Infusion pump and method to enhance long term medication delivery accuracy

• US 10,384,004 B2
• Filed: 05/23/2017
• Issued: 08/20/2019
• Est. Priority Date: 01/21/2013
• Status: Active Grant

• Current Assignee: Baxter International Inc.
• Original Assignee: Baxter International Inc.
• Inventors: Zhu, Hong
• Primary Examiner(s): Hulbert, Amanda K
• Assistant Examiner(s): Edwards, Philip C
• Application Number:
  US15/602,680
• Publication Number:
  US 20170252512A1
• Time in Patent Office: Days
• Field of Search: 607 67
• CPC Class Codes: A61M 2005/14208 with a programmable infusion control system, characterised by the infusion program
• CPC Class Codes: A61M 2005/14506 mechanically driven, e.g. spring or clockwork
• CPC Class Codes: A61M 2205/14 Detection of the presence or absence of a tube, a connector or a container in an apparatus
• CPC Class Codes: A61M 2205/3331 Pressure; Flow
• CPC Class Codes: A61M 2205/3334 Measuring or controlling the flow rate
• CPC Class Codes: A61M 2205/3341 stabilising pressure or flow to avoid excessive variation
• CPC Class Codes: A61M 2205/3355 Controlling downstream pump pressure
• CPC Class Codes: A61M 2205/702 automatically during use
• CPC Class Codes: A61M 5/14212 Pumping with an aspiration and an expulsion action
• CPC Class Codes: A61M 5/14228 with linear peristaltic action, i.e. comprising at least three pressurising members or a helical member
• CPC Class Codes: A61M 5/1454 spring-actuated, e.g. by a clockwork
• CPC Class Codes: A61M 5/16831 Monitoring, detecting, signalling or eliminating infusion flow anomalies low-level float-valves causing cut-off A61M5/40; indicating or recording presence, absence or direction of flow in general G01P13/0066
• CPC Class Codes: A61M 5/172 electrical or electronic A61M5/16804, A61M5/16831 take precedence
• CPC Class Codes: A61M 5/1723 using feedback of body parameters, e.g. blood-sugar, pressure measurement of body parameters A61B5/00
• CPC Class Codes: G16H 20/17 delivered via infusion or injection

Abstract

Processes for operating an infusion pump are provided for pumping fluid though an administration set at a constant flow rate. The pump includes a pumping mechanism for pumping fluid and operates at a pulse frequency, and a controller controls the pulse frequency. Additionally, the pump has one or more sensors configured for measuring at least one characteristic value relating to a status of the infusion pump. The controller is configured for causing the pumping mechanism to operate at a first pulse frequency, and the one or more sensors measure the characteristic value. When the measured characteristic value meets a threshold value, the controller causes the pumping mechanism to operate at a second pulse frequency different from the first pulse frequency.

Claims

1. A process for operating an infusion pump at a constant flow rate over a long duration, the process comprising:

pumping fluid with a pumping mechanism through an administration set at a first pulse frequency, wherein said pulse frequency is controlled by a controller;

inputting a material used to form the administration set to the controller;

measuring at least one characteristic value relating to a status of said pumping mechanism;

comparing said at least one characteristic value with a threshold value;

causing said pumping mechanism to operate at a second pulse frequency when said at least one characteristic value at least meets said threshold value, said second pulse frequency being different from said first pulse frequency, wherein said threshold value is an elapsed time; and

,

calculating said threshold value based, at least in part, upon the material used to form the administration set.

2. The process of claim 1, further comprising:

calculating said threshold value based, at least in part, on a flow rate.

3. The process of claim 2, further comprising:

inputting the flow rate to the controller.

4. The process of claim 1, wherein the step of calculating said threshold value further includes:

adjusting a feedforward time delay based upon a normalization ratio.

5. The process of claim 1 further comprising:

comparing said at least one characteristic value with a second threshold value different than said first threshold value; and

,

causing said pumping mechanism to operate at a third pulse frequency when said at least one characteristic value at least meets said second threshold value, said third pulse frequency being greater than said first pulse frequency and said second pulse frequency.

6. The process of claim 1 further comprising:

causing said pumping mechanism to stop pumping if an ambient temperature is less than about 15°

C. or if said ambient temperature is greater than about 38°

C.

7. A process for operating an infusion pump for pumping fluid though an administration set at a constant flow rate over a long duration, the process comprising:

pumping fluid at a first pulse frequency with a pumping mechanism through an administration set by compressing said administration set, wherein said pulse frequency is controlled by a controller;

inputting a material used to form the administration set to the controller;

measuring a springback force of the administration set after being compressed by said pumping mechanism with at least one pressure sensor;

comparing said springback force with a threshold value;

causing said pumping mechanism to operate at a second pulse frequency when said springback force is less than said threshold value, said second pulse frequency being different from said first pulse frequency; and

,

calculating said threshold value based, at least in part, upon the material used to form the administration set.

8. The process of claim 7 further comprising:

comparing said springback force with a second threshold value different than said first threshold value; and

,

causing said pumping mechanism to operate at a third pulse frequency when said springback force is less than said second threshold value, said third pulse frequency being greater than said first pulse frequency and said second pulse frequency.

9. The process of claim 7 further comprising:

causing said pumping mechanism to stop pumping if an ambient temperature is less than about 15°

C. or if said ambient temperature is greater than about 38°

C.

10. The process of claim 7, wherein said springback force is measured while the administration set contains fluid.

11. A process for operating an infusion pump for pumping fluid though an administration set at a constant flow rate over a long duration, the process comprising:

pumping fluid with a pumping mechanism through an administration set at a first pulse frequency, wherein said pulse frequency is controlled by a controller;

inputting at least one of a flow rate and a material used to form the administration set to the controller;

measuring at least one characteristic value relating to a status of said pumping mechanism with at least one sensor;

comparing said at least one characteristic value with a threshold value;

causing said pumping mechanism to operate at a second pulse frequency when said at least one characteristic value at least meets said threshold value, said second pulse frequency being different from said first pulse frequency;

after causing said pumping mechanism to operate at the second pulse frequency;

comparing said at least one characteristic value with a second threshold value different than said first threshold value; and

,

causing said pumping mechanism to operate at a third pulse frequency when said at least one characteristic value at least meets said second threshold value, said third pulse frequency being greater than said first pulse frequency and said second pulse frequency; and

,

calculating said first threshold value and said second threshold value based upon at least one of the material used to form the administration set and the flow rate.

12. The process of claim 11 further comprising:

temporarily increasing said first pulse frequency or said second pulse frequency to allow for an increased flow rate for the duration of pumping approximately 1 ml of the fluid.

13. The process of claim 11 further comprising:

causing said pumping mechanism to stop pumping if an ambient temperature is less than about 15°

C. or if said ambient temperature is greater than about 38°

C.