Techniques for percutaneous mitral valve replacement and sealing
First Claim
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1. Apparatus, for use with a native valve of a heart of a subject, the native valve defining an area, the apparatus comprising:
- an annular upstream support portion, comprising an expandable first frame, the upstream support portion configured to be placed against an upstream surface of the native valve;
a flexible polyester connector;
an anchoring element, flexibly coupled to the upstream support portion by the connector, and configured to anchor the upstream support portion to the native valve by engaging tissue of the native valve; and
a prosthetic valve,wherein;
the upstream support portion is configured to support the prosthetic valve at the native valve, andthe prosthetic valve;
comprises (i) an expandable second frame that defines a lumen therethrough, and (ii) a plurality of prosthetic leaflets disposed within the lumen and coupled to the second frame,is configured to be positioned inward from the upstream support portion, andhas a cross-sectional area that is less than 90 percent of the area defined by the native valve.
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Abstract
Apparatus is provided for use with a native valve of a heart of a subject. The apparatus includes: (1) an annular upstream support portion, comprising an expandable first frame, the upstream support portion configured to be placed against an upstream surface of the native valve; (2) a flexible polyester connector; and (3) an anchoring element, flexibly coupled to the upstream support portion by the connector, and configured to anchor the upstream support portion to the native valve by engaging tissue of the native valve.
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Citations
31 Claims
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1. Apparatus, for use with a native valve of a heart of a subject, the native valve defining an area, the apparatus comprising:
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an annular upstream support portion, comprising an expandable first frame, the upstream support portion configured to be placed against an upstream surface of the native valve; a flexible polyester connector; an anchoring element, flexibly coupled to the upstream support portion by the connector, and configured to anchor the upstream support portion to the native valve by engaging tissue of the native valve; and a prosthetic valve, wherein; the upstream support portion is configured to support the prosthetic valve at the native valve, and the prosthetic valve; comprises (i) an expandable second frame that defines a lumen therethrough, and (ii) a plurality of prosthetic leaflets disposed within the lumen and coupled to the second frame, is configured to be positioned inward from the upstream support portion, and has a cross-sectional area that is less than 90 percent of the area defined by the native valve. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22)
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23. Apparatus, for use with a native valve of a heart of a subject, the apparatus comprising:
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an annular upstream support portion, comprising an expandable first frame, the upstream support portion configured to be placed against an upstream surface of the native valve; a flexible polyester connector; an anchoring element, flexibly coupled to the upstream support portion by the connector, and configured to anchor the upstream support portion to the native valve by engaging tissue of the native valve; and a prosthetic valve, wherein; the upstream support portion is configured to support the prosthetic valve at the native valve, the prosthetic valve; comprises (i) an expandable second frame that defines a lumen therethrough, and (ii) a plurality of prosthetic leaflets disposed within the lumen and coupled to the second frame, and is configured to be positioned inward from the upstream support portion, the connector comprises a covering, and the covering at least partly covers the first frame and the second frame, and is configured to facilitate coupling between the upstream support portion and the prosthetic valve. - View Dependent Claims (24, 25, 26, 27)
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28. Apparatus, for use with a native valve of a heart of a subject, the apparatus comprising:
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an annular upstream support portion, comprising an expandable first frame, the upstream support portion configured to be placed against an upstream surface of the native valve; a flexible polyester connector; an anchoring element, flexibly coupled to the upstream support portion by the connector, and configured to anchor the upstream support portion to the native valve by engaging tissue of the native valve; and a prosthetic valve, wherein; the upstream support portion is configured to support the prosthetic valve at the native valve, the prosthetic valve; comprises (i) an expandable second frame that defines a lumen therethrough, and (ii) a plurality of prosthetic leaflets disposed within the lumen and coupled to the second frame, and is configured to be positioned inward from the upstream support portion, and a height of the prosthetic valve is at least 3 times greater than a height of the upstream support portion. - View Dependent Claims (29, 30, 31)
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Specification