Method and device for improved hygienic monitoring in IVC systems
First Claim
1. A device for contamination-free removal of biological samples from a ventilated shelving storage system for laboratory animals containment cages, comprisinga support frame configured to be inserted into a filtering unit of the ventilated shelving storage system, the support frame comprising a planar plate having a seat portion and an aperture located therein adjacent the seat portion, wherein the aperture is positioned to receive a flow of air entering the filtering unit when the support frame is inserted into the filtering unit;
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a capturing scaffold having a capturing device arranged within a capturing portion of the capturing scaffold; and
a sheath associated to the capturing scaffold, wherein the capturing scaffold is inserted into the sheath and is movable in a sliding manner with respect to the sheath, when the sampling device is inserted into the support frame, to a capturing position located in the aperture of the support frame, wherein the capturing scaffold is further movable, when the sampling device is inserted into the support frame, between a closed position with the capturing portion completely inserted into the sheath and an open position with the capturing portion completely exposed to an air flow from an area of the aperture not covered by the capturing portion and a flow passage area of the ventilated shelving storage system.
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Accused Products
Abstract
The present invention concerns a device for improved hygienic monitoring of individually ventilated caging (IVC) rack systems for laboratory animals and method for contamination-free removal of biological samples from unwanted organisms from the IVC-rack system. The device allows the performance of sampling operations on a ventilated shelving system in a safe and effective manner, without interfering with the ventilation air flow. The method of the invention allows the removal and transfer of the biological sample from inside the IVC-rack in a contamination-free manner by enabling a safe transfer of the sample from inside the IVC-rack system to any further processing procedure for analysis of the biological sample outside the IVC-rack system. It is also an object of the present invention to provide a device which is adapted to be used also on existing ventilated shelving systems, allowing the refitting of existing IVC-rack systems.
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Citations
12 Claims
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1. A device for contamination-free removal of biological samples from a ventilated shelving storage system for laboratory animals containment cages, comprising
a support frame configured to be inserted into a filtering unit of the ventilated shelving storage system, the support frame comprising a planar plate having a seat portion and an aperture located therein adjacent the seat portion, wherein the aperture is positioned to receive a flow of air entering the filtering unit when the support frame is inserted into the filtering unit; - and
a sampling device configured to be removably inserted into the seat portion of the support frame, wherein the support frame is configured to receive the sampling device when the support frame is positioned in the filtering unit, the sampling device comprising; a capturing scaffold having a capturing device arranged within a capturing portion of the capturing scaffold; and a sheath associated to the capturing scaffold, wherein the capturing scaffold is inserted into the sheath and is movable in a sliding manner with respect to the sheath, when the sampling device is inserted into the support frame, to a capturing position located in the aperture of the support frame, wherein the capturing scaffold is further movable, when the sampling device is inserted into the support frame, between a closed position with the capturing portion completely inserted into the sheath and an open position with the capturing portion completely exposed to an air flow from an area of the aperture not covered by the capturing portion and a flow passage area of the ventilated shelving storage system. - View Dependent Claims (2, 3, 4, 5, 6, 12)
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7. A ventilated shelving storage system for laboratory animals containment cages comprising:
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a load-bearing structure for supporting a plurality of cages and an air guidance device comprising a filtering unit; and a biological sample removal device comprising; a support frame configured to be inserted into the filtering unit of the ventilated shelving storage system, the support frame comprising a planar plate having a seat portion and an aperture located therein adjacent the seat portion, wherein the aperture is positioned to receive a flow of air entering the filtering unit when the support frame is inserted into the filtering unit; and a sampling device configured to be removably inserted into the seat portion of the support frame, wherein the support frame is configured to receive the sampling device when the support frame is positioned in the filtering unit, the sampling device comprising; a capturing scaffold having a capturing device arranged within a capturing portion of the capturing scaffold; and a sheath associated to the capturing scaffold, wherein the capturing scaffold is inserted into the sheath and is movable in a sliding manner with respect to the sheath, when the sampling device is inserted into the support frame, to a capturing position located in the aperture of the support frame, wherein the capturing scaffold is further movable, when the sampling device is inserted into the support frame, between a closed position with the capturing portion completely inserted into the sheath and an open position with the capturing portion completely exposed to an air flow from an area of the aperture not covered by the capturing portion and a flow passage area of the ventilated shelving storage system. - View Dependent Claims (8, 9, 10)
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11. A method for contamination-free removal of biological samples from a ventilated shelving storage system for laboratory animals containment cages the method comprising:
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providing a biological sample removal device comprising; a support frame configured to be inserted into a filtering unit of the ventilated shelving storage system, the support frame comprising a planar plate having a seat portion and an aperture located therein adjacent the seat portion, wherein the aperture is positioned to receive a flow of air entering the filtering unit when the support frame is inserted into the filtering unit; and a sampling device configured to be removably inserted into the seat portion of the support frame, wherein the support frame is configured to receive the sampling device when the support frame is positioned in the filtering unit, the sampling device comprising; a capturing scaffold having a capturing device arranged within a capturing portion of the capturing scaffold; and a sheath associated to the capturing scaffold, wherein the capturing scaffold is inserted into the sheath and is movable in a sliding manner with respect to the sheath, when the sampling device is inserted into the support frame, to a capturing position located in the aperture of the support frame, wherein the capturing scaffold is further movable, when the sampling device is inserted into the support frame, between a closed position with the capturing portion completely inserted into the sheath and an open position with the capturing portion completely exposed to an air flow from an area of the aperture not covered by the capturing portion and a flow passage area of the ventilated shelving storage system; inserting the support frame into the filtering unit of the ventilated shelving storage system with the aperture positioned to receive the flow of air entering the filtering unit; positioning the capturing scaffold of the sampling device in the open position; collecting biological samples from unwanted organisms in the ventilated shelving storage system on the capturing device on the capturing scaffold of the sampling device; positioning the capturing scaffold of the sampling device of the biological sample removal device in the closed position; removing the sampling device from the support frame; transferring the sampling device to a ventilated hood; shifting the capturing scaffold, comprising the capturing device to the open position; and transferring the capturing device to a reaction vessel for analysis of the biological samples of the unwanted organisms.
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Specification