Restoring blood flow and clot removal during acute ischemic stroke

• US 10,413,310 B2
• Filed: 02/02/2015
• Issued: 09/17/2019
• Est. Priority Date: 10/17/2007
• Status: Active Grant

• Current Assignee: Covidien LP (Medtronic Plc)
• Original Assignee: Covidien LP (Medtronic Plc)
• Inventors: Ferrera, David, Cragg, Andrew, Fulkerson, John
• Primary Examiner(s): Nguyen, Tuan V
• Application Number:
  US14/611,564
• Publication Number:
  US 20150157346A1
• Time in Patent Office: 1,688 Days
• CPC Class Codes: A61B 17/221 Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions surgical snare instruments A61B17/32056
• CPC Class Codes: A61B 17/320783 through side-hole, e.g. sliding or rotating cutter inside catheter
• CPC Class Codes: A61B 2017/22039 eccentric
• CPC Class Codes: A61B 2017/22094 for crossing total occlusions, i.e. piercing
• CPC Class Codes: A61B 2017/2212 having a closed distal end, e.g. a loop
• CPC Class Codes: A61F 2/013 Distal protection devices, i.e. devices placed distally in combination with another endovascular procedure, e.g. angioplasty or stenting
• CPC Class Codes: A61F 2002/016 made from wire-like elements
• CPC Class Codes: A61F 2230/0069 cylindrical
• CPC Class Codes: A61F 2230/0076 ellipsoidal or ovoid
• CPC Class Codes: A61F 2230/0097 Harpoon-shaped
• CPC Class Codes: A61M 25/09 Guide wires
• CPC Class Codes: A61M 25/09025 with sliding mandrils

Abstract

Devices for restoring blood flow to facilitate lysis of clots and/or enable capture of clots are disclosed. The devices can be configured to be disposed within a lumen of a microcatheter that is inserted within neurovasculature above a carotid siphon to a location of a clot. The devices can include an elongate pusher member and a self-expandable capturing member coupled to a distal end of the elongate pusher member. The capturing member can comprise a generally cylindrical body having an cell structure that is configured to compress the clot against an inner wall of the neurovasculature and capture the clot at least partially on a surface of the generally cylindrical body upon deployment of the capturing member from the microcatheter, thereby restoring blood flow to the neurovasculature downstream of the clot.

Claims

1. A method for removing an embolus from a blood vessel of a subject'"'"'s neurovasculature, comprising:

delivering a capturing device to the blood vessel;

engaging the embolus with the capturing device; and

moving the embolus down the intracranial tree into the carotid siphon without moving the capturing device into a catheter.

2. The method of claim 1, further comprising moving the embolus into the cavernous carotid without moving the capturing device into a catheter.

3. The method of claim 2, further comprising moving the embolus into the common carotid without moving the capturing device into a catheter.

4. The method of claim 2, further comprising retracting the capturing device into a catheter.

5. The method of claim 1, wherein the embolus is removed from the blood vessel by withdrawing the capturing device without fragmenting the embolus.

6. A method for treating a subject having a clot in the subject'"'"'s neurovasculature, the method comprising:

capturing at least a portion of a clot in the subject'"'"'s neurovasculature with a capturing device; and

without recapturing the capturing device into a catheter, retracting the capturing device together with the captured portion of the clot into the carotid siphon.

7. The method of claim 6, further comprising retracting the capturing device together with the captured portion of the clot into the cavernous carotid without recapturing the capturing device into a catheter.

8. The method of claim 7, further comprising retracting the capturing device together with the captured portion of the clot into the common carotid without recapturing the capturing device into a catheter.

9. The method of claim 7, further comprising retracting the capturing device into a catheter.

10. The method of claim 6, wherein the captured portion of the clot is removed from the blood vessel by withdrawing the capturing device without fragmenting the embolus.