Device for measuring bio information and method for manufacturing the same

• US 10,383,558 B2
• Filed: 03/07/2016
• Issued: 08/20/2019
• Est. Priority Date: 03/06/2015
• Status: Active Grant

• Current Assignee: Samsung Electronics Co. Ltd.
• Original Assignee: Samsung Electronics Co. Ltd.
• Inventors: Cho, Seong-Je, Kim, Kwang-Bok, Cho, Jae-Geol, Cho, Chul-Ho, Choi, Hyoung-Seon, Kang, Seok-Gin, Jung, Sun-Tae
• Primary Examiner(s): Bloch, Michael R
• Application Number:
  US15/063,003
• Publication Number:
  US 20160256091A1
• Time in Patent Office: 1,261 Days
• Field of Search: None
• CPC Class Codes: A61B 2562/125 characterised by the manufacture of electrodes
• CPC Class Codes: A61B 5/01 Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue clinical contact thermometers G01K13/20
• CPC Class Codes: A61B 5/021 Measuring pressure in heart or blood vessels A61B5/0205 takes precedence
• CPC Class Codes: A61B 5/024 Detecting, measuring or recording pulse rate or heart rate A61B5/0205, A61B5/021 take precedence
• CPC Class Codes: A61B 5/14546 for measuring analytes not otherwise provided for, e.g. ions, cytochromes
• CPC Class Codes: A61B 5/14865 invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
• CPC Class Codes: A61B 5/318 Heart-related electrical modalities, e.g. electrocardiography [ECG]
• CPC Class Codes: A61B 5/6824 Arm or wrist
• CPC Class Codes: A61B 5/6848 Needles

Abstract

A bio information measuring device is provided. The bio information measuring device includes a sensor portion and a needle portion including a plurality of needles projecting from a plurality of openings formed in a surface of the sensor portion. The plurality of needles are configured to pierce tissue, wherein the plurality of needles include a biocompatible organic material which includes an enzyme member that reacts with an analysis material and a conductive polymer for transferring an electrical signal generated as a result of a reaction of the enzyme member with the analysis material.

Claims

1. A bio information measuring device, comprising:

a sensor portion including a substrate portion having a first space portion and a housing stacked on top of the substrate portion; and

a needle portion including a needle portion base and a plurality of needles projecting from a plurality of openings formed in a surface of the sensor portion, the plurality of needles configured to pierce tissue,

wherein the plurality of needles include a biocompatible organic material which includes an enzyme member that reacts with an analysis material and a conductive polymer for transferring an electrical signal generated as a result of a reaction of the enzyme member with the analysis material,

wherein the housing includes a second space portion connected to the first space portion, and

wherein the needle portion base is configured to fill the first space portion and the second space portion.

2. The bio information measuring device of claim 1, wherein the plurality of needles are formed using at least one of electrical polymerization, thermal polymerization, photo polymerization, acid polymerization, and base polymerization.

3. The bio information measuring device of claim 1, wherein the biocompatible organic material further includes a filler.

4. The bio information measuring device of claim 1, wherein the substrate portion further includes a main substrate and an electrode portion provided on at least one of a first surface of the main substrate and a second surface of the main substrate, and wherein the first surface of the main substrate and the second surface of the main substrate are disposed in opposing relation to one another.

5. The bio information measuring device of claim 4, wherein the electrode portion includes a first electrode that is provided on at least one of the first surface of the main substrate and the second surface of the main substrate, wherein the first electrode is electrically connected to the needle portion and a second electrode that is provided on the other one of the first surface of the main substrate and the second surface of the main substrate, and wherein the second electrode is connected to an external connector terminal of the bio information measuring device.

6. The bio information measuring device of claim 5, wherein the first space portion of the substrate portion includes a receiving portion formed on the main substrate, a first opening formed on the first electrode and connecting the second space portion with the receiving portion, and a second opening formed on the second electrode, connected to the receiving portion, and configured for injecting one of a first member and a second member.

7. The bio information measuring device of claim 6, wherein each of the first opening and the second opening includes an inlet for injecting the biocompatible organic material including the enzyme member and the conductive polymer into the receiving portion and an outlet for discharging air from the receiving portion as the biocompatible organic material including the enzyme member and the conductive polymer is injected.

8. The bio information measuring device of claim 6, wherein the receiving portion includes a reservoir.

9. The bio information measuring device of claim 5, wherein the electrode portion includes a working electrode as the first electrode and a counter electrode as the second electrode that is positioned around the working electrode.

10. The bio information measuring device of claim 9, wherein a first needle portion included in the needle portion projects on a working electrode area that is connected to the working electrode, and a second needle portion included in the needle portion, which is connected to the counter electrode, projects on a counter electrode area corresponding to a position of the counter electrode.

11. The bio information measuring device of claim 10, wherein the first needle portion and the second needle portion in the needle portion are a single body formed of the biocompatible organic material including the enzyme member and the conductive polymer.

12. The bio information measuring device of claim 9, wherein the electrode portion includes three electrodes, a first needle portion included in the needle portion projects on a working electrode area connected to the working electrode, a second needle portion included in the needle portion projects on a counter electrode area corresponding to a position of the counter electrode around the working electrode area, and a third needle portion included in the needle portion connected to the a reference electrode projects on a reference electrode area corresponding to a position of the reference electrode and neighbors the working electrode area.

13. The bio information measuring device of claim 12, wherein the first needle portion, the second needle portion, and the third needle portion in the needle portion are a single body formed of the biocompatible organic material including the enzyme member and the conductive polymer.

14. The bio information measuring device of claim 9, wherein the second space portion forms a partitioned space of a region corresponding to a position of the working electrode and a region corresponding to either a position of a reference electrode or a position of the counter electrode.

15. The bio information measuring device of claim 14, wherein the second space portion is divided into a first partitioned space and a second partitioned space,

wherein the first partitioned space is provided on the first electrode and the needle portion base fills an area on the working electrode with the biocompatible organic material including the enzyme member and the conductive polymer, and

wherein the second partitioned space neighbors the first partitioned space and the needle portion base fills an area on the counter electrode with at least one of the biocompatible organic material including the enzyme member and the conductive polymer, or the biocompatible organic material including the conductive polymer.

16. The bio information measuring device of claim 14, wherein the electrode portion includes three electrodes, the second space portion is divided into a first partitioned space, a second partitioned space, and a third partitioned space,

wherein the first partitioned space is provided on the first electrode and the needle portion base fills an area on the working electrode with the biocompatible organic material including the enzyme member and the conductive polymer,

wherein the second partitioned space is positioned around the first partitioned space and the needle portion base fills an area on the counter electrode with at least one of the biocompatible organic material including the enzyme member and the conductive polymer, or the biocompatible organic material including the conductive polymer, and

wherein the third partitioned space neighbors the first partitioned space and the second partitioned space and the needle portion base fills an area on the reference electrode with at least one of the biocompatible organic material including the enzyme member and the conductive polymer, or the biocompatible organic material including the conductive polymer.

17. The bio information measuring device of claim 1, wherein the housing includes a first body and a second body,

wherein the first body is formed on the substrate portion and forms the second space portion, and

wherein the second body is formed on the first body, the second body including the plurality of openings for connecting to the second space portion and fastening the plurality of needles to the first body.