Detection of chronotropic incompetence

• US 10,420,514 B2
• Filed: 10/18/2016
• Issued: 09/24/2019
• Est. Priority Date: 02/25/2016
• Status: Active Grant

• Current Assignee: Samsung Electronics Co. Ltd.
• Original Assignee: Samsung Electronics Co. Ltd.
• Inventors: Jain, Jawahar, Wortham, Cody, Young, James, Sadi, Sajid, Mistry, Pranav
• Primary Examiner(s): Stice, Paula J
• Application Number:
  US15/296,689
• Publication Number:
  US 20170245805A1
• Time in Patent Office: 1,071 Days
• CPC Class Codes: A61B 5/02055 Simultaneously evaluating both cardiovascular condition and temperature
• CPC Class Codes: A61B 5/024 Detecting, measuring or recording pulse rate or heart rate A61B5/0205, A61B5/021 take precedence
• CPC Class Codes: A61B 5/08 Detecting, measuring or recording devices for evaluating the respiratory organs A61B5/0205 takes precedence
• CPC Class Codes: A61B 5/1118 Determining activity level
• CPC Class Codes: A61B 5/7275 Determining trends in physiological measurement data; Predicting development of a medical condition based on physiological measurements, e.g. determining a risk factor
• CPC Class Codes: A61B 7/003 Detecting lung or respiration noise
• CPC Class Codes: G16H 50/20 for computer-aided diagnosis, e.g. based on medical expert systems
• CPC Class Codes: G16H 50/30 for calculating health indices; for individual health risk assessment

Abstract

Detecting chronotropic incompetence includes determining, using a processor, a baseline cardiac health measure for a user based upon an estimate of activity level for the user, validating, using the processor, the estimate of activity level for the user with a validation factor determined from sensor data and determining, using the processor, a cardiac health measure for the user from the sensor data. A signal indicating chronotropic incompetence for the user can be provided by the processor based upon a comparison of the cardiac health measure for the user with the baseline cardiac health measure.

Claims

1. A method of detecting chronotropic incompetence, comprising:

in response to receiving a user input specifying an estimate of activity level for the user, determining, using a processor, a baseline cardiac health measure for the user from a memory, wherein the baseline cardiac health measure includes a baseline validation factor for the user and corresponds to the estimate of activity level for the user;

determining, using the processor, a validation factor for the user from first sensor data generated by a first sensor, wherein the first sensor data corresponds to a same time period as the estimate of activity level for the user;

validating the estimate of activity level for the user with the validation factor by comparing the validation factor with the baseline validation factor;

determining a cardiac health measure for the user from second sensor data generated by a second sensor corresponding to the same time period, wherein the first and second sensors are coupled to the processor;

comparing the cardiac health measure for the user with the baseline cardiac health measure; and

providing, using the processor, a signal indicating chronotropic incompetence for the user based upon the comparing of the cardiac health measure for the user with the baseline cardiac health measure.

2. The method of claim 1, further comprising:

determining that the estimate of activity level for the user is in a defined range of activity level prior to determining the baseline cardiac health measure.

3. The method of claim 1, wherein the second sensor is a heart rate sensor and the cardiac health measure includes heart rate or a covariance calculated using heart rate.

4. The method of claim 1, wherein the estimate of activity level is a rate of perceived exertion for the user.

5. The method of claim 1, further comprising:

automatically determining a confounder from sensor data comprising at least the second sensor data; and

adjusting the comparing for the confounder.

6. The method of claim 5, wherein the confounder is sleep deprivation.

7. The method of claim 5, wherein the confounder is high stress.

8. The method of claim 1, wherein the first sensor is an accelerometer and the validation factor is expended energy of the user.

9. The method of claim 1, wherein the first sensor is a microphone and the validation factor is respiratory sound of the user.

10. An apparatus for detecting chronotropic incompetence, comprising:

a first sensor configured to generate first sensor data;

a second sensor configured to generate second sensor data;

a memory configured to store the first and second sensor data and a baseline cardiac health measure; and

a processor, coupled to the memory and the first sensor and the second sensor, wherein the processor is configured to;

in response to receiving a user input specifying an estimate of activity level for the user, determine the baseline cardiac health measure for the user from the memory, wherein the baseline cardiac health measure includes a baseline validation factor for the user and corresponds to the estimate of activity level for the user;

determine a validation factor for the user from first sensor data generated by a first sensor, wherein the first sensor data corresponds to a same time period as the estimate of activity level for the user;

validate the estimate of activity level for the user with the validation factor by comparing the validation factor with the baseline validation factor;

determine a cardiac health measure for the user from second sensor data generated by a second sensor corresponding to the same time period;

compare the cardiac health measure for the user with the baseline cardiac health measure; and

provide a signal indicating chronotropic incompetence for the user based upon the comparison of the cardiac health measure for the user with the baseline cardiac health measure.

