Sensing system for detecting a piston in a medical fluid container

• US 10,384,014 B2
• Filed: 08/27/2015
• Issued: 08/20/2019
• Est. Priority Date: 09/02/2014
• Status: Active Grant

• Current Assignee: Eli Lilly and Company
• Original Assignee: Eli Lilly and Company
• Inventors: Forlani, Christian Fabio, Massari, Rossano Claudio, Mojarrad, Mehran
• Primary Examiner(s): Carpenter, William R
• Application Number:
  US15/505,699
• Publication Number:
  US 20170246399A1
• Time in Patent Office: 1,454 Days
• CPC Class Codes: A61M 2005/3126 Specific display means related to dosing
• CPC Class Codes: A61M 2205/3306 Optical measuring means
• CPC Class Codes: A61M 2205/3389 Continuous level detection A61M2205/3393 takes precedence
• CPC Class Codes: A61M 2205/587 Lighting arrangements
• CPC Class Codes: A61M 5/1452 pressurised by means of pistons
• CPC Class Codes: A61M 5/1684 by detecting the amount of infusate remaining, e.g. signalling end of infusion
• CPC Class Codes: A61M 5/20 Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically A61M5/142 , A61M5/46 take precedence; hypodermic projectiles F42B12/54
• CPC Class Codes: A61M 5/3129 Syringe barrels A61M5/3205 and A61M5/50 take precedence
• CPC Class Codes: A61M 5/31568 Means keeping track of the total dose administered, e.g. since the cartridge was inserted

Abstract

A sensing system for determining a position of a plunger within a fluid container. The sensing system includes a light source, a light detector and a controller. The light source is configured to emit light into a barrel wall of the fluid container so that the barrel wall serves as a waveguide to guide the light to travel therein in an axial direction. The light detector is positioned to detect reflected light that was emitted by the light source, traveled through the barrel wall serving as the waveguide, and then reflected off a surface of the plunger. The controller is in communication with the light detector to determine an axial position of the plunger surface based on data from the light detector of the detected reflected light.

Claims

1. A medication delivery device comprising:

a housing including a container retainer;

a medication container held within the container retainer, the medication container including a barrel and a plunger, the barrel made of a light transmitting material and extending in an axial direction between a forward outlet end and a rearward end, the plunger having at least one peripheral surface region in fluid tight engagement with an interior surface of a wall of the barrel to seal medication in the barrel forward of the plunger;

an advancing mechanism within said housing operable to advance said plunger within said barrel to dispense medication from the medication container through said forward outlet end;

a light source mounted within said housing proximate the rearward end of said barrel and configured to emit light directly into a thickness of the barrel wall, the barrel wall configured to serve as a waveguide to guide the light to travel therein in the axial direction, and wherein said light source is a single light emitting diode;

a light detector mounted within the container retainer and arranged to extend along a length of the barrel to detect reflected light that was emitted by the light source, traveled through the barrel wall serving as the waveguide,

a controller mounted within the housing in communication with said light detector to determine an axial position of the at least one peripheral surface region within the medication container based on data from said light detector of said detected reflected light.

2. The medication delivery device of claim 1 wherein said light source is configured to direct light into an axial end face of the barrel wall at the rearward end.

3. The medication delivery device of claim 1 further comprising an axially extending light filtering element positioned between said light detector and said barrel wall.

4. The medication delivery device of claim 1 wherein said light source is configured to direct light into a protuberance integrally formed with the barrel wall and projecting therefrom in a radial direction to the thickness of the barrel wall where the light is guided to travel therein in the axial direction.

5. The sensing system of claim 4, wherein the protuberance extends continuously around a circumference of the barrel wall.

6. The sensing system of claim 4, wherein the said light source is configured to direct light into the protuberance that projects radially outward from the barrel wall.

7. The sensing system of claim 6, wherein said protuberance comprises a finger grippable flange of the barrel wall, wherein said flange extends continuously around a circumference of the barrel wall.

8. The medication delivery device of claim 1 further comprising a display in electronic communication with said controller for indicating information determined based on said axial position of said at least one peripheral surface region.

9. The medication delivery device of claim 1 further comprising an actuator accessible externally of the housing and manually operable to control operation of said advancing mechanism.

10. The medication delivery device of claim 1 further comprising a first light polarizing filter and a second light polarizing filter, said first and second light polarizing filters oriented transverse to each other, said first light polarizing filter disposed between said light detector and said container, said second light polarizing filter arranged on said container retainer over said container to restrict ambient light.

