Dual chamber inhaler for sequentially administering multiple drugs
First Claim
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1. A portable medical device for sequential aerosolized administration of at least two pharmaceutical agents, the device comprising:
- a first chamber configured to have a first sprayable active formulation disposed therein, the first sprayable active formulation comprising a first pharmaceutical agent;
a second chamber configured to have a second sprayable active formulation disposed therein, the second sprayable active formulation comprising a second pharmaceutical agent having an effect of countering, enhancing, or mitigating an effect of the first pharmaceutical agent;
a dispensing nozzle configured to permit an initial administration of the first sprayable active formulation, the dispensing nozzle further configured to permit one or more subsequent administrations of the second sprayable active formulation through a bodily tissue; and
a valve chamber in communication with the first chamber, the second chamber, and the dispensing, nozzle, the valve chamber having a valve member configured to move between a first position where the valve member only permits communication between the first chamber and the dispensing nozzle, and a second position where the valve member only permits communication between the second chamber and the dispensing nozzle.
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Abstract
Devices and methods for sequential aerosolized administration of pharmaceutical agents. A portable device may be used to administer an initial dose of an active formulation comprising at least one first pharmaceutical agent and a subsequent dose of an active formulation comprising at least one second pharmaceutical agent that may have the effect of countering, enhancing, or mitigating the first pharmaceutical agent.
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Citations
22 Claims
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1. A portable medical device for sequential aerosolized administration of at least two pharmaceutical agents, the device comprising:
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a first chamber configured to have a first sprayable active formulation disposed therein, the first sprayable active formulation comprising a first pharmaceutical agent; a second chamber configured to have a second sprayable active formulation disposed therein, the second sprayable active formulation comprising a second pharmaceutical agent having an effect of countering, enhancing, or mitigating an effect of the first pharmaceutical agent; a dispensing nozzle configured to permit an initial administration of the first sprayable active formulation, the dispensing nozzle further configured to permit one or more subsequent administrations of the second sprayable active formulation through a bodily tissue; and a valve chamber in communication with the first chamber, the second chamber, and the dispensing, nozzle, the valve chamber having a valve member configured to move between a first position where the valve member only permits communication between the first chamber and the dispensing nozzle, and a second position where the valve member only permits communication between the second chamber and the dispensing nozzle. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19)
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20. A method for sequential aerosolized administration of at least two pharmaceutical agents for the treatment of pain, the method comprising:
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selecting a portable device for sequential aerosolized administration of at least two pharmaceutical agents for the treatment of pain, the device comprising a first chamber having a first sprayable formulation disposed therein, a second chamber having a second sprayable formulation disposed therein, a dispensing nozzle configured to permit administration of the first sprayable formulation and the second sprayable formulation, and a valve chamber in communication with the first chamber, the second chamber, and the dispensing nozzle, the valve chamber having a valve member configured to permit communication between the first chamber or the second chamber, and the dispensing nozzle; administering an initial dose of the first sprayable active formulation alone through a bodily tissue of a patient, the first sprayable active formulation comprising a first pharmaceutical agent; and administering a subsequent dose of the second sprayable active formulation alone through the bodily tissue of the patient, the second sprayable active formulation comprising a second pharmaceutical agent having an effect of countering, enhancing, or mitigating an effect of the first pharmaceutical agent; wherein the first and second sprayable active formulations are not co-administered simultaneously. - View Dependent Claims (21, 22)
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Specification