Asymmetric ureas and medical uses thereof
First Claim
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1. 3-((S)-1-(2,3 -dichloro-4-methoxyphenyl)ethyl)-1-methyl-1-(1,3,3-trimethylpiperidin-4-yl)urea (GA202), or a pharmaceutically acceptable salt thereof.
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Abstract
Disclosed are compounds, compositions and methods for the prevention and/or treatment of diseases which are pathophysiologically mediated by the ghrelin receptor. The compounds have the general formula (I):
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Citations
3 Claims
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1. 3-((S)-1-(2,3 -dichloro-4-methoxyphenyl)ethyl)-1-methyl-1-(1,3,3-trimethylpiperidin-4-yl)urea (GA202), or a pharmaceutically acceptable salt thereof.
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2. (S)-1-hydroxy-3-(1-(4-methoxynaphthalen-1-yl)ethyl)-1-(1-methylpiperidin-4-yl)urea (GA170), or a pharmaceutically acceptable salt thereof.
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3. (S)-3-(1-(2,3-dichloro-4-methoxyphenyl)ethyl)-1-hydroxy-1-(1-methylpiperidin-4-yl)urea (GA182), or a pharmaceutically acceptable salt thereof.
Specification