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Chemical sensing system

  • US 10,386,379 B1
  • Filed: 01/29/2019
  • Issued: 08/20/2019
  • Est. Priority Date: 01/29/2018
  • Status: Active Grant
First Claim
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1. A chemical sensing system, comprising:

  • a plurality of sensors arranged on at least one substrate, wherein a first sensor and a second sensor of the plurality of sensors have different sensitivities to sense at least one analyte in a sample, each of the plurality of sensors being configured to output a signal in response to sensing the at least one analyte; and

    a computer processor programmed to;

    receive the signals output from the plurality of sensors;

    determine a concentration of the at least one analyte in the sample by;

    providing the received signals as input to a first model trained to relate the signals output from the plurality of sensors to a feature representation to generate feature representation values;

    providing the feature representation values as input to a second model trained to relate the feature representation to a latent representation to generate latent representation values, the latent representation having a lower dimensionality than the feature representation;

    providing the latent representation values as input to a third model trained to relate the latent representation to a straightened orthogonal representation to generate straightened orthogonal representation values, wherein;

    one-dimensional manifolds in the straightened orthogonal representation corresponding to varying concentrations of a same analyte have zero angle between them; and

    one-dimensional manifolds in the straightened orthogonal representation corresponding to different analytes are orthogonal;

    providing the straightened orthogonal representation values as input to a fourth model trained to relate the straightened orthogonal representation to an output representation having bases corresponding to analytes, the analytes including the at least one analyte; and

    determining the concentration of the at least one analyte in the sample based on an output of the fourth model; and

    provide an indication of the determined concentration of the at least one analyte in the sample to a user.

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