Analyte sensing for eye injuries and conditions
First Claim
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1. A biosensor for the detection of an analyte, the biosensor comprising:
- a layer comprising a mixture of graphene nanoplatelets and one or more polymers, wherein the polymers are amphiphilic block copolymers, a layer of a ligand for the analyte in contact with hydrophilic blocks of the amphiphilic block copolymers;
at least one sensor electrode; and
a substrate.
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Abstract
A biosensor for the detection of an analyte such as ascorbic acid is provided. Also provided is a device comprising the biosensor. In addition, methods of detecting analytes such as ascorbic acid in a sample, and methods of a point-of-care diagnosis of eye disease and eye injury are provided.
13 Citations
20 Claims
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1. A biosensor for the detection of an analyte, the biosensor comprising:
- a layer comprising a mixture of graphene nanoplatelets and one or more polymers, wherein the polymers are amphiphilic block copolymers, a layer of a ligand for the analyte in contact with hydrophilic blocks of the amphiphilic block copolymers;
at least one sensor electrode; and
a substrate. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16)
- a layer comprising a mixture of graphene nanoplatelets and one or more polymers, wherein the polymers are amphiphilic block copolymers, a layer of a ligand for the analyte in contact with hydrophilic blocks of the amphiphilic block copolymers;
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17. A device comprising a biosensor comprising a layer comprising a mixture of graphene nanoplatelets and one or more polymers, wherein the polymers are amphiphilic block copolymers, a layer of a ligand for an analyte in contact with hydrophilic blocks of the amphiphilic block copolymers;
- at least one sensor electrode;
a substrate; and
a detector connected to a data acquisition system. - View Dependent Claims (18, 19, 20)
- at least one sensor electrode;
Specification