Mitral prosthesis and methods for implantation

• US 10,398,546 B2
• Filed: 11/10/2016
• Issued: 09/03/2019
• Est. Priority Date: 02/24/2010
• Status: Active Grant

• Current Assignee: Medtronic Ventor Technologies LTD. (Medtronic Plc)
• Original Assignee: Medtronic Ventor Technologies LTD. (Medtronic Plc)
• Inventors: Tuval, Yossi
• Primary Examiner(s): Sharma, Yashita
• Assistant Examiner(s): Preston, Rebecca S
• Application Number:
  US15/348,144
• Publication Number:
  US 20170056167A1
• Time in Patent Office: 1,027 Days
• CPC Class Codes: A61F 2/2409 Support rings therefor, e.g. for connecting valves to tissue annuloplasty rings A61F2/2442
• CPC Class Codes: A61F 2/2412 with soft flexible valve members, e.g. tissue valves shaped like natural valves check valves with flexible valve members in general F16K15/14
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2/2436 Deployment by retracting a sheath
• CPC Class Codes: A61F 2002/8483 Barbs
• CPC Class Codes: A61F 2210/0004 bioabsorbable
• CPC Class Codes: A61F 2220/0016 with sharp anchoring protrusions, e.g. barbs, pins, spikes
• CPC Class Codes: A61F 2220/0075 sutured, ligatured or stitched, retained or tied with a rope, string, thread, wire or cable
• CPC Class Codes: A61F 2230/0006 circular
• CPC Class Codes: A61F 2230/0013 Horseshoe-shaped, e.g. crescent-shaped, C-shaped, U-shaped
• CPC Class Codes: A61F 2230/0069 cylindrical
• CPC Class Codes: A61F 2230/0078 hyperboloidal
• CPC Class Codes: A61F 2250/0039 differing in diameter
• CPC Class Codes: A61F 2250/006 modular

Abstract

A mitral valve prosthesis and methods for implanting the prosthesis transapically (i.e., through the apex of the heart), transatrially (i.e., through the left atrium of the heart), and transseptally (i.e., through the septum of the heart). The prosthesis generally includes a self-expanding frame and two or more support arms. A valve prosthesis is sutured to the self-expanding frame. Each support arm corresponds to a native mitral valve leaflet. At least one support arm immobilizes the native leaflets, and holds the native leaflets close to the main frame.

Claims

1. A heart valve prosthesis comprising:

a frame comprising an inner support structure including an expandable inflow section having an asymmetrical shape and an outer support structure coupled to the inner support structure, the outer support structure including a first commissure post and first and second engagement arms, wherein the first commissure post is parallel to a longitudinal axis of the inner support structure and wherein a first end of the first engagement arm is attached to the first commissure post and a first end of the second engagement arm is attached to the first commissure post; and

a valve structure attached to the frame within an interior area of the inner support structure.

2. The prosthesis of claim 1, wherein the inflow section comprises a plurality of cells.

3. The prosthesis of claim 1, wherein the frame further comprises an expandable outflow section.

4. The prosthesis of claim 3, wherein the outflow section comprises a plurality of cells.

5. The prosthesis of claim 3, wherein the outflow section has a circular cross-section.

6. The prosthesis of claim 3, wherein the outflow section is configured to expand within and support against a native valve annulus.

7. The prosthesis of claim 3, wherein the inflow section is flared outward from the outflow section.

8. The prosthesis of claim 1, wherein one of the engagement arms is self-expanding.

9. The prosthesis of claim 1, wherein the frame further comprises a second commissure post parallel to the longitudinal axis of the inner support structure.

10. The prosthesis of claim 9, wherein a second end of the first engagement arm is attached to the second commissure post and a second end of the second engagement arm is attached to the second commissure post.

11. The prosthesis of claim 1, wherein the inflow section is configured to expand within and support against an atrium.

12. The prosthesis of claim 1, wherein the frame further comprises fixation barbs attached to the inflow section.

13. A heart valve prosthesis comprising:

a frame comprising;

an inner support structure including an expandable inflow section having an asymmetrical shape and an expandable outflow section; and

an outer support structure coupled to the inner support structure, the outer support structure including first and second commissure posts and first and second engagement arms, wherein the first and second commissure posts are parallel to a longitudinal axis of the inner support structure, wherein a first end of the first engagement arm is attached to the first commissure post and a first end of the second engagement arm is attached to the first commissure post, wherein a second end of the first engagement arm is attached to the second commissure post and a second end of the second engagement arm is attached to the second commissure post; and

a valve structure attached to the frame within an interior area of the inner support structure.