Light generating guide wire for intravascular use

• US 10,376,711 B2
• Filed: 08/06/2007
• Issued: 08/13/2019
• Est. Priority Date: 03/14/2003
• Status: Expired due to Fees

• Current Assignee: Light Sciences Oncology, Inc.
• Original Assignee: Light Sciences Oncology, Inc.
• Inventors: Burwell, Phillip, Guo, Zihong, Matson, Jennifer K., Daly, Steven Ross, Shine, David B., Lichttenegger, Gary, Bishop, Jean M., Yeo, Nick, Narciso, Hugh
• Primary Examiner(s): Shay, David
• Application Number:
  US11/834,572
• Publication Number:
  US 20080033519A1
• Time in Patent Office: 4,390 Days
• Field of Search: 606 7, 606 10- 18, 607 88- 93
• CPC Class Codes: A61B 2018/2261 with scattering, diffusion or dispersion of light
• CPC Class Codes: A61N 2005/0602 for treatment of blood vessels
• CPC Class Codes: A61N 2005/063 comprising light transmitting means, e.g. optical fibres
• CPC Class Codes: A61N 2005/0652 Arrays of diodes
• CPC Class Codes: A61N 5/0601 Apparatus for use inside the body
• CPC Class Codes: A61N 5/062 Photodynamic therapy, i.e. excitation of an agent

Abstract

Light sources are incorporated into a guidewire for enabling the ability to render light therapy be added to catheters that do not have that capability. In one exemplary embodiment, a solid guidewire includes a conductive core, and light sources are added to compartments formed in a distal end of the guidewire. In another exemplary embodiment, a light source array is included in a distal end of a hollow guidewire. A plurality of openings are formed into the walls of the hollow guidewire surrounding the array, enabling light to pass through the openings. Conductors extend from the array though the hollow center of the guidewire, to a proximal end of the hollow guidewire. The hollow guidewire can be coated with a conductive material, so that the coating on the guidewire serves as a conductor.

Claims

1. A light emitting guidewire comprising:

a flexible integrated guidewire, comprising;

a hollow tube, having a proximal and a distal end;

a first conductive path disposed within the hollow tube from the proximal to the distal end comprising a first wire; and

a second conductive path disposed within the hollow tube from the proximal to the distal end and comprising a second wire;

a plurality of light sources disposed at the distal end of the tube; and

an external power supply energizing the plurality of light sources;

wherein the first and the second conductive paths are configured to electrically couple the plurality of light sources to the external power supply and supply illuminating power to the plurality of light sources, and

wherein at least one of the first and the second conductive paths comprises a crenellated configuration.

2. The light emitting guidewire of claim 1, wherein the guidewire comprises at least one compartment formed into the distal end of the guidewire, the at least one compartment being sized and shaped to accommodate the plurality of light sources.

3. The light emitting guidewire of claim 2, wherein the at least one compartment comprises a plurality of compartments, such that each different light source is disposed in a corresponding different compartment.

4. The light emitting guidewire of claim 3, wherein the plurality of compartments are configured to function as a strain relief feature, to enhance a flexibility of the guidewire.

5. The light emitting guidewire of claim 1, wherein the hollow tube further comprises a plurality of openings disposed proximate to the distal end of the tube, and

wherein the plurality of light sources comprises a light source array disposed within the hollow tube, such that the plurality of openings encompass the array.

6. The light emitting guidewire of claim 5, wherein the array is encapsulated in a potting material that is electrically insulating and optically transparent to the light emitted by the array.

7. The light emitting guidewire of claim 1, further comprising a plurality of compartments formed into the distal end of the guidewire, each compartment being sized and shaped to accommodate at least one light source in a light source array at the distal end.

8. The light emitting guidewire of claim 7, wherein the plurality of compartments are configured linearly.

9. The light emitting guidewire of claim 1, further comprising an electrical lead and an insulating layer, the electrical lead defining at least one of the conductive paths, and the insulating layer is configured to encapsulate and insulate the electrical lead.

10. The light emitting guidewire of claim 9, wherein the insulating layer comprises a portion covering at least one light source, the portion being configured to transmit light emitted by the plurality of light sources.

11. The light emitting guidewire of claim 9, wherein the insulating layer comprise additives configured to enhance a distribution of light from the plurality of light sources.