Clot retrieval device for removing clot from a blood vessel

• US 10,390,850 B2
• Filed: 03/12/2014
• Issued: 08/27/2019
• Est. Priority Date: 03/14/2013
• Status: Active Grant

• Current Assignee: Neuravi Limited (Johnson & Johnson)
• Original Assignee: Neuravi Limited (Johnson & Johnson)
• Inventors: Vale, David, Brady, Eamon, Gilvarry, Michael, Razavi, Mahmood, McArdle, Kevin, Hardiman, David, Casey, Brendan
• Primary Examiner(s): Dornbusch, Dianne
• Application Number:
  US14/206,973
• Publication Number:
  US 20140371779A1
• Time in Patent Office: 1,994 Days
• CPC Class Codes: A61B 17/12109 in a blood vessel
• CPC Class Codes: A61B 17/221 Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions surgical snare instruments A61B17/32056
• CPC Class Codes: A61B 17/320725 with radially expandable cutting or abrading elements A61B17/32075 takes precedence
• CPC Class Codes: A61B 2017/00358 Snares for grasping
• CPC Class Codes: A61B 2017/00778 Operations on blood vessels A61B2017/22097, A61B2017/320741 take precedence
• CPC Class Codes: A61B 2017/22034 for gripping the obstruction or the tissue part from inside
• CPC Class Codes: A61B 2017/2212 having a closed distal end, e.g. a loop
• CPC Class Codes: A61B 2017/2215 having an open distal end
• CPC Class Codes: A61F 2/013 Distal protection devices, i.e. devices placed distally in combination with another endovascular procedure, e.g. angioplasty or stenting
• CPC Class Codes: A61M 29/00 Dilators with or without means for introducing media, e.g. remedies instruments for performing visual medical inspections of cavities or tubes of the body A61B1/00

Abstract

A clot retrieval device may include an elongate member and an expandable clot engaging element configured to extend across the clot in its expanded state. The expandable clot engaging element may include a first monolithic structure and a second monolithic structure. The first monolithic structure may encircle the second monolithic structure over at least a portion of its length. The second monolithic structure may include a proximal section, an intermediate section, and a distal section. The distal section may include an expansion.

Claims

1. A clot retrieval device comprising:

a shaft having a length extending between a shaft proximal end and a shaft distal end, and

an expandable clot engaging element expandable between a collapsed state and an expanded state, wherein the shaft is separate from the expandable clot engaging element, the expandable clot engaging element comprising;

a first portion having a distal end, a closed proximal end fixedly coupled longitudinally and rotationally to the shaft distal end, and a tubular section between the distal end and the closed proximal end, the tubular section configured to form a flow channel through a clot and tapering out from the closed proximal end;

a second portion coupled to the distal end of the first portion, the second portion comprising an open distal end larger than an open proximal end and extending distally of the distal end of the first portion in the expanded state, and

a distal net portion comprising a closed distal end and an open proximal end larger than distal end of the second portion, the open proximal end of the distal net portion coupled to the distal end of the second portion and distally extended therefrom, wherein the second portion includes a plurality of struts forming second portion cells and the distal net portion includes a plurality of struts forming a plurality of distal net cells smaller than the second portion cells;

the expandable clot engaging element having a length extending between the closed proximal end and the closed distal end, wherein the length of the shaft is longer than the length of the clot engaging element,

wherein in the expanded state, the second portion has a radial size larger than a radial size of the tubular section of the first portion.

2. The device of claim 1, wherein the first portion comprises a plurality of struts, wherein each strut of the plurality of struts at the proximal end of the first portion taper towards one another to form the closed proximal end.

3. The device of claim 1, wherein the shaft is a wire shaft separate from the expandable clot engaging element, wherein the first portion, the second portion, and the distal net are monolithic.

4. The device of claim 1, wherein the first portion includes a plurality of struts forming first portion cells smaller than the second portion cells.

5. The device of claim 1, wherein the density of the struts provided by the distal net portion is greater than the density of the struts provided by the first portion and second portion.

6. The device of claim 1, wherein the open proximal end of the distal net comprises a radial size larger than the second portion.

7. The device of claim 1, wherein in the expanded state, the tubular section of the first portion has a radial size between about 20% and about 60% of a radial size of the second portion.

