Systems and methods for treating cardiac arrhythmias

• US 10,398,901 B2
• Filed: 05/18/2017
• Issued: 09/03/2019
• Est. Priority Date: 02/06/2015
• Status: Active Grant

• Current Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Original Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Inventors: Koop, Brendan E.
• Primary Examiner(s): Holmes, Rex R
• Application Number:
  US15/598,783
• Publication Number:
  US 20170252567A1
• Time in Patent Office: 838 Days
• CPC Class Codes: A61N 1/0573 chacterised by means penetrating the heart tissue, e.g. helix needle or hook
• CPC Class Codes: A61N 1/36514 controlled by a physiological quantity other than heart potential, e.g. blood pressure controlled by two or more physical parameters A61N1/36585
• CPC Class Codes: A61N 1/368 comprising more than one electrode co-operating with different heart regions A61N1/3622, A61N1/3627 take precedence
• CPC Class Codes: A61N 1/37205 Microstimulators, e.g. implantable through a cannula
• CPC Class Codes: A61N 1/37288 Communication to several implantable medical devices within one patient
• CPC Class Codes: A61N 1/3756 Casings with electrodes thereon, e.g. leadless stimulators
• CPC Class Codes: A61N 2001/0585 Coronary sinus electrodes

Abstract

An implantable medical device (IMD) may include a housing having a proximal end and a distal end and a set of one or more electrodes connected to but spaced apart from the housing. The IMD may further include a controller disposed within the housing, wherein the controller is configured to sense cardiac electrical signals, and deliver electrical stimulation pulses via the first set of one or more electrodes. In some embodiments, a first portion of the housing is configured to be disposed at least partly within a coronary sinus of a patient'"'"'s heart and a second portion of the housing is configured to be disposed at least partly within a right atrium of the patient'"'"'s heart.

Claims

1. An implantable medical device (IMD) comprising:

a body having a proximal end and a distal end, wherein the body is configured to be disposed at least partially within the coronary sinus of a patient'"'"'s heart;

an extension having a length and extending distally from the body, the extension configured to traverse down the great cardiac vein of the patient'"'"'s heart and along at least part of the left ventricle, the extension being more flexible than the body;

a first electrode supported by the extension distally of the body and positioned at a longitudinal location along the length of the extension so as to be adjacent the left atrium of the patient'"'"'s heart in order to sense one or more cardiac signals of the left atrium of the patient'"'"'s heart;

a second electrode supported by the extension distally from the body and positioned distally of the first electrode and at a longitudinal location along the length of the extension so as to be adjacent the left ventricle of the patient'"'"'s heart in order to deliver pacing pulses to the left ventricle of the patient'"'"'s heart;

a controller housed by the body and operatively coupled to the first electrode and the second electrode, the controller configured to detect a contraction of the left atrium based at least in part on one or more cardiac signals sensed using the first electrode, and in response to detecting a contraction of the left atrium, deliver a pacing pulse to the left ventricle using the second electrode;

a guide wire entrance port distal of the proximal end of the body; and

a guide wire exit port distal of the guide wire entrance port, wherein the IMD defines a guide wire lumen extending between the guide wire entrance port and the guide wire exit port such that a guidewire must pass alongside at least part of the body within the coronary sinus before entering the guide wire entrance port.

2. The IMD of claim 1, wherein the extension comprises two or more second electrodes each positioned distally of the body at a different longitudinal location along the length of the extension so as to be adjacent a different part of the left ventricle of the patient'"'"'s heart.

3. The IMD of claim 2, wherein the controller is configured to deliver the pacing pulse to the left ventricle using less than all of the two or more second electrodes.

4. The IMD of claim 1, wherein the extension comprises two or more first electrodes each positioned distally of the body at a different longitudinal location along the length of the extension so as to be adjacent a different part of the left atrium of the patient'"'"'s heart.

5. The IMD of claim 4, wherein the controller is configured to detect a contraction of the left atrium based at least in part on one or more cardiac signals sensed using less than all of the two or more first electrodes.

6. The IMD of claim 4, wherein the controller is configured to deliver a pacing pulse to the left atrium using less than all of the two or more first electrodes.

