Methods, devices, systems, and compositions for detecting gases

• US 10,393,666 B2
• Filed: 03/12/2013
• Issued: 08/27/2019
• Est. Priority Date: 03/12/2012
• Status: Active Grant

• Current Assignee: Respirion, LLC
• Original Assignee: Respirion, LLC
• Inventors: Moretti, Eugene W., Wood, Robert Lavin, Shang, Allan Bruce, Yauch, Steven S.
• Primary Examiner(s): Alexander, Lyle
• Assistant Examiner(s): Gerido, Dwan A
• Application Number:
  US13/796,593
• Publication Number:
  US 20130259749A1
• Time in Patent Office: 2,359 Days
• CPC Class Codes: A61B 5/0836 Measuring rate of CO2 production
• CPC Class Codes: A61B 5/742 using visual displays A61B5/339 takes precedence
• CPC Class Codes: G01N 21/783 for analysing gases
• CPC Class Codes: Y10T 436/204998 Inorganic carbon compounds

Abstract

A method of monitoring a respiratory stream can be provided by monitoring color change of a color change material to determine a CO2 level of the respiratory stream in contact with the color change material by emitting visible light onto the color change material. Related devices, systems, and compositions are also disclosed.

Claims

1. A composition comprising:

a dye present in an amount of about 0.001% to about 0.1% by weight of the composition;

a buffer present in an amount of about 0.5% to about 10% by weight of the composition;

an alkaline material present in an amount of about 0.1% to about 10% by weight of the composition;

a nitrogen containing compound configured to provide an increase in a colorific response present in an amount of about 0.01% to about 2% by weight of the composition; and

a water-attractive component present in an amount of about 5% to about 50% by weight of the composition.

2. The composition of claim 1, further comprising an antimicrobial additive present in an amount of about 1 ppm to about 1000 ppm.

3. The composition of claim 1, further comprising a surface modifying additive present in an amount of about 0.1% to about 1% by weight of the composition.

4. The composition of claim 1, wherein said nitrogen containing compound is chosen from an amine, a quaternary ammonium compound, an amino acid, an amino acid derivative, and any combination thereof.

5. A color change material comprising:

a substrate; and

the color change composition of claim 1,

wherein said color change composition is in contact with at least a portion of the said substrate.

6. The color change material of claim 5, wherein said color change material is dry or partially hydrated.

7. The color change material of claim 5, wherein said substrate is optically transmissive.

8. A carbon dioxide indicator comprising:

a color change material comprising the color change composition of claim 1, wherein said color change material is responsive to carbon dioxide; and

a control material, wherein said control material is substantially non-responsive to carbon dioxide.

9. The carbon dioxide indicator of claim 8, wherein said color change material and said control material are configured to be exposed to substantially the same conditions.

10. The carbon dioxide indicator of claim 8, wherein said color change material is configured to change from a first color to a second color and return to said first color in response to contact with at least one carbon dioxide concentration.

11. The carbon dioxide indicator of claim 8, wherein said color change material is configured to change from a first color to a second color and return to said first color about 1 to about 60 times per minute in response to contact with at least two consecutive carbon dioxide concentrations.

12. The carbon dioxide indicator of claim 8, wherein in operation, said color change material and said control material are substantially the same color at a first CO₂ concentration prior to contact with a second CO₂ concentration having a greater CO₂ concentration.

13. The carbon dioxide indicator of claim 8, wherein said control material comprises a dye and is configured to be non-responsive to carbon dioxide by quenching said dye.

14. The carbon dioxide indicator of claim 8, wherein at least of a portion of said color change material is configured to provide a first color of a particular value and hue and said control material is printed to a second color that is substantially the same value and hue as the first color.

15. The composition of claim 1, wherein the composition, when applied to a portion of a substrate, is configured to change the portion of the substrate from a first color to a second color and return the portion of the substrate to the first color about 1 to about 60 times per minute in response to contact with at least two consecutive carbon dioxide concentrations.

16. The composition of claim 15, wherein the substrate is filter paper.

17. The composition of claim 1, wherein the composition has a pH of about 8 to about 10.

18. A composition comprising:

metacresol purple present in an amount of about 0.001% to about 0.1% by weight of the composition;

a buffer present in an amount of about 0.5% to about 10% by weight of the composition;

an alkaline material comprising a carbonate, the alkaline material present in an amount of about 0.1% to about 10% by weight of the composition;

monoethanolamine present in an amount of about 0.01% to about 2% by weight of the composition; and

a water-attractive component present in an amount of about 5% to about 50% by weight of the composition.

19. The composition of claim 18, wherein the composition, when applied to a portion of a substrate, is configured to change the portion of the substrate from a first color to a second color and return the portion of the substrate to the first color about 1 to about 60 times per minute in response to contact with at least two consecutive carbon dioxide concentrations.

20. The composition of claim 19, wherein the substrate is filter paper.

21. A carbon dioxide indicator comprising:

a color change material comprising a substrate and a color change composition that is in contact with at least a portion of said substrate, wherein said color change material is responsive to carbon dioxide; and

a control material, wherein said control material is substantially non-responsive to carbon dioxide,

wherein said substrate comprises filter paper and said color change material comprises;

metacresol purple present in an amount of about 0.001% to about 0.1% by weight of the composition;

a buffer present in an amount of about 0.5% to about 10% by weight of the composition;

an alkaline material comprising a carbonate, the alkaline material present in an amount of about 0.1% to about 10% by weight of the composition;

monoethanolamine present in an amount of about 0.01% to about 2% by weight of the composition; and

a water-attractive component present in an amount of about 5% to about 50% by weight of the composition.