8. The device of claim 1, wherein, in an unstressed configuration, the first portion extends along a first portion axis that is straight and collinear with the shaft.

9. The device of claim 1, wherein one or more clot engaging petals protrude from the second portion, the one or more petals being separated longitudinally along an outer surface of the second portion and are configured to fit within cells of the outer portion and expand outward to a larger radial size than that of the second portion.

10. The device of claim 1, wherein one or more clot engaging petals protrude from the second portion, the one or more petals being separated longitudinally and radially along an outer surface of the second portion and are configured to engage with and grip the clot to retain it securely for retraction.

11. A clot retrieval device comprising:

a shaft having a length extending between a shaft proximal end and a shaft distal end; and

a self-expandable clot engaging element separate from the shaft and expandable between a collapsed state and an expanded state, the expandable clot engaging element comprising;

a first portion having a distal end and a proximal end coupled to and longitudinally fixed to the shaft distal end such that the clot engaging element extends distally of a distalmost end of the shaft distal end, the first portion configured to form a flow channel through a clot and comprising;

a proximal taper section extending from the shaft; and

a tubular section extending from the proximal taper section,

a second portion coupled to the proximal end of the first portion, the second portion comprising an open distal end larger than an open proximal end and extending distally of the first portion in the expanded state, and

a distal net portion comprises a closed distal end and a proximal end larger than distal end of the second portion, the proximal end of the distal net portion coupled to a distal end of the second portion and distally extended therefrom, wherein the second portion is positioned between the first portion and the distal net portion,

wherein the second portion includes a plurality of struts forming second portion cells and the distal net portion includes a plurality of struts forming a plurality of distal net cells smaller than the second portion cells

the self-expandable clot engaging element having a length extending between the proximal end of the first portion and the closed distal end of the distal net portion, wherein the length of the shaft is longer than the length of the clot engaging element,

wherein in the expanded state, the tubular section of the first portion has a radial size between about 20% and about 60% of a radial size of the second portion.

12. The device of claim 11, wherein the first portion, the second portion, and the distal net portion of the expandable clot engaging element comprise a monolithic one-piece structure.

13. The device of claim 11, wherein each of the first portion and the second portion are substantially cylindrical, wherein the open proximal end of the distal net comprises a radial size larger than the second portion.

14. The device of claim 11, wherein the first portion includes a plurality of struts forming first portion cell smaller than the second portion cells.

15. The device of claim 11, wherein, in an unstressed configuration, the first portion extends along a first portion axis that is straight and collinear with the shaft.

16. A clot retrieval system comprising:

a sheath,

a shaft, wherein a portion of the shaft is received within a proximal portion of the sheath, and

a self-expandable clot engaging element separate from the shaft and expandable between a collapsed state and an expanded state, the self-expandable clot engaging element extends distally of a distalmost end the shaft, the self-expandable expandable clot engaging element comprising;

a first portion having a distal end, a proximal end fixed to a distal end of the shaft, and a tubular section disposed between the distal and proximal end, wherein in the expanded state the tubular section proximally tapers outward from the shaft,

a second portion coupled to the distal end of the first portion, the second portion comprising an open distal end larger than an open proximal end and extending distally of the distal end of the first portion in the expanded state, and

a distal net portion comprising a closed distal end and an open proximal end larger than the open distal end of the second portion, the open proximal end of the distal net portion coupled to the distal end of the second portion and distally extended therefrom, wherein the second portion includes a plurality of struts forming second portion cells and the distal net portion includes a plurality of struts forming a plurality of distal net cells smaller than the second portion cells;

wherein in the expanded state, the second portion has a radial size larger than a radial size of the tubular section of the first portion, and

wherein each of the first portion, the second portion, and the distal net portion comprise a plurality of struts,

wherein the density of the struts provided by the distal net portion is greater than the density of the struts provided by the first portion and second portion.

17. The system of claim 16, wherein the tubular section of the first portion includes a plurality of struts in a substantially cylindrical shape forming first portion cells, the second portion includes the plurality of struts in a substantially cylindrical shape forming second portion cells, and the distal net portion includes the plurality of struts forming distal net cells.

18. The system of claim 17, wherein the second portion cells are larger than the first portion cells.

19. The system of claim 16, wherein in the expanded state, the first portion has a radial size between about 20% and about 60% of a radial size of the second portion.