Methods and systems for determining intraocular pressure

• US 10,386,640 B2
• Filed: 09/19/2016
• Issued: 08/20/2019
• Est. Priority Date: 03/16/2015
• Status: Active Grant

• Current Assignee: Magic Leap, Inc.
• Original Assignee: Magic Leap, Inc.
• Inventors: Samec, Nicole Elizabeth, Macnamara, John Graham, Harrises, Christopher M., Schowengerdt, Brian T., Abovitz, Rony, Baerenrodt, Mark
• Primary Examiner(s): Du, Haixia
• Application Number:
  US15/269,376
• Publication Number:
  US 20170000345A1
• Time in Patent Office: 1,065 Days
• CPC Class Codes: A61B 2562/0204 Acoustic sensors
• CPC Class Codes: A61B 2562/0219 Inertial sensors, e.g. accelerometers, gyroscopes, tilt switches
• CPC Class Codes: A61B 2562/0247 Pressure sensors
• CPC Class Codes: A61B 3/0008 provided with illuminating means A61B3/117 takes precedence; goniolenses used for laser treatment A61F9/009; illuminating means for optical instruments G02B27/00
• CPC Class Codes: A61B 3/0025 characterised by electronic signal processing, e.g. eye models
• CPC Class Codes: A61B 3/005 Constructional features of the display
• CPC Class Codes: A61B 3/022 for testing contrast sensitivity
• CPC Class Codes: A61B 3/024 for determining the visual field, e.g. perimeter types
• CPC Class Codes: A61B 3/028 for testing visual acuity; for determination of refraction, e.g. phoropters
• CPC Class Codes: A61B 3/0285 Phoropters
• CPC Class Codes: A61B 3/032 Devices for presenting test symbols or characters, e.g. test chart projectors A61B3/036 takes precedence
• CPC Class Codes: A61B 3/036 for testing astigmatism
• CPC Class Codes: A61B 3/063 for testing light sensitivity, i.e. adaptation
• CPC Class Codes: A61B 3/066 for testing colour vision
• CPC Class Codes: A61B 3/08 for testing binocular or stereoscopic vision, e.g. strabismus
• CPC Class Codes: A61B 3/085 for testing strabismus
• CPC Class Codes: A61B 3/10 Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
• CPC Class Codes: A61B 3/1005 for measuring distances inside the eye, e.g. thickness of the cornea A61B3/11 takes precedence
• CPC Class Codes: A61B 3/101 for examining the tear film
• CPC Class Codes: A61B 3/1015 for wavefront analysis
• CPC Class Codes: A61B 3/102 : for optical coherence tomography [OCT]
• CPC Class Codes: A61B 3/1035 : for measuring astigmatism testing astigmatism A61B3/036
• CPC Class Codes: A61B 3/113 : for determining or recording eye movement
• CPC Class Codes: A61B 3/12 : for looking at the eye fundus, e.g. ophthalmoscopes A61B3/13 takes precedence
• CPC Class Codes: A61B 3/1216 : for diagnostics of the iris
• CPC Class Codes: A61B 3/1241 : specially adapted for observation of ocular blood flow, e.g. by fluorescein angiography
• CPC Class Codes: A61B 3/13 : Ophthalmic microscopes
• CPC Class Codes: A61B 3/14 : Arrangements specially adapted for eye photography apparatus or arrangements for taking photographs per se G03B
• CPC Class Codes: A61B 3/165 : Non-contacting tonometers
• CPC Class Codes: A61B 5/0059 : using light, e.g. diagnosis by transillumination, diascopy, fluorescence A61B5/0093, A61B5/1455, A61B5/02416 and A61B5/0261 take precedence
• CPC Class Codes: A61B 5/0066 : Optical coherence imaging
• CPC Class Codes: A61B 5/0077 : Devices for viewing the surface of the body, e.g. camera, magnifying lens
• CPC Class Codes: A61B 5/01 : Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue clinical contact thermometers G01K13/20
• CPC Class Codes: A61B 5/12 : Audiometering
• CPC Class Codes: A61B 5/14532 : for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/1455 : using optical sensors, e.g. spectral photometrical oximeters
• CPC Class Codes: A61B 5/14555 : specially adapted for the eye fundus
• CPC Class Codes: A61B 5/361 : Detecting fibrillation
• CPC Class Codes: A61B 5/369 : Electroencephalography [EEG] devices for psychotechnics A61B5/16
• CPC Class Codes: A61B 5/398 : Electrooculography [EOG], e.g. detecting nystagmus; Electroretinography [ERG]
• CPC Class Codes: A61B 5/6803 : Head-worn items, e.g. helmets, masks, headphones or goggles
• CPC Class Codes: A61B 8/10 : Eye inspection
• CPC Class Codes: A61B 8/461 : Displaying means of special interest
• CPC Class Codes: A61F 2007/0004 : Eyes or part of the face surrounding the eyes
• CPC Class Codes: A61F 2007/004 : Hip
• CPC Class Codes: A61F 2009/00863 : Retina
• CPC Class Codes: A61F 9/0026 : Ophthalmic product dispenser attachments to facilitate positioning near the eye
• CPC Class Codes: A61H 2201/165 : Wearable interfaces
• CPC Class Codes: A61M 2021/0022 : by the tactile sense, e.g. vibrations
• CPC Class Codes: A61M 2021/0027 : by the hearing sense
• CPC Class Codes: A61M 2021/0066 : with heating or cooling
• CPC Class Codes: A61M 21/02 : for inducing sleep or relaxation, e.g. by direct nerve stimulation, hypnosis, analgesia for massage A61H; electrotherapy A61N, e.g. applying alternating or intermittent electric currents for producing anaesthesia A61N1/36021
• CPC Class Codes: A61M 2205/3375 : Acoustical, e.g. ultrasonic, measuring means
• CPC Class Codes: A61M 2205/507 : Head Mounted Displays [HMD]
• CPC Class Codes: A61N 2005/0648 : the light being directed to the eyes
• CPC Class Codes: G02B 2027/0138 : comprising image capture systems, e.g. camera
• CPC Class Codes: G02B 2027/014 : comprising information/image processing systems
• CPC Class Codes: G02B 2027/0185 : Displaying image at variable distance
• CPC Class Codes: G02B 21/0032 : Optical details of illumination, e.g. light-sources, pinholes, beam splitters, slits, fibers G02B21/0036 - G02B21/008; means for illumination of specimens in general G02B21/06
• CPC Class Codes: G02B 27/0093 : with means for monitoring data relating to the user, e.g. head-tracking, eye-tracking
• CPC Class Codes: G02B 27/0172 : characterised by optical features
• CPC Class Codes: G02B 27/0179 : Display position adjusting means not related to the information to be displayed
• CPC Class Codes: G02C 7/027 : considering wearer's parameters
• CPC Class Codes: G06T 19/006 : Mixed reality object pose determination, tracking or camera calibration for mixed reality G06T7/00
• CPC Class Codes: G06T 2207/10024 : Color image
• CPC Class Codes: G06T 2207/10148 : Varying focus
• CPC Class Codes: G06T 2207/10152 : Varying illumination
• CPC Class Codes: G06T 2207/30041 : Eye; Retina; Ophthalmic
• CPC Class Codes: G16H 20/17 : delivered via infusion or injection
• CPC Class Codes: G16H 40/63 : for local operation
• CPC Class Codes: G16H 40/67 : for remote operation
• CPC Class Codes: G16H 50/20 : for computer-aided diagnosis, e.g. based on medical expert systems

