Dialysis implant and methods of use

• US 10,398,824 B2
• Filed: 09/16/2015
• Issued: 09/03/2019
• Est. Priority Date: 08/18/2004
• Status: Active Grant

• Current Assignee: Sequana Medical NV
• Original Assignee: Sequana Medical NV
• Inventors: Burnett, Daniel R., Hall, Gregory W.
• Primary Examiner(s): Stigell, Theodore J
• Application Number:
  US14/856,447
• Publication Number:
  US 20160000984A1
• Time in Patent Office: 1,448 Days
• CPC Class Codes: A61M 1/1656 Apparatus for preparing dialysates
• CPC Class Codes: A61M 1/1668 Details of containers
• CPC Class Codes: A61M 1/1676 containing proteins, e.g. albumin
• CPC Class Codes: A61M 1/1678 intracorporal peritoneal dialysis A61M1/28
• CPC Class Codes: A61M 1/28 Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
• CPC Class Codes: A61M 1/282 Operational modes
• CPC Class Codes: A61M 1/285 Catheters therefor
• CPC Class Codes: A61M 2205/04 implanted
• CPC Class Codes: A61M 2230/005 Parameter used as control input for the apparatus

Abstract

A device and methods for treating renal failure are disclosed. One embodiment of the device is an implantable peritoneal dialysis device. When in use, the device can have a semi-permeable reservoir implanted in the peritoneal cavity. The reservoir can receive blood waste and drain through one or more conduits, via a pump, to the biological bladder. Solids and/or a solution benefiting dialysis can be pumped to the reservoir and/or implanted in the peritoneal cavity.

Claims

1. A fluid management system comprising:

an infusate comprising an osmotic agent for infusion into a peritoneal cavity;

a reservoir conduit adapted for introducing the infusate into the peritoneal cavity;

an implantable pump having an internal battery that is inductively chargeable, the implantable pump adapted for fluidic communication with the peritoneal cavity and a bladder;

a drainage conduit adapted for coupling between the peritoneal cavity and the implantable pump; and

an exit conduit adapted for coupling between the bladder and the implantable pump,

wherein the implantable pump is configured to pump a peritoneal fluid mixture from the peritoneal cavity through the drainage conduit into the bladder through the exit conduit, and

wherein the peritoneal fluid mixture comprises the infusate comprising the osmotic agent.

2. The system of claim 1, further comprising an implantable controller associated with the implantable pump.

3. The system of claim 2, wherein the implantable controller is configured to monitor a physiologic parameter, the implantable controller programmed to cause the implantable pump to pump the peritoneal fluid mixture from the peritoneal cavity to the bladder responsive to a value of the monitored physiologic parameter.

4. The system of claim 3, wherein the monitored physiological parameter comprises pressure, pH, temperature, electrolyte concentration, analyte concentration, or any combination thereof of the peritoneal cavity or the bladder or both.

5. The system of claim 2, wherein the implantable controller is configured to monitor a difference in pressure between the peritoneal cavity and the bladder.

6. The system of claim 1, further comprising a reservoir adapted for coupling to the implantable pump via the reservoir conduit,

wherein the implantable pump is configured to pump the infusate comprising the osmotic agent from the reservoir through the reservoir conduit into the peritoneal cavity through the drainage conduit to form the peritoneal fluid mixture in the peritoneal cavity.

7. The system of claim 6, further comprising an implantable controller associated with the implantable pump, the implantable controller configured to monitor a physiologic parameter, the implantable controller programmed to cause the implantable pump to pump the infusate from the reservoir to the peritoneal cavity responsive to a value of the monitored physiologic parameter.

8. The system of claim 7, wherein the monitored physiological parameter comprises pressure, pH, temperature, electrolyte concentration, analyte concentration, or any combination thereof of the peritoneal cavity or the bladder or both.

9. The system of claim 6, wherein the implantable pump is configured to pump the infusate comprising the osmotic agent from the reservoir through the reservoir conduit into the peritoneal cavity through the drainage conduit as a function of time.

10. The system of claim 6, wherein the reservoir is adapted for implantation.

11. The system of claim 1, wherein the implantable pump is configured to pump the peritoneal fluid mixture from the peritoneal cavity through the drainage conduit into the bladder through the exit conduit as a function of time.

12. The system of claim 1, further comprising an inductive recharging circuit for recharging the internal battery.

13. The system of claim 1, wherein the drainage conduit comprises a semi-permeable conduit.