Sample analyzer and computer program product
DC CAFCFirst Claim
1. A sample analyzer comprising:
- a plurality of detectors each configured to sense cells in a sample, the sample selectively comprising (i) a blood sample or (ii) a body fluid sample, wherein the body fluid sample contains body fluid, other than blood, which is selected from a group consisting of cerebrospinal fluid, thoracic fluid, abdominal fluid, fluid collected in a cardiac sac, synovial fluid, dialysate from peritoneal dialysis, and intraperitoneal rinse;
a controller programmed to selectively operate the sample analyzer in a blood measuring mode or a body fluid measuring mode, wherein the blood measuring mode includes a sequence of operations for measuring cells in the blood sample, and the body fluid measuring mode includes a sequence of operations for measuring cells in the body fluid sample, and wherein a respective sequence of operations for measuring cells in the blood sample and in the body fluid sample comprises (a) a sensing operation comprising operations of preparing for measurement and operating a detector to sense cells in the sample and (b) an analyzing operation comprising operations of analyzing sample measurements from the sensing operation and displaying analysis results, the sensing operation performed in the body fluid measuring mode being different, at least partially, from the sensing operation performed in the blood measuring mode, and further wherein the plurality of detectors include one or more multi-mode detectors configured to operate in both the blood measuring mode and the body fluid measuring mode,the controller programmed to;
display on an input screen (1) at least two sample-type options that comprise concurrent display of a blood sample option and a body fluid sample option each independently selectable from the other on the input screen and (2) one or more test modes displayed separately from a selected one of the at least two sample-type options, wherein selecting the body fluid sample option from the at least two sample-type options and setting a test mode from the one or more test modes is based on repective discrete user inputs separately received in the input screen;
in response to (I) a user input, on the input screen, of selecting the blood sample option from the displayed at least two sample-type options and (II) an additional user input, on the input screen, of setting one test mode from the displayed one or more test modes, perform the sensing operation in the blood measuring mode to;
prepare a blood measurement sample from the blood sample;
introduce at least part of the prepared blood measurement sample into a multi-mode detector; and
operate said multi-mode detector to sense cells in the introduced blood measurement sample, and further perform the analyzing operation in the blood measuring mode to;
analyze blood-sample measurements of cells sensed in the introduced blood measurement sample; and
display analysis results of the blood-sample measurements on a first test result screen; and
in response to (I) a user input, on the input screen, of selecting the body fluid sample option from the displayed at least two test-sample options and (II) an additional user input, on the input screen, of setting said one or a different test mode from the displayed one or more test modes, perform the sensing operation in the body fluid measuring mode to;
prepare a body fluid measurement sample from the body fluid sample;
introduce at least part of the prepared body fluid measurement sample into said multi-mode detector; and
operate said multi-mode detector to sense cells in the introduced body fluid measurement sample, and further perform the analyzing operation in the body fluid measuring mode to;
analyze body-fluid-sample measurements of the cells sensed in the introduced body fluid measurement sample; and
display analysis results of the body-fluid-sample measurements on a second test result screen.
1 Assignment
Litigations
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Accused Products
Abstract
A sample analyzer prepares a measurement sample from a blood sample or a body fluid sample which differs from the blood sample; measures the prepared measurement sample; obtains characteristic information representing characteristics of the components in the measurement sample; sets either a blood measurement mode for measuring the blood sample, or a body fluid measurement mode for measuring the body fluid sample as an operating mode; and measures the measurement sample prepared from the blood sample by executing operations in the blood measurement mode when the blood measurement mode has been set, and measuring the measurement sample prepared from the body fluid sample by executing operations in the body fluid measurement mode that differs from the operations in the blood measurement mode when the body fluid measurement mode has been set, is disclosed. A computer program product is also disclosed.
