Electrical devices with enhanced electrochemical activity and manufacturing methods thereof
First Claim
1. An analyte sensor for detecting an analyte concentration level in a biofluid sample, comprising:
- a sensor member in the form of a fiber including a core formed of conductive material surrounded by a cladding formed of a semiconductor material including silicon carbide, the sensor member including;
a surface region of enhanced electrochemical activity on the cladding, wherein the surface region of enhanced electrochemical activity has been altered by exposure to heat to have a response to an analyte that is greater than about five times than before the exposure; and
an active region in contact with the surface region of enhanced electrochemical activity, the active region including an agent selected from among;
glucose oxidase, glucose dehydrogenase (GDH), pyrolloquinoline quinine (PQQ), and flavin adenine dinucleotide (FAD), and being adapted to be exposed to the biofluid sample.
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Accused Products
Abstract
In some aspects, a device is provided having a member with a region of enhanced electrochemical activity. In one aspect, a sensor of enhanced electrochemical activity is provided for detecting an analyte concentration level in a bio-fluid sample. The sensor may include a sensor member of a semiconductor material wherein the sensor member has a surface region of enhanced electrochemical activity. In other aspects, the member may be made of semiconducting foam having a surface region of enhanced electrochemical activity. In some embodiments, the region may be thermally-induced. Manufacturing methods and apparatus are also provided, as are numerous other aspects.
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Citations
7 Claims
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1. An analyte sensor for detecting an analyte concentration level in a biofluid sample, comprising:
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a sensor member in the form of a fiber including a core formed of conductive material surrounded by a cladding formed of a semiconductor material including silicon carbide, the sensor member including; a surface region of enhanced electrochemical activity on the cladding, wherein the surface region of enhanced electrochemical activity has been altered by exposure to heat to have a response to an analyte that is greater than about five times than before the exposure; and an active region in contact with the surface region of enhanced electrochemical activity, the active region including an agent selected from among;
glucose oxidase, glucose dehydrogenase (GDH), pyrolloquinoline quinine (PQQ), and flavin adenine dinucleotide (FAD), and being adapted to be exposed to the biofluid sample. - View Dependent Claims (2, 3, 4, 5, 6, 7)
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Specification