Apparatus and method for vessel occlusion removal

• US 10,376,274 B2
• Filed: 07/14/2016
• Issued: 08/13/2019
• Est. Priority Date: 07/16/2015
• Status: Active Grant

• Current Assignee: Perflow Medical Ltd.
• Original Assignee: Perflow Medical Ltd.
• Inventors: Farin, Danny, Cibulski, Gilad, Rapaport, Avraham, Bonneau, Itamar
• Primary Examiner(s): Yabut, Diane D
• Assistant Examiner(s): Jamialahmadi, Majid
• Application Number:
  US15/568,826
• Publication Number:
  US 20180103970A1
• Time in Patent Office: 1,125 Days
• Field of Search: 606200, 606127, 606159
• CPC Class Codes: A61B 17/12109 in a blood vessel
• CPC Class Codes: A61B 17/221 Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions surgical snare instruments A61B17/32056
• CPC Class Codes: A61B 17/320725 with radially expandable cutting or abrading elements A61B17/32075 takes precedence
• CPC Class Codes: A61B 2017/22034 for gripping the obstruction or the tissue part from inside
• CPC Class Codes: A61B 2017/2212 having a closed distal end, e.g. a loop
• CPC Class Codes: A61B 2017/320064 with tissue or sample retaining means

Abstract

According to an aspect of some embodiments of the present invention there is provided a device for removal of obstructive material from a vessel comprising:

• • an expandable structure sized for insertion into the vessel; and
  • one or more portion protruding radially from a central longitudinal axis of the expandable structure such that a space between the protrusion and a closest portion of the expandable structure to the portion includes a radial component;
  • wherein the space is sized and shaped to be suitable to accept obstructive material.

Claims

1. A device for removal of obstructive material from a vessel comprising:

an expandable structure sized for insertion into the vessel; and

one or more protrusion extending radially from a central longitudinal axis of said expandable structure such that a space is generated between said one or more protrusion and a closest portion of said expandable structure;

wherein said space is sized and shaped to be suitable to accept obstructive material; and

wherein said expandable structure includes a woven structure having warp and weft wires, said one or more protrusion is in the form of a wire with two ends, one end of said two ends forming said weft or warp wire of said woven structure and a second end of said two ends, opposite to said one end, forming a continuation of said weft or warp wire of said woven structure.

2. The device according to claim 1, wherein said device includes wires, wherein said one or more protrusion is a portion of a wire.

3. The device according to claim 1, wherein said space between said one or more protrusion and said closest portion of said expandable structure is enlarged by a separation between one or more portion of the device increasing at least in one dimension.

4. The device according to claim 3, wherein said separation comprises a radial component.

5. The device according to claim 3, wherein said separation comprises a component tangential to said central longitudinal axis of said device.

6. The device according to claim 3, wherein said separation comprises a component parallel to said central longitudinal axis of said device.

7. The device according to claim 1, wherein said space between said one or more protrusion and said closest portion of said expandable structure is reduced by a separation between one or more portion of the device decreasing at least in one dimension.

8. The device according to claim 1, wherein said one or more protrusion is rounded.

9. The device according to claim 1, wherein a radial component of said space is between 0.01-0.2 mm.

10. The device according to claim 1, wherein said central longitudinal axis of said expandable structure is a central longitudinal axis of a largest cylindrical space enclosable within said expandable structure.

11. The device according to claim 10, wherein said largest cylindrical space is a largest length cylindrical space enclosable within said expandable structure.

12. The device according to claim 10, wherein said largest cylindrical space is a largest diameter cylindrical space enclosable within said expandable structure.

13. The device according to claim 10, wherein said largest cylindrical space is a largest volume cylindrical space enclosable within said expandable structure.

14. The device according to claim 10,

wherein said expandable structure is configured to have a collapsed state and a range of expanded shapes, wherein said expandable structure is expandable to a maximally expanded state,

wherein a diameter of said largest cylindrical space in said collapsed state is smaller than a volume of said largest cylindrical space in said maximally expanded state.

15. The device according to claim 14, wherein said diameter of said largest cylindrical space in said collapsed space is 0.3-2 mm.

16. The device according to claim 15, wherein said diameter of said largest cylindrical space in said maximally expanded state is 1-7 mm.

17. The device according to claim 16, wherein a radial component of said space is larger when said expandable structure is in each of said range of expanded shapes than a radial component of said space when said device is in said collapsed state.

18. The device according to claim 1,

wherein said one or more protrusion and said closest device portion are coupled at, at least two junctions, where an axial length of said one or more protrusion between said two junctions is longer than an axial length of said closest portion between said two junctions.

19. The device according to claim 1, wherein said

one or more protrusion and said closest portion are curved spatially arranged to have a phase difference between said one or more protrusion and said closest portion.

20. The device according to claim 1, wherein said one or more protrusion includes a plurality of protrusions.

21. The device according to claim 20, wherein said plurality of protrusions are disposed at different radial positions around an axial location along said expandable structure.

22. The device according to claim 20, wherein one or more of said plurality of protrusions is dispersed at a different axial location along said expandable structure from one or more other of said plurality of protrusions.

23. The device according to claim 1,

wherein said expandable structure comprises:

said warp and weft wires are each coupled at a different radial position at a distal and a proximal end of said expandable structure,

wherein each said warp and weft wires transverses a path from said distal end to said proximal end including changes in radial position,

wherein, during said path, one or more of said warp and weft wires passes over one or more other of said warp and weft wires and under one or more other of said warp and weft wires,

wherein said warp and weft wires forms a tubular shaped mesh surface between said distal and proximal ends;

wherein at least one portion of one of said warp and weft wires includes said protrusion where said path departs protrudes radially away from said tubular shaped mesh surface and then extends axially, defining said space between said at least one portion of one of said warp and weft wiresand said tubular shaped mesh surface.

24. The device according to claim 23, wherein said path including changes in radial position is a helical path.

25. The device according to claim 1, comprising

said warp and weft wires are each coupled at a different radial position at a distal and a proximal end of said expandable structure;

and

wherein each said warp and weft wires transverses a path from said distal end to said proximal end including changes in radial position;

wherein, during said path, one or more of said warp and weft wires passes over one or more other of said warp and weft wires and under one or more other wire;

wherein said warp and weft wires forms a tubular shaped mesh surface between said distal and proximal ends;

wherein at least one of said warp and weft wires includes said protruding portion.

26. The device according to claim 1 wherein said space is sized and shaped to be suitable to accept at least a portion of the obstructive material.

27. The device according to claim 1, wherein said one or more protrusion and said closest portion are attached to each other at two points located along said central longitudinal axis of said expandable structure, and wherein changing a distance between said two attachment points changes a size of said space.

28. The device according to claim 1, wherein said expandable structure is tubular and wherein said wire forming said one or more protrusion follows a path which departs from and returns to a surface of said expandable structure, extending radially away from said surface and axially along said central longitudinal axis of said expandable structure.

29. The device according to claim 1, wherein relative movement of said one or more protrusion and said closest portion pinches the obstructive material within said space.

30. The device of claim 1, wherein at least one of said warp and weft wires of said woven structure includes a curved section bridging sections of said wire and acting as said one or more protrusion.

31. The device of claim 1, wherein said one or more protrusion of said woven structure is formed by a curvature in said weft or warp wire.