4, wherein the tuned circuit comprises an inductor-capacitor (LC) tank circuit, wherein at least one of a capacitance and an inductance associated with the LC tank circuit is altered in response to the environmental conditions associated with the tissue.

11. The implantable neural prosthetic sensor device of claim 4 wherein the signal comparator provides the closed loop control signal such that the second frequency matches the first frequency.

12. The implantable neural prosthetic sensor device of claim 4 wherein the tuned circuit comprises an inductor, a capacitor, and the RF sensor.

13. The implantable neural prosthetic sensor device of claim 4 wherein:

the RF sensor is an antenna;

the antenna perceives the tissue as the complex impedance;

the resonant frequency of the tuned circuit is responsive to the complex impedance perceived by the antenna; and

the complex impedance perceived by the antenna is responsive to the environmental conditions associated with the tissue.

6. An implantable neural prosthetic sensor device that is configured to be implanted into tissue, comprising:

a fixed frequency oscillator that is arranged to generate a first signal having a first frequency, a first amplitude, and a first phase;

a tuned circuit that is coupled to the fixed frequency oscillator and arranged to receive the first signal, wherein the tuned circuit is arranged to provide a second signal having a second frequency, a second amplitude, and a second phase, wherein at least one of the second frequency, the second amplitude, and the second phase is altered as influenced by the tissue environment; and

a signal processor circuit that is arranged to compare the first signal to the second signal to provide sensory information that is associated with the environmental conditions associated with the tissue,

wherein the tuned circuit comprises a radio frequency (RF) sensor, the RF sensor being configured to perceive the tissue as a complex impedance;

wherein at least one of the second frequency, the second amplitude, and the second phase is responsive to the complex impedance perceived by the RF sensor;

wherein the complex impedance perceived by the RF sensor is responsive to the tissue environment; and

wherein the signal processor circuit is configured to evaluate the complex impedance perceived by the RF sensor to provide sensory information for a neural prosthetic based on the complex impedance perceived by the RF sensor.

7. The implantable neural prosthetic sensor device of claim 6, wherein the signal processor circuit comprises at least one of:

an amplitude detector, a phase detector, a frequency detector, an amplitude comparator, a phase comparator, and a frequency comparator.

8. The implantable neural prosthetic sensor device of claim 6, further comprising at least one of:

a communication circuit that is arranged to communicate the sensory information to a master control unit, a capture circuit that is arranged to store the sensory information, and an encoder that is arranged to encode the sensory information in a data signal.

14. The implantable neural prosthetic sensor device of claim 6 wherein the tissue environment is the presence of an object in proximity to the tissue.

15. The implantable neural prosthetic sensor device of claim 14 wherein the sensory information is a property of the object.

16. The implantable neural prosthetic sensor device of claim 14 wherein the sensory information is the presence of a particular material in the object.

17. The implantable neural prosthetic sensor device of claim 6 wherein the tuned circuit comprises an inductor, a capacitor, and RF sensor.

18. The implantable neural prosthetic sensor device of claim 6 wherein:

the RF sensor is an antenna;

the antenna perceives the tissue as the complex impedance;

at least one of the second frequency, the second amplitude, and the second phase is responsive to the complex impedance perceived by the antenna; and

the complex impedance perceived by the antenna is responsive to the tissue environment.