11. The medication delivery device of claim 1 wherein said light source emits light into the barrel wall through a fiber optic, light pipe or wave guide disposed therebetween.

12. The medication delivery device of claim 1 wherein said light detector is mounted within the container retainer to detect reflected light that was emitted by the light source, traveled through the barrel wall serving as the waveguide, and then reflected off a neck section of the barrel at the forward outlet end, said detected reflected light associated with said neck section being used by said controller with the determined axial position of the at least one peripheral surface region to calculate an amount of medication remaining in the medication container.

13. The sensing system of claim 1, wherein said light source is positioned to emit light directly at a middle of the thickness of the barrel wall as measured in a radial direction.

14. The sensing system of claim 13, wherein said light source is positioned to be centered on the thickness of the barrel wall.

15. The sensing system of claim 1, wherein said light detector is positioned in close proximity to an outer periphery of said barrel.

16. The sensing system of claim 1, wherein the at least one peripheral surface region comprises first and second peripheral surface regions spaced in the axial direction, and wherein said controller determines a first axial position of the first peripheral surface region and a second axial position of the second peripheral surface region, said controller configured to determine a plunger compression based on the first and second axial positions.

17. The sensing system of claim 1, wherein said light detector is configured to extend around the barrel wall.

18. The sensing system of claim 17, wherein said light detector has a helical configuration.

19. A medication delivery device comprising:

a housing including a container retainer;

a medication container disposed within the container retainer, the medication container including a barrel and a plunger, the barrel comprising a light transmitting material and extending in an axial direction between a forward outlet end and a rearward end, the plunger having at least one peripheral surface region in fluid tight engagement with an interior surface of a wall of the barrel to seal medication in the barrel forward of the plunger;

an advancing mechanism disposed within said housing and operable to advance said plunger within said barrel to dispense medication from the medication container through said forward outlet end;

a light source disposed within said housing and configured to emit light directly into the barrel wall, the barrel wall configured to serve as a waveguide to guide the light to travel therein in the axial direction;

a light detector disposed within the container retainer and configured to detect light that was emitted by the light source and reflected off the at least one peripheral surface region after the light traveled axially through the barrel wall;

a first light polarizing filter and a second light polarizing filter, said first and second light polarizing filters oriented transverse to each other, said first light polarizing filter disposed between said light detector and said container, said second light polarizing filter arranged on said container retainer over said container to restrict ambient light; and

a controller disposed within the housing in communication with said light detector, the controller configured to determine an axial position of the at least one peripheral surface region within the medication container based on data from said light detector of said detected reflected light.

20. The medication delivery device of claim 19, wherein said light source is configured to direct light into an axial end face of the barrel wall at the rearward end.

21. The medication delivery device of claim 19, wherein said light source is configured to direct light into a protuberance integrally formed with the barrel wall and projecting therefrom in an inner radial direction.

22. The medication delivery device of claim 19, wherein said light source is configured to direct light into a protuberance integrally formed with the barrel wall and projecting therefrom in an outer radial direction.

23. A medication delivery device comprising:

a housing including a container retainer;

a medication container held within the container retainer, the medication container including a barrel and a plunger, the barrel made of a light transmitting material and extending in an axial direction between a forward outlet end and a rearward end, the plunger having at least one peripheral surface region in fluid tight engagement with an interior surface of a wall of the barrel to seal medication in the barrel forward of the plunger;

an advancing mechanism within said housing operable to advance said plunger within said barrel to dispense medication from the medication container through said forward outlet end;

a light source disposed within said housing proximate the rearward end of said barrel and configured to emit light centered on a middle of a radial thickness of the barrel wall, the barrel wall configured to serve as a waveguide to guide the light to travel therein in the axial direction;

a light detector disposed within the container retainer and arranged to extend along a length of the barrel, the light detector configured to detect light that was emitted by the light source and reflected off the at least one peripheral surface region after the light traveled axially through the barrel wall; and

a controller disposed within the housing in communication with said light detector, said controller configured to determine an axial position of the at least one peripheral surface region within the medication container based on data from said light detector of said detected reflected light.

24. The medication delivery device of claim 23, wherein said light source is configured to direct light into an axial end face of the barrel wall at the rearward end.

25. The medication delivery device of claim 23, wherein said light source is configured to direct light into a protuberance integrally formed with the barrel wall and projecting therefrom in an inner radial direction.

26. The medication delivery device of claim 23, wherein said light source is configured to direct light into a protuberance integrally formed with the barrel wall and projecting therefrom in an outer radial direction.