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Citations
29 Claims
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1. A sample analyzer comprising:
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a plurality of detectors each configured to sense cells in a sample, the sample selectively comprising (i) a blood sample or (ii) a body fluid sample, wherein the body fluid sample contains body fluid, other than blood, which is selected from a group consisting of cerebrospinal fluid, thoracic fluid, abdominal fluid, fluid collected in a cardiac sac, synovial fluid, dialysate from peritoneal dialysis, and intraperitoneal rinse; a controller programmed to selectively operate the sample analyzer in a blood measuring mode or a body fluid measuring mode, wherein the blood measuring mode includes a sequence of operations for measuring cells in the blood sample, and the body fluid measuring mode includes a sequence of operations for measuring cells in the body fluid sample, and wherein a respective sequence of operations for measuring cells in the blood sample and in the body fluid sample comprises (a) a sensing operation comprising operations of preparing for measurement and operating a detector to sense cells in the sample and (b) an analyzing operation comprising operations of analyzing sample measurements from the sensing operation and displaying analysis results, the sensing operation performed in the body fluid measuring mode being different, at least partially, from the sensing operation performed in the blood measuring mode, and further wherein the plurality of detectors include one or more multi-mode detectors configured to operate in both the blood measuring mode and the body fluid measuring mode, the controller programmed to; display on an input screen (1) at least two sample-type options that comprise concurrent display of a blood sample option and a body fluid sample option each independently selectable from the other on the input screen and (2) one or more test modes displayed separately from a selected one of the at least two sample-type options, wherein selecting the body fluid sample option from the at least two sample-type options and setting a test mode from the one or more test modes is based on repective discrete user inputs separately received in the input screen; in response to (I) a user input, on the input screen, of selecting the blood sample option from the displayed at least two sample-type options and (II) an additional user input, on the input screen, of setting one test mode from the displayed one or more test modes, perform the sensing operation in the blood measuring mode to;
prepare a blood measurement sample from the blood sample;
introduce at least part of the prepared blood measurement sample into a multi-mode detector; and
operate said multi-mode detector to sense cells in the introduced blood measurement sample, and further perform the analyzing operation in the blood measuring mode to;
analyze blood-sample measurements of cells sensed in the introduced blood measurement sample; and
display analysis results of the blood-sample measurements on a first test result screen; andin response to (I) a user input, on the input screen, of selecting the body fluid sample option from the displayed at least two test-sample options and (II) an additional user input, on the input screen, of setting said one or a different test mode from the displayed one or more test modes, perform the sensing operation in the body fluid measuring mode to;
prepare a body fluid measurement sample from the body fluid sample;
introduce at least part of the prepared body fluid measurement sample into said multi-mode detector; and
operate said multi-mode detector to sense cells in the introduced body fluid measurement sample, and further perform the analyzing operation in the body fluid measuring mode to;
analyze body-fluid-sample measurements of the cells sensed in the introduced body fluid measurement sample; and
display analysis results of the body-fluid-sample measurements on a second test result screen. - View Dependent Claims (2, 3, 4, 5, 6, 29)
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7. A sample analyzer comprising:
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a plurality of detectors comprising at least one optical detector for optically sensing cells in a sample and at least one electrical detector for electrically sensing cells in the sample, the sample selectively comprising (i) a blood sample or (ii) a body fluid sample, wherein the body fluid sample contains body fluid, other than blood, which is selected from a group consisting of cerebrospinal fluid, thoracic fluid, abdominal fluid, fluid collected in a cardiac sac, synovial fluid, dialysate from peritoneal dialysis, and intraperitoneal rinse; a controller programmed to selectively operate the sample analyzer in a blood measuring mode or a body fluid measuring mode, wherein the blood measuring mode includes a sequence of operations for measuring cells in the blood sample, and the body fluid measuring mode includes a sequence of operations for measuring cells in the body fluid sample, and wherein a respective sequence of operations for measuring cells in the blood sample and in the body fluid sample comprises (a) a sensing operation comprising operations of preparing for measurement and operating a detecter to sense cells in the sample and (b) an analyzing operation comprising operations of analyzing measurements from the sensing operation and displaying analysis results, and further wherein the plurality of detectors include one or more multi-mode detectors configured to operate in both the blood measuring mode and the body fluid measuring mode, the controller programmed to; display on an input screen (1) at least two sample-type options that comprise concurrent display of a blood sample option and a body fluid sample option each independently selectable from the other on the input screen and (2) one or more test modes displayed separately from a selected one of the at least two sample-type options; in response to (I) a user input, on the input screen, of selecting the blood sample option from the displayed at least two sample-type options and (II) an additional user input, on the input screen, of setting one test mode from the displayed one or more test modes, perform the sensing operation in the blood measuring mode to;
prepare a blood measurement sample from the blood sample;
introduce at least part of the prepared blood measurement sample into an optical detector; and
operate the optical detector to optically sense white blood cells in the introduced blood measurement sample, and further perform the analyzing operation in the blood measuring mode to;
analyze blood-sample measurements of the white blood cells sensed in the introduced blood measurement sample;
count each of five types of white blood cells based on the analyzed blood-sample measurements; and
display a count of each of the five types of white blood cells; andin response to (I) a user input, on the input screen, of selecting the body fluid sample option from the displayed at least two sample-type options and (II) an additional user input, on the input screen, of setting said one or a different test mode from the displayed one or more test modes, perform the sensing operation in the body fluid measuring mode to;
prepare a body fluid measurement sample from the body fluid sample;
introduce at least part of the prepared body fluid measurement sample into an electrical detector;
