Inner housing for a drug delivery device

• US 10,391,254 B2
• Filed: 07/29/2015
• Issued: 08/27/2019
• Est. Priority Date: 06/01/2009
• Status: Active Grant

• Current Assignee: Sanofi-Aventis Deutschland GmbH (Sanofi )
• Original Assignee: Sanofi-Aventis Deutschland GmbH (Sanofi )
• Inventors: Plumptre, David
• Primary Examiner(s): Stigell, Theodore J
• Application Number:
  US14/812,133
• Publication Number:
  US 20150328410A1
• Time in Patent Office: 1,490 Days
• CPC Class Codes: A61M 2005/3126 Specific display means related to dosing
• CPC Class Codes: A61M 2205/27 preventing use
• CPC Class Codes: A61M 5/31541 Means preventing setting of a dose beyond the amount remaining in the cartridge
• CPC Class Codes: A61M 5/31543 piston rod reset means, i.e. means for causing or facilitating retraction of piston rod to its starting position during cartridge change
• CPC Class Codes: A61M 5/31551 including axial movement of dose setting member
• CPC Class Codes: A61M 5/31585 performed by axially moving actuator, e.g. an injection button

Abstract

A dose setting mechanism for a drug delivery device is disclosed. The mechanism comprises an outer housing and an inner housing having an external groove. The inner housing guides a driver to dispense a set dose. A dial sleeve is disposed between the outer and inner housing and is rotatably engaged with the inner housing. When a dose is set, the dial sleeve is rotated and translates away from both the outer housing and the inner housing.

Claims

1. A dose setting mechanism for a drug delivery device, said dose setting mechanism comprising:

an outer housing;

an inner housing having an external groove, the inner housing having an inner surface comprising a mechanical configuration;

a driver;

a dial sleeve disposed between said outer housing and said inner housing, said dial sleeve being rotatably engaged with said external groove of said inner housing; and

a dose dial grip rotatably coupled to said dial sleeve, said dose dial grip being non-rotatably coupled to a dose button,

wherein, when a dose is set by rotating said dose dial grip of said dose setting mechanism, said dial sleeve and said driver are both rotated with respect to both said outer housing and said inner housing and said dial sleeve and said driver are both translated away from both said outer housing and said inner housing, and

wherein the mechanical configuration of the inner surface of the inner housing is configured to prevent rotation of said driver relative to said inner housing during dispensing of said dose set by said dose setting mechanism to guide said driver to dispense said dose.

2. The dose setting mechanism of claim 1, further comprising a spindle for acting on a cartridge bung, with the driver cooperating with said spindle, and the mechanical configuration of the inner housing dictating movement of said driver during dispensing of said dose so that said spindle acts on said cartridge bung.

3. The dose setting mechanism of claim 1, further comprising a clutch operatively coupled to said dial sleeve and said driver, said clutch allowing said dial sleeve and said driver to rotate together during a setting of said dose, and said clutch allowing relative rotation of said driver and said dial sleeve during dispensing of said dose.

4. The dose setting mechanism of claim 1, wherein said dose dial grip is non-rotatably coupled to the dose button, such that when said dose is set by rotating said dose dial grip of said dose setting mechanism, said dial sleeve is rotated with respect to both said outer housing and said inner housing and said dial sleeve is translated away from both said outer housing and said inner housing while said dose button does not rotate.

5. The dose setting mechanism of claim 1, wherein said mechanical configuration of said inner housing comprises a spline that guides said driver to dispense said dose set by said dose setting mechanism.

6. The dose setting mechanism of claim 1, wherein said mechanical configuration of said inner housing comprises a groove that guides said driver to dispense said dose set by said dose setting mechanism.

7. The dose setting mechanism of claim 1, wherein said external groove of said inner housing comprises a helical groove having a constant pitch.

8. The dose setting mechanism of claim 1, wherein said dial sleeve has a generally smooth outer surface.

9. The dose setting mechanism of claim 8, comprising a scale arrangement provided along a portion of said generally smooth outer surface.

10. The dose setting mechanism of claim 9, wherein said scale arrangement provided along said portion of said generally smoother outer surface is viewable only through a window provided in the outer housing of said dose setting mechanism.

11. The dose setting mechanism of claim 1, wherein said dose setting mechanism is coupled to a cartridge holder.

12. The dose setting mechanism of claim 11, wherein said dose setting mechanism is permanently coupled to the cartridge holder.

13. The dose setting mechanism of claim 1, comprising a spindle operatively coupled to said driver such that when said mechanical configuration of said inner housing guides said driver to dispense said dose set by said dose setting mechanism, said driver pushes said spindle to act on a bung of a cartridge while said spindle translates in a distal direction to expel said dose from said cartridge.

14. The dose setting mechanism of claim 1, wherein the inner surface of said inner housing comprises at least one longitudinal groove.

15. The dose setting mechanism of claim 1, wherein the inner surface of said inner housing comprises at least a portion of a helical groove.

16. The dose setting mechanism of claim 1, wherein the inner surface of said inner housing comprises a male groove guide.

17. The dose setting mechanism of claim 1, further comprising a spindle comprising at least one groove, said at least one groove cooperating with said driver to allow said spindle to translate in a distal direction to expel said dose from a cartridge.

18. The dose setting mechanism of claim 1, wherein the inner housing has a length in its axial direction which is substantially the same as a length of the dose setting mechanism.

19. The dose setting mechanism of claim 1, wherein the inner housing has a length in its axial direction which is substantially the same as a length of the outer housing or the dial sleeve.

20. The dose setting mechanism of claim 1, wherein the inner housing has a length in its axial direction which is substantially the same as a length of the dial sleeve.

21. A dose setting mechanism for a drug delivery device, said dose setting mechanism comprising:

an outer housing;

an inner housing having an external groove, said inner housing comprising an internal surface defining a spline or a groove;

a driver;

a dial sleeve disposed between said outer housing and said inner housing, said dial sleeve being rotatably engaged with said external groove of said inner housing; and

a dose dial grip rotatably coupled to said dial sleeve, said dose dial grip being non-rotatably coupled to a dose button,

wherein, when a dose is set by rotating said dose dial grip of said dose setting mechanism, said dial sleeve and driver are both rotated with respect to both said outer housing and said inner housing and are translated away from both said outer housing and said inner housing, and

wherein said spline or said groove of said inner housing is configured to guide said driver to dispense said dose set by said dose setting mechanism.