Systems and methods for improved performance of fluidic and microfluidic systems
First Claim
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1. A microfluidic system, comprising:
- a microfluidic device having a first microchannel;
a fluid reservoir comprising a working fluid and being disposed outside of the microfluidic device;
a fluid line coupled to the fluid reservoir for delivering the working fluid to or from the microfluidic device; and
a fluid-resistance element removably coupled to the microfluidic device,the fluid-resistance element having a first fluidic resistance that is about 10-50,000 times greater than a second fluidic resistance associated with the microfluidic device, and wherein said fluid-resistance element comprises a substrate having an elongated fluid path.
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Abstract
Systems and methods for improved flow properties in fluidic and microfluidic systems are disclosed. The system includes a microfluidic device having a first microchannel, a fluid reservoir having a working fluid and a pressurized gas, a pump in communication with the fluid reservoir to maintain a desired pressure of the pressurized gas, and a fluid-resistance element located within a fluid path between the fluid reservoir and the first microchannel. The fluid-resistance element includes a first fluidic resistance that is substantially larger than a second fluidic resistance associated with the first microchannel.
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Citations
17 Claims
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1. A microfluidic system, comprising:
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a microfluidic device having a first microchannel; a fluid reservoir comprising a working fluid and being disposed outside of the microfluidic device; a fluid line coupled to the fluid reservoir for delivering the working fluid to or from the microfluidic device; and a fluid-resistance element removably coupled to the microfluidic device, the fluid-resistance element having a first fluidic resistance that is about 10-50,000 times greater than a second fluidic resistance associated with the microfluidic device, and wherein said fluid-resistance element comprises a substrate having an elongated fluid path. - View Dependent Claims (2, 3, 4, 5, 10, 11, 12, 13, 14)
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6. A microfluidic system, comprising:
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a cartridge comprising a fluid-resistance element, the cartridge configured to removably receive a microfluidic device having a first microchannel, the fluid-resistance element having a first fluidic resistance that is about 10-50,000 times greater than a second fluidic resistance associated with the microfluidic device, and wherein said fluid-resistance element comprises a substrate having an elongated fluid path; a fluid reservoir having a working fluid and a pressurized gas and being disposed outside of the microfluidic device; a pump in communication with the fluid reservoir to maintain a desired pressure of the pressurized gas; and a fluid path disposed between the fluid reservoir and the first microchannel. - View Dependent Claims (7, 8, 9, 15)
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16. A microfluidic system, comprising:
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a cartridge comprising a fluid-resistance element, the cartridge configured to removably receive a microfluidic device having a first microchannel, the fluid-resistance element having a first fluidic resistance that is at least about 10 times greater than a second fluidic resistance associated with the microfluidic device, and wherein said fluid-resistance element comprises a substrate having an elongated fluid path; a fluid reservoir having a working fluid and a pressurized gas and being disposed outside of the microfluidic device; a pump in communication with the fluid reservoir to maintain a desired pressure of the pressurized gas; and a fluid path disposed between the fluid reservoir and the first microchannel. - View Dependent Claims (17)
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Specification