7. The IMD of claim 1, wherein the controller is configured to deliver a pacing pulse to the left ventricle a predetermined time delay after the controller detects a contraction of the left atrium.

8. The IMD of claim 7, wherein the controller is configured to determine a heart rate of the patient, and wherein the predetermined time delay is dependent on the determined heart rate of the patient.

9. The IMD of claim 1, wherein the extension is pre-biased into a non-linear shape.

10. The IMD of claim 1, wherein the extension comprises a fixation mechanism for securing the extension in the great cardiac vein.

11. The IMD of claim 1, wherein the body has a length, and wherein the length of the extension is between 2 and 10 times longer than the length of the body.

12. The IMD of claim 1, further comprising a communications module coupled to the controller, wherein the communications module is configured to support communication with one or more remote devices.

13. The IMD of claim 1, wherein the extension and body are modular such that a physician can select a particular extension from a set of different extensions and connect the selected extension to the body before implantation of the IMD.

14. An implantable medical device (IMD) comprising:

a body having a proximal end and a distal end, wherein the body is configured to be disposed at least partially within the coronary sinus of a patient'"'"'s heart;

an extension having a length and extending distally from the body, the extension is configured to traverse down the great cardiac vein of the patient'"'"'s heart and along at least part of the left ventricle, the extension being more flexible than the body;

one or more first electrodes supported by the extension distally of the body and each positioned at a longitudinal location along the length of the extension so as to be adjacent the left atrium of the patient'"'"'s heart in order to sense one or more cardiac signals of the left atrium of the patient'"'"'s heart;

two or more second electrodes supported by the extension distally of the body and positioned distally of the first electrode and at spaced longitudinal locations along the length of the extension so as to be adjacent different parts of the left ventricle of the patient'"'"'s heart in order to deliver pacing pulses to the left ventricle of the patient'"'"'s heart;

a controller housed by the body and operatively coupled to the first electrode and the second electrode, the controller configured to detect a contraction of the left atrium based at least in part on one or more cardiac signals sensed using one or more of the first electrodes, and in response to detecting a contraction of the left atrium, deliver a pacing pulse to the left ventricle using one or more of the second electrodes a predetermined time delay after the controller detects the contraction of the left atrium;

the controller further configured to deliver a pacing pulse to the left atrium using one or more of the first electrodes when needed;

a guide wire entrance port distal of the proximal end of the body; and

a guide wire exit port distal of the guide wire entrance port, wherein the IMD defines a guide wire lumen extending between the guide wire entrance port and the guide wire exit port such that a guidewire must pass alongside at least part of the body within the coronary sinus before entering the guide wire entrance port.

15. The IMD of claim 14, wherein the controller is configured to deliver the pacing pulse to the left ventricle using less than all of the two or more second electrodes.

16. The IMD of claim 14, wherein the extension is pre-biased into a non-linear shape.

17. The IMD of claim 14, wherein the extension comprises a fixation mechanism for securing the extension in the great cardiac vein.

18. An implantable medical device (IMD) comprising:

a body having a proximal end and a distal end, wherein the body is configured to be disposed at least partially within the coronary sinus of a patient'"'"'s heart;

an extension having a length and extending distally from the body to a distal end, the extension is configured to traverse down the great cardiac vein of the patient'"'"'s heart and along at least part of the left ventricle, the extension being more flexible than the body;

one or more electrodes supported by the extension distally of the body;

a controller housed by the body and operatively coupled to the one or more electrodes;

a power source housed by the body for providing power to the controller;

a guide wire entrance port distal of the proximal end of the body; and

a guide wire exit port distal of the guide wire entrance port, wherein the IMD defines a guide wire lumen extending between the guide wire entrance port and the guide wire exit port such that a guidewire must pass alongside at least part of the body within the coronary sinus before entering the guide wire entrance port.

19. The IMD of claim 18, wherein the guide wire entrance port is distal of the power source housed by the body and proximal of the distal end of the extension.

20. The IMD of claim 18, wherein the guide wire exit port is proximate the distal end of the extension.