Methods and systems for intraventricular brain stimulation
First Claim
1. A neuromodulation system configured to pass into, within, or through brain tissue from a lateral entry site to provide bilateral deep brain stimulation, the system comprising:
- an electrode catheter comprising one or more passageways for fluid, wherein the electrode catheter comprises at least one fluid drainage perforation that is configured to drain fluid through the one or more passageways, wherein the electrode catheter is configured to provide both electrical and drainage capabilities; and
a plurality of electrodes or effectors carried by the electrode catheter configured for bilateral stimulation and configured to modulate neural activity thereby modulating a neural state, wherein the at least one fluid drainage perforation is located between the plurality of electrodes or effectors;
wherein the electrode catheter is sized and configured to pass through one lateral ventricle in a unilateral approach through a foramen of Monroe on an ipsilateral side into the third ventricle, and a tip of the electrode catheter is configured to curve under the ipsilateral fornix to the contralateral fornix by curving from the foramen of Monroe on the ipsilateral side past the ipsilateral fornix to the contralateral fornix.
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Abstract
The present application is directed to devices and methods that can treat dementia or other brain disorders via electrical stimulation. Embodiments disclosed herein utilize brain stimulation of brain areas involved in memory and cognition through an intraventricular approach. Brain stimulation is combined with CSF flow in an intraventricular electrode having one or more passageways to permit fluid to flow therethrough. For example, an intraventricular electrode shunt catheter can be safely placed in any part of the ventricular system and through any foramen or aqueduct of the ventricular system without fear of obstruction to CSF flow.
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Citations
20 Claims
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1. A neuromodulation system configured to pass into, within, or through brain tissue from a lateral entry site to provide bilateral deep brain stimulation, the system comprising:
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an electrode catheter comprising one or more passageways for fluid, wherein the electrode catheter comprises at least one fluid drainage perforation that is configured to drain fluid through the one or more passageways, wherein the electrode catheter is configured to provide both electrical and drainage capabilities; and a plurality of electrodes or effectors carried by the electrode catheter configured for bilateral stimulation and configured to modulate neural activity thereby modulating a neural state, wherein the at least one fluid drainage perforation is located between the plurality of electrodes or effectors; wherein the electrode catheter is sized and configured to pass through one lateral ventricle in a unilateral approach through a foramen of Monroe on an ipsilateral side into the third ventricle, and a tip of the electrode catheter is configured to curve under the ipsilateral fornix to the contralateral fornix by curving from the foramen of Monroe on the ipsilateral side past the ipsilateral fornix to the contralateral fornix. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20)
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Specification