operate said electrical detector to electrically sense cells in the introduced body fluid measurement sample, and further perform the analyzing operation in the body fluid measuring mode to;
analyze body-fluid-sample measurements of cells sensed in the introduced body fluid measurement sample;
count mono-nucleated cells and poly-nucleated cells based on the analyzed body-fluid-sample measurements; and
separately display in a screen a count of the mono-nucleated cells and a count of the poly-nucleated cells. - View Dependent Claims (8, 9, 10, 11, 12, 13, 14, 15)
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16. A sample analyzer comprising:
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a plurality of detectors each configured to sense cells in a sample, the sample selectively comprising (i) a blood sample or (ii) a body fluid sample, wherein the body fluid sample contains body fluid, other than blood, which is selected from a group consisting of cerebrospinal fluid, thoracic fluid, abdominal fluid, fluid collected in a cardiac sac, synovial fluid, dialysate from peritoneal dialysis, and intraperitoneal rinse; a controller programmed to selectively operate the sample analyzer in a blood measuring mode or a body fluid measuring mode, wherein the blood measuring mode includes a sequence of operations for measuring cells in the blood sample, and the body fluid measuring mode includes a sequence of operations for measuring cells in the body fluid sample, and wherein a respective sequence of operations for measuring cells in the blood sample and in the body fluid sample comprises a sensing operation comprising operations of preparing for measurement and operating a detector to sense cells in the sample, and further wherein the plurality of detectors include one or more multi-mode detectors configured to operate in both the blood measuring mode and the body fluid measuring mode, the controller programmed to; display on an input screen (1) at least two sample-type options that comprise concurrent display of a blood sample option and a body fluid sample option each independently selectable from the other on the input screen, and (2) one or more test modes displayed separately from a selected one of the at least two sample type options, wherein selecting the body fluid sample option from the at least two sample-type options and setting a test mode from the one or more test modes is based on respective discrete user inputs separately received in the input screen; in response to (I) a user input, on the input screen, of selecting the blood sample option from the displayed at least two sample-type options and (II) an additional user input, on the input screen, of setting one test mode from the displayed one or more test modes, perform the sensing operation in the blood measuring mode to;
prepare a blood measurement sample from the blood sample;
introduce at least part of the prepared blood measurement sample into a multi-mode detector; and
operate said multi-mode detector to sense cells in the introduced blood measurement sample; andin response to (I) a user input, of selecting the body fluid sample option from the displayed at least two sample-type options and (II) an additional user input, on the input screen, of setting said one or a different test mode from the displayed one or more test modes, perform the sensing operation in the body fluid measuring mode to;
prepare a body fluid measurement sample from the body fluid sample;
introduce at least part of the prepared body fluid measurement sample into said multi-mode detector; and
operate said multi-mode detector to sense cells in the introduced body fluid measurement sample,wherein the sensing operation performed in the body fluid measuring mode comprises an operation of pre-washing said multi-mode detector to reduce a carryover effect on measurements of the body fluid measurement sample, wherein the controller is programmed to automatically initiate said pre-washing, during said sensing operation in the body fluid measuring mode before introduction of the body fluid measurement sample into said multi-mode detector, and the controller is programmed not to introduce the prepared body fluid measurement sample into said multi-mode detector before said pre-washing is completed. - View Dependent Claims (17, 18, 19, 20, 21, 22, 23)
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24. A sample analyzer comprising:
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a plurality of detectors each configured to sense cells in a sample, the sample selectively comprising (i) a blood sample or (ii) a body fluid sample, wherein the body fluid sample contains body fluid, other than blood, which is selected from a group consisting of cerebrospinal fluid, thoracic fluid, abdominal fluid, fluid collected in a cardiac sac, synovial fluid, dialysate from peritoneal dialysis, and intraperitoneal rinse; a controller programmed to selectively operate the sample analyzer in a blood measuring mode or a body fluid measuring mode, wherein the blood measuring mode includes a sequence of operations for measuring cells in the blood sample, and the body fluid measuring mode includes a sequence of operations for measuring blood cells in the body fluid sample, and wherein a respective sequence of operations for measuring blood cells in the blood sample and in the body fluid sample comprises (a) a sensing operation comprising operations of preparing for measurement and operating a detector to sense cells in the sample, and (b) an analyzing operation comprising operations of analyzing sample measurements from the sensing operation and displaying analysis results, and further wherein the plurality of detectors include one or more multi-mode detectors configured to operate in both the blood measuring mode and the body fluid measuring mode, the controller programmed to; display on an input screen (1) at least two sample-type options that comprise concurrent display of a blood sample option and a body fluid sample option each selectable independently from the other on the input screen and (2) one or more test modes displayed separately from a selected one of the at least two sample-type options, in response to (I) a user input, on the input screen, of selecting the body fluid sample option from the displayed at least two sample-type options and (II) an additional user input, on the input screen, of setting one test mode from the displayed one or more test modes, (A) perform the sensing operation in the body fluid measuring mode to;
prepare a first body fluid measurement sample from the body fluid sample; and
sense cells in the first body fluid measurement sample, and further perform the analyzing operation in the body fluid measuring mode to;
analyze first measurements of the cells sensed in the first body fluid measurement sample and count red blood cells based on the analyzed first measurements, and(B) perform the sensing operation in the body fluid measuring mode to;
prepare a second body fluid measurement sample from the body fluid sample; and
sense cells in the second body fluid measurement sample, and further perform the analyzing operation in the body fluid measuring mode to;
analyze second measurements of the cells sensed in the second body fluid measurement sample; and
count mono-nucleated cells and poly-nucleated cells based on the analyzed second measurements, wherein the controller is programmed to separately display in a screen a count of the red blood cells, a count of the mono-nucleated cells and a count of the poly-nucleated cells. - View Dependent Claims (25, 26, 27, 28)
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Specification