Abstract

Configurations are disclosed for a health system to be used in various healthcare applications, e.g., for patient diagnostics, monitoring, and/or therapy. The health system may comprise a light generation module to transmit light or an image to a user, one or more sensors to detect a physiological parameter of the user'"'"'s body, including their eyes, and processing circuitry to analyze an input received in response to the presented images to determine one or more health conditions or defects.

Claims

1. A wearable augmented reality device comprising:

an augmented reality head-mounted ophthalmic system comprising a wearable augmented reality display platform configured to pass light from the world into an eye of a wearer wearing the head-mounted ophthalmic system;

a light source configured to project light into the eye of the wearer, wherein the projected light is configured to induce changes in accommodation or vergence of the eye; and

a light-monitoring device configured to measure light reflected from tissue of the eye,

wherein the augmented reality head-mounted ophthalmic system is configured to determine intraocular pressure from the measured reflected light, and wherein the measured reflected light encompasses glint characteristics associated with the induced changes in accommodation or vergence.

2. The device of claim 1, wherein the display platform comprises a fiber scanning display, wherein the light source is part of the fiber scanning display and is configured to project beams of light into the wearer'"'"'s eyes.

3. The device of claim 2, wherein the fiber length of the fiber scanning display is variable.

4. The device of claim 2, wherein the fiber scanning display comprises the light-monitoring device.

5. The device of claim 1, wherein the light-monitoring device comprises a photo-detector.

6. The device of claim 1, wherein the light source is configured to vary a wavelength of the light projected into the eye.

7. The device of claim 1, wherein the light source comprises an adaptable optics element configured to project the light into the wearer'"'"'s eye.

8. The device of claim 7, wherein the adaptable optics element comprises a variable focus element.

9. The device of claim 1, wherein the light-monitoring device is configured to measure backscattered light to determine intraocular pressure.

10. The device of claim 1, wherein the light-monitoring device is configured to detect on or more Purkinje images of the wearer'"'"'s eye.

11. The device of claim 10, wherein the head-mounted ophthalmic system is configured to determine intraocular pressure at least in part based on a shape or location of the one or more Purkinje images.

12. The device of claim 10, wherein the one or more Purkinje images comprises a glint.

13. The device of claim 1, wherein the ophthalmic system is further configured to detect the presence of ocular hypertension at least in part based on the determined intraocular pressure.

14. The device of claim 1, wherein the ophthalmic system is further configured to determine an ocular pulse rate at least in part based on comparing a plurality of intraocular pressures determined from measurements taken at a regular time interval.