Apparatus for artificial cardiac stimulation and method of using same

• US 10,413,720 B2
• Filed: 04/10/2013
• Issued: 09/17/2019
• Est. Priority Date: 04/10/2012
• Status: Active Grant

• Current Assignee: Gloucestershire Hospitals NHS Foundation Trust (Government of United Kingdom)
• Original Assignee: Gloucestershire Hospitals NHS Foundation Trust (Government of United Kingdom)
• Inventors: Nuta, Bogdan, Lines, Ian
• Primary Examiner(s): Fairchild, Mallika D
• Application Number:
  US14/391,425
• Publication Number:
  US 20150088219A1
• Time in Patent Office: 2,351 Days
• CPC Class Codes: A61F 2/82 Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents stent-grafts for tubular structures of the body other than blood vessels A61F2/04; stent-grafts for blood vessels A61F2/07; instruments specially adapted for placement or removal of stents or stent-grafts A61F2/95; for closing wounds, or holding wounds closed A61B17/04 - A61B17/115; dilators A61M29/00
• CPC Class Codes: A61F 2250/001 for adjusting a diameter
• CPC Class Codes: A61N 1/056 Transvascular endocardial electrode systems
• CPC Class Codes: A61N 1/368 comprising more than one electrode co-operating with different heart regions A61N1/3622, A61N1/3627 take precedence
• CPC Class Codes: A61N 1/3684 for stimulating the heart at multiple sites of the ventricle or the atrium
• CPC Class Codes: A61N 1/36842 Multi-site stimulation in the same chamber
• CPC Class Codes: A61N 1/36843 Bi-ventricular stimulation
• CPC Class Codes: A61N 1/37288 Communication to several implantable medical devices within one patient
• CPC Class Codes: A61N 1/3756 Casings with electrodes thereon, e.g. leadless stimulators
• CPC Class Codes: A61N 2001/0585 Coronary sinus electrodes

Abstract

A system for artificial stimulation of the heart of a subject is provided, the system comprising a controller comprising a receiver for receiving signal data, a processor for processing received signal data, and a transmitter for transmitting signal data; a sensing stent for location in the proximal coronary sinus of the subject, the sensing stent electrode comprising a sensing electrode assembly for sensing atrial and/or ventricular signals from the heart of the subject and a transmitting assembly for transmitting signal data to the receiver of the controller; and a stimulation stent for location in a vein of the subject distal of the sensing stent, the stimulation stent comprising a receiver for receiving signal data from the transmitter of the controller and an electrode assembly for providing a stimulating electrical signal to the heart of the subject in response to the data received.

Claims

1. A method for providing stimulation to a heart of a subject, the heart comprising a coronary sinus having a proximal region with an ostium, a left atrium, a left ventricle, an oblique vein and a middle cardiac vein, the method comprising:

sensing electrical activity of the heart at the ostium of the proximal region of the coronary sinus using a single sensing stent, the single sensing stent implanted in the coronary sinus, the sensing stent operable for sensing purposes only;

transmitting first signal data from the ostium of the coronary sinus to a controller;

generating second signal data for providing electrical stimulation to target tissue of the heart in response to the signal data received from the ostium of the coronary sinus transmitting the second signal data to a stimulation stent for stimulation of the target tissue, wherein the stimulation stent is located in a vein of the heart distal of the ostium of the coronary sinus; and

providing electrical stimulation to the target tissue of the heart in response to the second signal data, wherein the electrical stimulation is provided to the tissue of the heart distal of the ostium of the coronary;

wherein signal data are transmitted from the sensing stent to the controller and from the controller to the stimulation stent remotely without using leads.

2. The method according to claim 1, wherein pacing of the heart is provided at a single site.

3. The method according to claim 1, wherein the second signal data are transmitted to a plurality of stimulation stents.

4. The method according to claim 1, wherein electrical stimulation is provided to the left atrium of the heart.

5. The method according to claim 1, wherein electrical stimulation is provided to a mid to distal location of the coronary sinus.

6. The method according to claim 1, wherein electrical stimulation is provided to the left ventricle of the heart at a plurality of sites.

7. A method for the biventricular pacing of a heart of a subject, the heart comprising a coronary sinus having a proximal region with an ostium, a left ventricle and a right ventricle, the method comprising:

sensing electrical activity of the heart at the ostium of the proximal region of the coronary sinus using a single sensing stent, the single sensing stent implanted in the coronary sinus, the sensing stent operable for sensing purposes only;

transmitting first signal data from the ostium of the coronary sinus to a controller;

generating second signal data for providing electrical stimulation to target tissue of the heart in response to the signal data received from the ostium of the coronary sinus;

transmitting the second signal data to a plurality of stimulation stents disposed in a vein of the heart distal of the ostium of the coronary sinus for multisite stimulation of the left ventricle and stimulation stent disposed in a vein of the heart distal of the ostium of the coronary sinus for stimulation of the right ventricle; and

providing electrical stimulation to both the left and right ventricles in response to the second signal data, wherein the electrical stimulation is provided to the tissue of the heart distal of the ostium of the coronary sinus;

wherein signal data are transmitted from the sensing stent to the controller and from the controller to the stimulation stems remotely without using leads.