Clot retrieval devices

• US 10,420,570 B2
• Filed: 08/02/2016
• Issued: 09/24/2019
• Est. Priority Date: 03/14/2013
• Status: Active Grant

• Current Assignee: Neuravi Limited (Johnson & Johnson)
• Original Assignee: Neuravi Limited (Johnson & Johnson)
• Inventors: Vale, David, Gilvarry, Michael, Brady, Eamon, Razavi, Mahmood
• Primary Examiner(s): Ton, Martin T
• Application Number:
  US15/226,389
• Publication Number:
  US 20170086862A1
• Time in Patent Office: 1,148 Days
• CPC Class Codes: A61B 17/221 Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions surgical snare instruments A61B17/32056
• CPC Class Codes: A61B 2017/22034 for gripping the obstruction or the tissue part from inside
• CPC Class Codes: A61B 2017/22061 for spreading elements apart
• CPC Class Codes: A61B 2017/22094 for crossing total occlusions, i.e. piercing
• CPC Class Codes: A61B 2017/2215 having an open distal end

Abstract

A self-expandable mechanical clot retrieval device is designed variously to dislodge, engage and retract blood clot from extremely small and tortuous vasculature. The retrieval device comprises an elongate member and a plurality of ring elements. The ring elements may comprise a plurality of struts and crowns interconnected by a tether formed at a distal end of the elongate member or may be a separate component attached thereto. At least one tether may connect each ring element to the elongate member to restrain the ring element in a collapsed configuration during delivery of the retrieval device through an intravascular microcatheter. The tether connecting the ring element to the elongate member disengages when the retrieval device is positioned at the occluded site and the microcatheter is retracted to allow the self-expandable ring elements to reach an expanded configuration.

Claims

1. A clot retrieval device comprising:

a shaft extending between a proximal end and a distal end;

a ball coupled to a distal portion of the shaft;

a plurality of independent clot engaging ring elements, the plurality of clot engaging ring elements comprising a proximal side, a distal side, and struts connected through one or more tethers between respective crowns of the distal and proximal sides of respective clot engaging ring elements, each clot engaging ring element being expandable between a retracted delivery configuration and an expanded deployed configuration,

wherein in the retracted delivery configuration, the plurality of independent clot engaging ring elements radially surround the distal portion of the shaft; and

wherein to move to the expanded deployed configuration from the retracted delivery configuration, the shaft and ball are axially translated proximally thereby applying a radial force that biases the plurality of independent clot engaging ring elements to expand to the deployed configuration.

2. The device of claim 1, wherein the plurality of independent clot engaging ring elements are each connected to at least one other of the plurality of independent clot engaging ring elements.

3. The device of claim 1, wherein in the expanded deployed configuration, a clot inlet opening is defined between the distal side of the independent clot engaging ring elements being spaced apart from the proximal side of an adjacent clot engaging ring element.

4. The device of claim 1, wherein adjacent struts of the plurality of struts of each of the plurality of independent clot engaging ring elements couple to one another in the retracted delivery configuration and uncouple from one another in the expanded deployed configuration.

5. The device of claim 4, wherein connectors of adjacent struts of the plurality of struts of each of the plurality of independent clot engaging ring elements include hooks.

6. The device of claim 1, wherein, in a partially deployed configuration, a distal end of at least one of the plurality of independent clot engaging ring elements tapers radially outwardly of the shaft.

7. The device of claim 6, further including a tube, wherein the shaft is axially translatable within a lumen of the tube.

8. The device of claim 7, wherein the tube includes a proximal collar.

9. A clot retrieval device comprising:

a shaft extending between a proximal end and a distal end;

a ball coupled to a distal portion of the shaft;

at least three independent, separately spaced clot engaging ring elements, the at least three independent clot engaging ring elements comprising zigzag struts connected through one or more connectors, each clot engaging ring element being expandable between a retracted delivery configuration and an expanded deployed configuration,

wherein in the retracted delivery configuration, the at least three independent clot engaging ring elements radially surround the distal portion of the shaft; and

wherein to move to the expanded deployed configuration from the retracted delivery configuration, the shaft and ball are axially translated proximally thereby applying a radial force that biases the at least three independent clot engaging ring elements to expand to the deployed configuration.

10. The device of claim 9, wherein the at least three independent clot engaging ring elements are each connected through one or more tethers between respective crowns of the distal and proximal sides of respective independent clot engaging ring elements.

11. The device of claim 9, wherein in the expanded deployed configuration, a clot inlet opening is defined between each adjacent clot engaging ring element.

12. The device of claim 9, wherein adjacent struts of the plurality of struts of each of the at least three independent clot engaging ring elements couple to one another in the retracted delivery configuration and uncouple from one another in the expanded deployed configuration.

13. The device of claim 12, wherein connectors of adjacent struts of the plurality of struts of each of the at least three independent clot engaging ring elements include hooks.

14. The device of claim 9, wherein, in a partially deployed configuration, a distal end of at least one of the at least three independent clot engaging ring elements tapers radially outwardly of the shaft.

15. The device of claim 9, further including a tube, wherein the shaft is axially translatable within a lumen of the tube.

16. A clot retrieval device comprising:

a shaft extending between a proximal end and a distal end;

a ball coupled to a distal portion of the shaft;

a tube, wherein the shaft is axially translatable within a lumen of the tube; and

a plurality of independent, separately spaced clot engaging ring elements, the independent clot engaging ring elements comprising struts connected through one or more connectors, each clot engaging ring element being expandable between a retracted delivery configuration, a partially deployed configuration, and an expanded deployed configuration,

wherein each strut comprises a hook lock with a first lock and a second lock, wherein each hook lock holds the neighboring hook lock to restrain the device in the retracted delivery configuration;

wherein in the retracted delivery configuration, the plurality of independent clot engaging ring elements radially surround the distal portion of the shaft, and

wherein in the partially deployed configuration, a distal end of at least one of the independent clot engaging ring elements tapers radially outwardly of the shaft;

wherein to move to the expanded deployed configuration from the retracted delivery configuration, the shaft and ball are axially translated proximally thereby applying a radial force that biases the plurality of independent clot engaging ring elements to expand to the deployed configuration.

17. The device of claim 16, wherein the plurality of independent clot engaging ring elements includes at least three independent clot engaging ring elements.

18. The device of claim 16, wherein in the expanded deployed configuration, a clot inlet opening for receiving a clot and is defined between distal and proximal sides each adjacent clot engaging ring element.

19. The device of claim 16, wherein adjacent struts of the plurality of struts of each of the plurality of independent clot engaging ring elements couple to one another in the retracted delivery configuration and uncouple from one another in the expanded deployed configuration.