11. The apparatus of claim 10, wherein the processor is further configured to:

determine that the estimate of activity level for the user is in a defined range of activity level prior to determining the baseline cardiac health measure.

12. The apparatus of claim 10, wherein the second sensor is a heart rate sensor and the cardiac health measure includes heart rate or a covariance calculated using heart rate.

13. The apparatus of claim 10, wherein the processor is further configured to:

automatically determine a confounder from sensor data comprising at least the second sensor data; and

adjust the comparing for the confounder.

14. The apparatus of claim 13, wherein the confounder is sleep deprivation.

15. The apparatus of claim 13, wherein the confounder is high stress.

16. The apparatus of claim 10, wherein the first sensor is an accelerometer and the validation factor is expended energy of the user.

17. The apparatus of claim 10, wherein the first sensor is a microphone and the validation factor is respiratory sound of the user.

18. A computer program product comprising a computer readable storage medium having program code stored thereon, the program code executable by a processor to perform operations for detecting chronotropic incompetence comprising:

in response to receiving a user input specifying an estimate of activity level for the user, determining a baseline cardiac health measure for the user from a memory, wherein the baseline cardiac health measure includes a baseline validation factor and corresponds to the estimate of activity level for the user;

determining a validation factor for the user from first sensor data generated by a first sensor, wherein the first sensor data corresponds to a same time period as the estimate of activity level for the user;

validating the estimate of activity level for the user with the validation factor by comparing the validation factor with the baseline validation factor;

determining a cardiac health measure for the user from second sensor data generated by a second sensor corresponding to the same time period, wherein the first and second sensors are coupled to the processor;

comparing the cardiac health measure for the user with the baseline cardiac health measure; and

providing a signal indicating chronotropic incompetence for the user based upon the comparing of the cardiac health measure for the user with the baseline cardiac health measure.

19. The computer program product of claim 18, wherein the program code is executable by the processor to perform operations further comprising:

determining that the estimate of activity level for the user is in a defined range of activity level prior to determining the baseline cardiac health measure.

20. The computer program product of claim 18, wherein the program code is executable by the processor to perform operations further comprising:

automatically determining a confounder from sensor data comprising at least the second sensor data; and

adjusting the comparing for the confounder.

21. A method of detecting chronotropic incompetence, comprising:

determining, using a processor, an estimate of activity level for a user from first sensor data generated by a first sensor;

determining, using the processor, a baseline cardiac health measure for the user from a memory, wherein the baseline cardiac health measure includes a baseline validation factor for the user and corresponds to the estimate of activity level for the user;

determining, using the processor, a validation factor for the user from second sensor data generated by a second sensor, wherein the second sensor data corresponds to a same time period as the estimate of activity level for the user and the first sensor data;

validating the estimate of activity level for the user with the validation factor by comparing the validation factor with the baseline validation factor;

determining a cardiac health measure for the user from third sensor data generated by a third sensor corresponding to the same time period, wherein the first, second, and third sensors and the memory are coupled to the processor;

comparing, using the processor, the cardiac health measure for the user with the baseline cardiac health measure; and

providing, using the processor, a signal indicating chronotropic incompetence for the user based upon the comparing of the cardiac health measure for the user with the baseline cardiac health measure.

22. The method of claim 21, further comprising:

determining that the estimate of activity level for the user is in a defined range of activity level prior to determining the baseline cardiac health measure.

23. The method of claim 21, wherein:

the first sensor is a microphone, the first sensor data is audio data specifying respiratory sound of the user, and the estimate of activity level for the user is determined from the audio data; and

the second sensor is an accelerometer and the validation factor is expended energy of the user.

24. The method of claim 21, wherein the third sensor is a heart rate sensor and the cardiac health measure includes heart rate or a covariance calculated using heart rate.

25. The method of claim 21, further comprising:

automatically determining a confounder from sensor data comprising at least the third sensor data; and

adjusting the comparing for the confounder.

26. The method of claim 21, wherein the confounder is sleep deprivation.

27. The method of claim 21, wherein the confounder is high stress.