Integrated cartridge housings for sample analysis
First Claim
1. A method of making a test cartridge for measuring an analyte or property of a liquid sample, the method comprising the steps of:
- (a) molding a housing comprising;
(i) a top portion including a first substantially rigid zone and a substantially flexible zone, and (ii) a bottom portion including a second substantially rigid zone, wherein the second substantially rigid zone comprises one or more sensor recesses;
(b) inserting a sensor into at least one of the one or more sensor recesses;
(c) abutting the top portion with the bottom portion; and
(d) sealing the housing in a closed position, wherein the sealing forms the test cartridge, and the test cartridge comprises a conduit, formed by the top portion and the bottom portion of the housing, over at least a portion of the sensor.
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Accused Products
Abstract
The invention relates to a cartridge housing for forming a cartridge capable of measuring an analyte or property of a liquid sample. The housing including a top portion having a first substantially rigid zone and a substantially flexible zone, a bottom portion separate from the top portion including a second substantially rigid zone, and at least one sensor recess containing a sensor. The top portion and the bottom portion are bonded to form the cartridge having a conduit over at least a portion of the sensor. The invention also relates to methods for forming such cartridges and to various features of such cartridges.
30 Citations
32 Claims
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1. A method of making a test cartridge for measuring an analyte or property of a liquid sample, the method comprising the steps of:
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(a) molding a housing comprising;
(i) a top portion including a first substantially rigid zone and a substantially flexible zone, and (ii) a bottom portion including a second substantially rigid zone, wherein the second substantially rigid zone comprises one or more sensor recesses;(b) inserting a sensor into at least one of the one or more sensor recesses; (c) abutting the top portion with the bottom portion; and (d) sealing the housing in a closed position, wherein the sealing forms the test cartridge, and the test cartridge comprises a conduit, formed by the top portion and the bottom portion of the housing, over at least a portion of the sensor. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23)
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24. A method for forming a cartridge, comprising:
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(a) providing a molded housing having two separate portions, at least one of which comprises a substantially rigid zone and a substantially flexible zone; (b) providing a gasket between the two separate portions; and (c) bonding the two portions using the gasket to form a fluid channel, wherein at least a portion of the gasket forms a channel seal. - View Dependent Claims (25, 26, 27, 28, 29, 30, 31, 32)
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Specification