Optical coherence tomography with a fizeau-type interferometer

• US 10,408,600 B2
• Filed: 06/22/2017
• Issued: 09/10/2019
• Est. Priority Date: 06/22/2017
• Status: Active Grant

• Current Assignee: Santec Holdings Corp.
• Original Assignee: Santec Incorporated
• Inventors: Chong, Changho
• Primary Examiner(s): Hansen, Jonathan M
• Application Number:
  US15/630,654
• Publication Number:
  US 20180372478A1
• Time in Patent Office: 810 Days
• CPC Class Codes: G01B 11/2441 using interferometry
• CPC Class Codes: G01B 9/02002 using two or more frequencies
• CPC Class Codes: G01B 9/02025 Interference between three or more discrete surfaces
• CPC Class Codes: G01B 9/02057 by using common path configuration, i.e. reference and object path almost entirely overlapping
• CPC Class Codes: G01B 9/02091 Tomographic interferometers, e.g. based on optical coherence
• CPC Class Codes: G01N 21/4795 spatially resolved investigating of object in scattering medium in vivo A61B

Abstract

An OCT system includes a light source configured to generate an optical beam, a Fizeau-type interferometer configured to receive the optical beam and produce an interference pattern, a detector configured to receive the interference pattern and produce an image signal, and a processing circuit including a processor and a memory, the memory being structured to store instructions that are executable by the processor to cause the processor to receive the image signal from the detector and generate an OCT image based on the image signal. The Fizeau-type interferometer includes a scanning element configured to receive the optical beam and direct the optical beam in a plurality of directions towards a sample and a reflective element configured to divide the directed optical beam into a reference beam and a sample beam that reflects off of a surface of a sample.

Claims

1. An optical system for generating an optical coherence tomography (OCT) image of a sample, the optical system comprising:

a light source configured to generate and project an optical beam along an optical path;

a scanning element configured to receive the optical beam and direct the optical beam in a plurality of directions towards the sample;

a first lens disposed between the scanning element and the sample, wherein the scanning element is disposed in a rear focal plane of the first lens to enable telecentric scanning of the sample by varying an orientation of the scanning element;

a reflective element disposed between the first lens and the sample, wherein the reflective element has a reflectivity within a range such that a first portion of the optical beam is transmitted through the reflective element to form a sample component beam and a second portion of the optical beam is reflected off of a surface of the reflective element to form a reference beam; and

a detector configured to receive an interference signal generated by the sample beam and the reference beam.

2. The optical system of claim 1, further comprising a second lens disposed between the light source and the scanning element, wherein the second lens is configured to collimate the optical beam prior to the optical beam reaching the scanning element.

3. The optical system of claim 1, further comprising an optical element configured to guide the interference signal to the detector.

4. The optical system of claim 3, wherein the optical element is also configured to receive the optical beam upon emission of the optical beam from the light source to direct the optical beam down the optical path.

5. The optical system of claim 4, further comprising a first optical fiber configured to guide the optical beam to the optical element and a second optical fiber configured to guide the optical beam to the second lens from the optical element.

6. The optical system of claim 5, wherein the optical element comprises a fiber circulator including a first port configured to receive the optical beam emitted by the light source, a second port configured to direct light received from the first port down the second optical fiber, and a third port configured to direct the reference beam and the sample beams down a third optical fiber to the detector.

7. The optical system of claim 1, wherein the surface of the reflective element is planar.

8. The optical system of claim 1, wherein the light source is a swept laser source having a coherence length of 10 mm or larger.

9. An OCT system comprising:

a light source configured to generate an optical beam;

a single-armed interferometer configured to receive the optical beam and produce an interference pattern, the single-armed interferometer comprising;

a scanning element configured to receive the optical beam and direct the optical beam in a plurality of directions towards a sample;

a first lens, wherein the scanning element is disposed in a rear focal plane of the first lens to enable telecentric scanning of the sample by varying an orientation of the scanning element; and

a reflective element configured to divide the directed optical beam into a reference component beam and a sample component beam that reflects off of a sample;

a detector configured to receive the interference pattern and produce an image signal; and

a processing circuit including a processor and a memory, the memory being structured to store instructions that are executable by the processor to cause the processor to receive the image signal from the detector and generate an OCT image based on the image signal.

10. The OCT system of claim 9, wherein the single-armed interferometer includes optical fibers and a second lens, wherein the optical fibers are configured to direct the optical beam to the second lens, wherein the second lens is configured to collimate the optical beam as it emerges from the optical fibers.

11. The OCT system of claim 10, wherein the scanning element is disposed between the first lens and the second lens, and wherein the first lens is configured to direct the sample component beam onto the surface of the sample.

12. The OCT system of claim 9, wherein a surface of the reflective element is planar.

13. The OCT system of claim 9, wherein the OCT image is generated using the Fourier domain method.

14. The OCT system of claim 9, wherein the light source is a swept laser source having a coherence length of 10 mm or larger.

15. A method of using an OCT system comprising:

emitting an optical beam from a light source;

guiding, by an optical fiber, the optical beam along an optical path to a combined arm of a Fizeau-type interferometer;

directing, by a scanner, the optical beam in one of a plurality of different directions after emission of the optical beam from the optical fiber;

orienting, by a first lens, the optical beam towards a sample, wherein the scanner is disposed in a rear focal plane of the first lens, and wherein the orienting the optical beam comprises varying an orientation of the scanner to telecentrically scan the sample;

splitting, by a surface of a partial reflector, the optical beam into a reference component beam and a sample component beam, wherein the reference component beam reflects off the surface of the partial reflector and the sample component beam is transmitted through the partial reflector onto a sample; and

directing, by the scanner, the reference component beam and a portion of the sample component beam reflected from the sample to a detector to generate an interference pattern.

16. The method of claim 15, further comprising collimating, by a second lens, the optical beam upon emission of the optical beam from the optical fiber prior to the directing of the optical beam by the scanner.

17. The method of claim 15, wherein the surface of the partial reflector is planar and oriented perpendicular to an optical axis of the second lens.